COGA Publications

List of Articles Published by the Collaborative Study on the Genetics of Alcoholism (COGA) Investigators

 


For additional publications, check out our list of Articles Published by Other Research Teams Using the Data Shared by the Collaborative Study on the Genetics of Alcoholism (COGA)


 

Total number of published articles: 599

(Articles marked with 3 asterisks *** have been published in collaboration with other team of researchers)


 

2023 [4 Articles]

  1. Colbert S, Mullins N, Chan G, Meyers JL, Schulman J, Kuperman S, Lai D, Nurnberger J, Plawecki MH, Kamarajan C, Anokhin AP, Bucholz KK, Hesselbrock V, Edenberg HJ, Kramer J, Dick DM, Porjesz B, Agrawal A, Johnson EC (2023) Polygenic contributions to suicidal thoughts and behaviors in a sample ascertained for alcohol use disorders. Complex Psychiatry. DOI: 10.1159/000529164.

  2. Pandey G, Kuo SIC, Horne‐Osipenko KA, Pandey AK, Kamarajan C, de Viteri SS, Kinreich S, Chorlian DB, Kuang W, Stephenson M, Kramer J, Anokhin A, Zang Y, Kuperman S, Hesselbrock V, Schuckit M, Dick D, Chan G, McCutcheon VV, Edenberg H, Bucholz KK, Meyers JL, Porjesz B (2023) Associations of parent–adolescent closeness with P3 amplitude, frontal theta, and binge drinking among offspring with high risk for alcohol use disorder. Alcohol: Clinical and Experimental Research, 00, 1-13. PMID: 36680783; DOI: 10.1111/acer.14973.

  3. Kamarajan C, Pandey AK, Chorlian DB, Meyers JL, Kinreich S, Pandey G, Subbie Saenz de Viteri S, Zhang J, Kuang W, Barr PB, Aliev F, Anokhin AP, Plawecki MH, Kuperman S, Almasy L, Merikangas A, Brislin SJ, Bauer L, Hesselbrock V, Chan G, Kramer J, Lai D, Hartz S, Bierut LJ, McCutcheon VV, Bucholz KK, Dick DM, Schuckit MA, Edenberg HJ, Porjesz B (2023) Predicting alcohol-related memory problems in older adults: A machine learning study with multi-domain features. bioRxiv, 2022.2012.2030.522330. DOI: 10.1101/2022.12.30.522330.

  4. Thomas NS, Salvatore JE, Kuo SI, Aliev F, McCutcheon VV, Meyers JM, Bucholz KK, Brislin SJ, Chan G, Edenberg HJ, Kamarajan C, Kramer JR, Kuperman S, Pandey G, Plawecki MH, Schuckit MA, Dick DM, COGA Collaborators (2023) Genetic nurture effects for alcohol use disorder. Molecular Psychiatry, 28, 759-766. PMID: 36253439; DOI: 10.1038/s41380-022-01816-z.


2022 [29 Articles]

  1. Barr PB, Driver MN, Kuo SI, Stephenson M, Aliev F, Linner RK, Marks J, Anokhin AP, Bucholz K, Chan G, Edenberg HJ, Edwards AC, Francis MW, Hancock DB, Harden KP, Kamarajan C, Kaprio J, Kinreich S, Kramer JR, Kuperman S, Latvala A, Meyers JL, Palmer AA, Plawecki MH, Porjesz B, Rose RJ, Schuckit MA, Salvatore JE, Dick DM (2022) Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts. Molecular Psychiatry, 27(11), 4633-4641. PMID: 36195638; DOI: 10.1038/s41380-022-01801-6.

  2. Barr PB, Driver MN, Kuo SIC, Stephenson M, Aliev F, Linner RK, Anokhin AP, Bucholz K, Chan G, Edenberg HJ, Edwards AC, Francis MW, Harden KP, Kamarajan C, Kaprio J, Kinreich S, Kramer J, Kuperman S, Latvala A, Meyers JL, Palmer AA, Plawecki MH, Porjesz B, Rose RJ, Schuckit MA, Salvatore JE, Dick DM (2022) Predicting Substance Use Disorders: A Multifactorial Risk Index Combining Clinical, Environmental, and Genetic Risk Factors. medRxiv, 2022.2001.2027.22269750. DOI: 10.1101/2022.01.27.22269750.

