Since 1989, researchers from across the country have worked together to identify genes that increase or decrease the risk of alcohol use disorder (AUD), the progression of AUD, and factors related to treatment and remission/recovery. These findings inform prevention and treatment of AUD. More than 650 scientific papers have been written using the COGA data!
How COGA works:
Families were recruited through individuals in AUD treatment facilities (along with a general population comparison group).
Participants provided blood samples (for DNA) and completed interviews, questionnaires, and brain electrophysiology tasks. Subjects are followed over time.
Ongoing data analysis identifies new genes and pathways of risk or resilience.
History & Mission
COGA consists of three inter-related scientific projects, supported by three cores, that work together to achieve the overarching goal of understanding the role of genes, functional networks, neurobiological, and environmental factors on risk and resilience.
Meet the Research Team