Alcohol Use Disorder, Psychiatric Comorbidities, Marriage and Divorce in a High-risk Sample

  Previous studies demonstrate the associations between alcohol use disorders (AUD) and marital outcomes in general population samples, and the associations between AUD and marital outcomes have tangible costs, because a body of work shows links between marriage with better health and well-being. This study made use of data from the Collaborative Study on the […]

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Binge and High-Intensity Drinking – Laboratory Assessment and Underlying Risk Factors

  Some patterns of alcohol consumption are riskier than others. How rapid consumption of alcohol contributes to the increased risk of alcohol use disorder is unclear. We developed an experiment in which participants were given specific control over how quickly their breath alcohol concentration (BrAC) changes, and then tested for relationships to risky drinking patterns. […]

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The Research is In: It’s Nature AND Nurture

Science tells us that both our genes AND our environments shape the likelihood that we will develop problems with alcohol use. Because the COGA study has a wealth of data on both genetics and environments, our investigators are uniquely positioned to explore both simultaneously. See the summaries of a few recent publications to better understand […]

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The Importance of Genes When Determining Risk

  Alcohol use disorder is genetically influenced, but there’s no one gene that influences risk. We can now measure one’s genetic vulnerability to some common disorders using polygenic risk scores (PRS), which combine the effects of many genes into a single risk score. At the moment, PRS summarize only a small portion of an individual’s […]

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Early marriage may lead to unsafe drinking behavior by those with higher genetic risk of alcohol use

Two wedding cake toppers of a young white man and woman stand in front of wine and glasses

A new study led by Rebecca Smith, and Dr. Seung Bin Cho made use of a sample of 937 individuals from the Collaborative Study on the Genetics of Alcoholism (COGA). Their manuscript will be published in a forthcoming issue of Development and Psychopathology  and explores the association between marital status and heavy episodic drinking as […]

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