  3. Barr PB, Mallard TT, Sanchez-Roige S, Poore HE, Linner RK, COGA Collaborators, Waldman ID, Palmer AA, Harden KP, Dick DM (2022) Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk. Translational Psychiatry, 12(1), 420. PMID: 36180423; PMCID: PMC9525649; DOI: 10.1038/s41398-022-02171-x.

  4. Cao Z, Cupertino RB, Ottino-Gonzalez J, Murphy A, Pancholi D, Juliano A, Chaarani B, Albaugh M, Yuan D, Schwab N, Stafford J, Goudriaan AE, Hutchison K, Li CR, Luijten M, Groefsema M, Momenan R, Schmaal L, Sinha R, van Holst RJ, Veltman DJ, Wiers RW, Porjesz B, Lett T, Banaschewski T, Bokde ALW, Desrivieres S, Flor H, Grigis A, Gowland P, Heinz A, Bruhl R, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Paus T, Poustka L, Hohmann S, Millenet S, Frohner JH, Robinson L, Smolka MN, Walter H, Winterer J, Schumann G, Whelan R, Bhatt RR, Zhu A, Conrod P, Jahanshad N, Thompson PM, Mackey S, Garavan H, IMAGEN Consortium, ENIGMA Addiction Working Group (2022) Cortical profiles of numerous psychiatric disorders and normal development share a common pattern. Molecular Psychiatry. PMID: 36380235. DOI: 10.1038/s41380-022-01855-6.

  5. Colbert SMC, Mullins N, Chan G, Meyers JL, Schulman J, Kuperman S, Lai D, Nurnberger J, Plawecki MH, Kamarajan C, Anokhin AP, Bucholz KK, Hesselbrock V, Edenberg HJ, Kramer J, Dick DM, Porjesz B, Agrawal A, Johnson EC (2022) Polygenic contributions to suicidal thoughts and behaviors in a sample ascertained for alcohol use disorders. medRxiv, 2022.2008.2018.22278943. DOI: 10.1101/2022.08.18.22278943.

  6. Dick DM (2022) The Promise and Peril of Genetics. Current Directions in Psychological Science, 31(6), 480-485. PMID: 36591341; PMCID: PMC9802013; DOI: 10.1177/09637214221112041.

  7. ***Ehlers CL, Schuckit MA, Hesselbrock V, Gilder DA, Wills D, Bucholz K (2022) The clinical course of antisocial behaviors in men and women of three racial groups. Journal of Psychiatric Research, 151, 319-327. PMID: 35533515; DOI: 10.1016/j.jpsychires.2022.04.038.

  8. Francis MW, Bourdon JL, Chan G, Dick DM, Edenberg HJ, Kamarajan C, Kinreich S, Kramer J, S ICK, Pandey AK, Pandey G, Smith RL, Bucholz KK, McCutcheon VV (2022) Deriving a Measure of Social Recovery Capital From the Important People and Activities Instrument: Construction and Psychometric Properties. Alcohol and Alcoholism, 57(3), 322-329. PMID: 35356964; PMCID: PMC9086804; DOI: 10.1093/alcalc/agac014.

  9. ***Gaddis N, Mathur R, Marks J, Zhou L, Quach B, Waldrop A, Levran O, Agrawal A, Randesi M, Adelson M, Jeffries PW, Martin NG, Degenhardt L, Montgomery GW, Wetherill L, Lai D, Bucholz K, Foroud T, Porjesz B, Runarsdottir V, Tyrfingsson T, Einarsson G, Gudbjartsson DF, Webb BT, Crist RC, Kranzler HR, Sherva R, Zhou H, Hulse G, Wildenauer D, Kelty E, Attia J, Holliday EG, McEvoy M, Scott RJ, Schwab SG, Maher BS, Gruza R, Kreek MJ, Nelson EC, Thorgeirsson T, Stefansson K, Berrettini WH, Gelernter J, Edenberg HJ, Bierut L, Hancock DB, Johnson EO (2022) Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. Scientific Reports, 12(1), 16873. PMID: 36207451; PMCID: PMC9546890; DOI: 10.1038/s41598-022-21003-y.

  10. Johnson EC, Colbert SMC, Jeffries PW, Tillman R, Bigdeli TB, Karcher NR, Chan G, Kuperman S, Meyers JL, Nurnberger JI, Plawecki MH, Degenhardt L, Martin NG, Kamarajan C, Schuckit MA, Murray RM, Dick DM, Edenberg HJ, D’Souza DC, Di Forti M, Porjesz B, Nelson EC, Agrawal A (2022) Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users. Schizophrenia Bulletin, PMID: 36545904; DOI: 10.1093/schbul/sbac196.

