About COGA

Since 1989, researchers from across the country have worked together to identify genes that increase or decrease the risk of alcohol use disorder (AUD), the progression of AUD, and factors related to treatment and remission/recovery. These findings inform prevention and treatment of AUD. More than 725 scientific papers have been written using the COGA data!

How COGA works:

Icon of multiple people.

1. Recruitment

Families were recruited through individuals in AUD treatment facilities (along with a general population comparison group).

Flask with data in it.

2. Data Collection

Participants provided blood samples (for DNA) and completed interviews, questionnaires, and brain electrophysiology tasks. Subjects are followed over time.

Microscope with a DNA lightbulb.

3. Analysis

Ongoing data analysis identifies new genes and pathways of risk or resilience.

History & Mission

COGA consists of three inter-related scientific projects, supported by three cores, that work together to achieve the overarching goal of understanding the role of genes, functional networks, neurobiological, and environmental factors on risk and resilience.

Meet the Research Team

Click here for information on our researchers!
COGA researchers group photo.


COGA research has a long history with publications going back to the early 1990s. Investigators have written more than 725 scientific papers from the COGA data. You can find them here!