  11. Kinreich S (2022) Insights on rehabilitation programs, women, families, and COVID19. Translational Psychiatry, 12(1), 242. DOI: 10.1038/s41398-022-02008-7.

  12. Kuo SI, Poore HE, Barr PB, Chirico IS, Aliev F, Bucholz KK, Chan G, Kamarajan C, Kramer JR, McCutcheon VV, Plawecki MH, Dick DM (2022) The role of parental genotype in the intergenerational transmission of externalizing behavior: Evidence for genetic nurturance. Development and Psychopathology, 1-11. PMID: 36200344; DOI: 10.1017/S0954579422000700.

  13. Lai D, Johnson EC, Colbert S, Pandey G, Chan G, Bauer L, Francis MW, Hesselbrock V, Kamarajan C, Kramer J, Kuang W, Kuo S, Kuperman S, Liu Y, McCutcheon V, Pang Z, Plawecki MH, Schuckit M, Tischfield J, Wetherill L, Zang Y, Edenberg HJ, Porjesz B, Agrawal A, Foroud T (2022) Evaluating risk for alcohol use disorder: Polygenic risk scores and family history. Alcoholism: Clinical and Experimental Research, 46(3), 374-383. PMID: 35267208; PMCID: PMC8928056; DOI: 10.1111/acer.14772.

  14. Lai D, Schwantes-An T-HL, Abreu M, Chan G, Hesselbrock V, Kamarajan C, Liu Y, Meyers JL, Nurnberger JI, Plawecki MH, Wetherill L, Schuckit M, Zhang P, Edenberg HJ, Porjesz B, Agrawal A, Foroud T (2022) Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. medRxiv, 2022.2001.2019.22269532. DOI: 10.1101/2022.01.19.22269532.

  15. Lai D, Schwantes-An TH, Abreu M, Chan G, Hesselbrock V, Kamarajan C, Liu Y, Meyers JL, Nurnberger JI, Jr., Plawecki MH, Wetherill L, Schuckit M, Zhang P, Edenberg HJ, Porjesz B, Agrawal A, Foroud T (2022) Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. Translational Psychiatry, 12(1), 266. PMID: 35790736; DOI: 10.1038/s41398-022-02029-2.

  16. Mallard TT, Savage JE, Johnson EC, Huang Y, Edwards AC, Hottenga JJ, Grotzinger AD, Gustavson DE, Jennings MV, Anokhin A, Dick DM, Edenberg HJ, Kramer JR, Lai D, Meyers JL, Pandey AK, Harden KP, Nivard MG, de Geus EJC, Boomsma DI, Agrawal A, Davis LK, Clarke TK, Palmer AA, Sanchez-Roige S (2022) Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. American Journal of Psychiatry, 179(1), 58-70. PMID: 33985350; DOI: 10.1176/appi.ajp.2020.20091390.

  17. ***Mathur R, Fang F, Gaddis N, Hancock DB, Cho MH, Hokanson JE, Bierut LJ, Lutz SM, Young K, Smith AV, NHLBI Trans-Omics for Precision Medicine Consortium, Silverman EK, Page GP, Johnson EO (2022) GAWMerge expands GWAS sample size and diversity by combining array-based genotyping and whole-genome sequencing. Communications Biology, 5(1), 806. PMID: 35953715; PMCID: PMC9372058; DOI: 10.1038/s42003-022-03738-6.

  18. Merikangas AK, Kember RL, Plawecki MH, Kamarajan C, Chan G, Bauer L, Meyers JL, Nurnberger JI, Kramer J, Porjesz B, Edenberg HJ, Almasy L (2022) Is anxiety a pathway to Alcohol Use Disorders? A phenome-wide association study of the GABRA2 coding variant rs279858. medRxiv, 2022.2011.2021.22282301. DOI: 10.1101/2022.11.21.22282301.

  19. Nurnberger JI, Jr., Wang Y, Zang Y, Lai D, Wetherill L, Edenberg HJ, Aliev F, Plawecki MH, Chorlian D, Chan G, Bucholz K, Bauer L, Kamarajan C, Salvatore JE, Kapoor M, Hesselbrock V, Dick D, Bierut L, McCutcheon V, Meyers JL, Porjesz B, Kramer J, Kuperman S, Kinreich S, Anokhin AP, Collaborative Study on the Genetics of A (2022) High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk. Biological Psychiatry: Global Open Science, 2(4), 379-388. PMID: 36324664; PMCID: PMC9616304; DOI: 10.1016/j.bpsgos.2021.10.007.

  20. Plawecki MH, Boes J, Wetherill L, Kosobud AEK, Stangl BL, Ramchandani VA, Zimmermann US, Nurnberger JI, Schuckit M, Edenberg HJ, Pandey G, Kamarajan C, Porjesz B, Foroud T, O’Connor S (2022) Binge and high-intensity drinking-Associations with intravenous alcohol self-administration and underlying risk factors. Addiction Biology, 27(6), e13228. PMID: 36301209; PMCID: PMC9786574; DOI: 10.1111/adb.13228.

  21. Popova D, Gameiro-Ros I, Youssef MM, Zalamea P, Morris AD, Prytkova I, Jadali A, Kwan KY, Kamarajan C, Salvatore JE, Xuei X, Chorlian DB, Porjesz B, Kuperman S, Dick DM, Goate A, Edenberg HJ, Tischfield JA, Pang ZP, Slesinger PA, Hart RP (2022) Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. bioRxiv, 2022.2005.2024.493086. DOI: 10.1101/2022.05.24.493086.

  22. Popova D, Gameiro-Ros I, Youssef MM, Zalamea P, Morris AD, Prytkova I, Jadali A, Kwan KY, Kamarajan C, Salvatore JE, Xuei X, Chorlian DB, Porjesz B, Kuperman S, Dick DM, Goate A, Edenberg HJ, Tischfield JA, Pang ZP, Slesinger PA, Hart RP (2022) Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. Molecular Psychiatry, 1-13. PMID: 36207584; PMCID: PMC9542475; DOI: 10.1038/s41380-022-01818-x.

  23. Schuckit MA (2022) AUD Risk, Diagnoses, and Course in a Prospective Study Across Two Generations: Implications for Prevention. Alcohol Research: Current Reviews, 42(1), 01. PMID: 35036241; PMCID: PMC8747891; DOI: 10.35946/arcr.v42.1.01.

  24. Song X, Gao HY, Herrup K, Hart RP (2022) Optimized splitting of mixed-species RNA sequencing data. Journal of Bioinformatics and Computational Biology, 2250001. PMID: 34991436; DOI: 10.1142/S0219720022500019.

  25. Stephenson M, Aliev F, Kuo SIC, Edwards AC, Pandey G, Su J, Kamarajan C, Dick D, Salvatore JE (2022) The role of adolescent social relationships in promoting alcohol resistance: Interrupting the intergenerational transmission of alcohol misuse. Development and Psychopathology, 1-15. DOI: 10.1017/S0954579422000785.

  26. Su J, Kuo SI, Trevino A, Barr PB, Aliev F, Bucholz K, Chan G, Edenberg HJ, Kuperman S, Lai D, Meyers JL, Pandey G, Porjesz B, Dick DM (2022) Examining social genetic effects on educational attainment via parental educational attainment, income, and parenting. Journal of Family Psychology, 36(8), 1340-1350. PMID: 35666911; PMCID: PMC9733825; DOI: 10.1037/fam0001003.

  27. Thomas NS, Barr P, Aliev F, Stephenson M, Kuo SI, Chan G, Dick DM, Edenberg HJ, Hesselbrock V, Kamarajan C, Kuperman S, Salvatore JE (2022) Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation. Behavior Genetics, 52(4-5), 268-280. PMID: 35674916; DOI: 10.1007/s10519-022-10104-z.

  28. Thomas NS, Kuo SI, Aliev F, McCutcheon VV, Meyers JM, Chan G, Hesselbrock V, Kamarajan C, Kinreich S, Kramer JR, Kuperman S, Lai D, Plawecki MH, Porjesz B, Schuckit MA, Dick DM, Bucholz KK, Salvatore JE (2022) Alcohol use disorder, psychiatric comorbidities, marriage and divorce in a high-risk sample. Psychology of Addictive Behaviors, 36(4), 364-374. PMID: 35617219; PMCID: PMC9247836; DOI: 10.1037/adb0000840.

  29. Tielbeek JJ, Uffelmann E, Williams BS, Colodro-Conde L, Gagnon E, Mallard TT, Levitt BE, Jansen PR, Johansson A, Sallis HM, Pistis G, Saunders GRB, Allegrini AG, Rimfeld K, Konte B, Klein M, Hartmann AM, Salvatore JE, Nolte IM, Demontis D, Malmberg ALK, Burt SA, Savage JE, Sugden K, Poulton R, Harris KM, Vrieze S, McGue M, Iacono WG, Mota NR, Mill J, Viana JF, Mitchell BL, Morosoli JJ, Andlauer TFM, Ouellet-Morin I, Tremblay RE, Cote SM, Gouin JP, Brendgen MR, Dionne G, Vitaro F, Lupton MK, Martin NG, COGA Consortium, Spit for Science Working Group, Castelao E, Raikkonen K, Eriksson JG, Lahti J, Hartman CA, Oldehinkel AJ, Snieder H, Liu H, Preisig M, Whipp A, Vuoksimaa E, Lu Y, Jern P, Rujescu D, Giegling I, Palviainen T, Kaprio J, Harden KP, Munafo MR, Morneau-Vaillancourt G, Plomin R, Viding E, Boutwell BB, Aliev F, Dick DM, Popma A, Faraone SV, Borglum AD, Medland SE, Franke B, Boivin M, Pingault JB, Glennon JC, Barnes JC, Fisher SE, Moffitt TE, Caspi A, Polderman TJC, Posthuma D (2022) Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis. Molecular Psychiatry, 27(11), 4453-4463. PMID: 36284158; DOI: 10.1038/s41380-022-01793-3.


2021 [18 Articles]

  1. Bender AK, Meyers JL, di Viteri SS, Schuckit M, Chan G, Acion L, Kamarajan C, Kramer J, Anohkin A, Kinreich S, Pandey A, Hesselbrock V, Hesselbrock M, Bucholz KK, McCutcheon VV (2021) A latent class analysis of alcohol and posttraumatic stress symptoms among offspring of parents with and without alcohol use disorder. Addictive Behaviors, 112, 106640. PMID: 32957005; DOI: 10.1016/j.addbeh.2020.106640.

  2. Cox J, Sherva R, Wetherill L, Foroud T, Edenberg HJ, Kranzler HR, Gelernter J, Farrer LA (2021) Genome-wide association study of stimulant dependence. Translational Psychiatry, 11(1), 363. PMID: 34226506; PMCID: PMC8257618; DOI: 10.1038/s41398-021-01440-5.

  3. Johnson EC, Aliev F, Meyers JL, Salvatore JE, Tillman R, Chang Y, Docherty AR, Bogdan R, Acion L, Chan G, Chorlian DB, Kamarajan C, Kuperman S, Pandey A, Plawecki MH, Schuckit M, Tischfield J, Edenberg HJ, Bucholz KK, Nurnberger JI, Porjesz B, Hesselbrock V, Dick DM, Kramer JR, Agrawal A (2021) Associations between Suicidal Thoughts and Behaviors and Genetic Liability for Cognitive Performance, Depression, and Risk-Taking in a High-Risk Sample. Complex Psychiatry, 7(1-2), 34-44. PMID: 35592092; PMCID: PMC8443930; DOI: 10.1159/000517169.

  4. Johnson EC, Sanchez-Roige S, Acion L, Adams MJ, Bucholz KK, Chan G, Chao MJ, Chorlian DB, Dick DM, Edenberg HJ, Foroud T, Hayward C, Heron J, Hesselbrock V, Hickman M, Kendler KS, Kinreich S, Kramer J, Kuo SI, Kuperman S, Lai D, McIntosh AM, Meyers JL, Plawecki MH, Porjesz B, Porteous D, Schuckit MA, Su J, Zang Y, Palmer AA, Agrawal A, Clarke TK, Edwards AC (2021) Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples. Psychological Medicine, 51(7), 1147-1156. PMID: 31955720; PMCID: PMC7405725; DOI: 10.1017/S0033291719004045.

  5. Kapoor M, Chao MJ, Johnson EC, Novikova G, Lai D, Meyers JL, Schulman J, Nurnberger JI, Jr., Porjesz B, Liu Y, Collaborative Study on the Genetics of A, Foroud T, Edenberg HJ, Marcora E, Agrawal A, Goate A (2021) Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases. Nature Communications, 12(1), 5071. PMID: 34417470; PMCID: PMC8379159; DOI: 10.1038/s41467-021-25392-y.

  6. Karlsson Linner R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S, COGA Collaborators, Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM (2021) Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Nature Neuroscience, 24(10), 1367-1376. PMID: 34446935; PMCID: PMC8484054; DOI: 10.1038/s41593-021-00908-3.

  7. Kinreich S, McCutcheon VV, Aliev F, Meyers JL, Kamarajan C, Pandey AK, Chorlian DB, Zhang J, Kuang W, Pandey G, Viteri SS, Francis MW, Chan G, Bourdon JL, Dick DM, Anokhin AP, Bauer L, Hesselbrock V, Schuckit MA, Nurnberger JI, Jr., Foroud TM, Salvatore JE, Bucholz KK, Porjesz B (2021) Predicting alcohol use disorder remission: a longitudinal multimodal multi-featured machine learning approach. Translational Psychiatry, 11(1), 166. PMID: 33723218; PMCID: PMC7960734; DOI: 10.1038/s41398-021-01281-2.

  8. Kinreich S, Meyers JL, Maron-Katz A, Kamarajan C, Pandey AK, Chorlian DB, Zhang J, Pandey G, Subbie-Saenz de Viteri S, Pitti D, Anokhin AP, Bauer L, Hesselbrock V, Schuckit MA, Edenberg HJ, Porjesz B (2019) Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study. Molecular Psychiatry, 26(4), 1133-1141. PMID: 31595034; PMCID: PMC7138692; DOI: 10.1038/s41380-019-0534-x.

  9. Kuo SI, Salvatore JE, Barr PB, Aliev F, Anokhin A, Bucholz KK, Chan G, Edenberg HJ, Hesselbrock V, Kamarajan C, Kramer JR, Lai D, Mallard TT, Nurnberger JI, Jr., Pandey G, Plawecki MH, Sanchez-Roige S, Waldman I, Palmer AA, Externalizing Consortium, Dick DM (2021) Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance Use. Behavior Genetics, 51(5), 543-558. PMID: 34117972; PMCID: PMC8403154; DOI: 10.1007/s10519-021-10067-7.

  10. Lai D, Kapoor M, Wetherill L, Schwandt M, Ramchandani VA, Goldman D, Chao M, Almasy L, Bucholz K, Hart RP, Kamarajan C, Meyers JL, Nurnberger JI, Tischfield J, Edenberg HJ, Schuckit M, Goate A, Scott DM, Porjesz B, Agrawal A, Foroud T (2021) Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 186(3), 151-161. PMID: 32652861; PMCID: PMC9376735; DOI: 10.1002/ajmg.b.32805.

  11. Meyers JL, Chorlian DB, Bigdeli TB, Johnson EC, Aliev F, Agrawal A, Almasy L, Anokhin A, Edenberg HJ, Foroud T, Goate A, Kamarajan C, Kinreich S, Nurnberger J, Pandey AK, Pandey G, Plawecki MH, Salvatore JE, Zhang J, Fanous A, Porjesz B (2021) The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences. Translational Psychiatry, 11(1), 54. PMID: 33446638; PMCID: PMC7809462; DOI: 10.1038/s41398-020-01185-7.

  12. Meyers JL, Zhang J, Chorlian DB, Pandey AK, Kamarajan C, Wang JC, Wetherill L, Lai D, Chao M, Chan G, Kinreich S, Kapoor M, Bertelsen S, McClintick J, Bauer L, Hesselbrock V, Kuperman S, Kramer J, Salvatore JE, Dick DM, Agrawal A, Foroud T, Edenberg HJ, Goate A, Porjesz B (2021) A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior. Molecular Psychiatry, 26(9), 5040-5052. PMID: 32433515; PMCID: PMC8503860; DOI: 10.1038/s41380-020-0777-6.

  13. Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hubel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppa VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodriguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boehm I, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramis G, Esko T, Estivill X, Farmer A, Favaro A, Fernandez-Aranda F, Fichter MM, Fischer K, Focker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jimenez-Murcia S, Julia A, Kalsi G, Kaminska D, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O’Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op’t Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Birgegard A, Lichtenstein P, Norring C, Landen M, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Gaebel W, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Mannisto S, Muller-Myhsok B, Murray AD, Nurnberger JI, Preuss U, Raikkonen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Nothen MM, Palmer AA, Penninx B, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, Heath AC, Montgomery GW, Martin NG, Sullivan PF, Kaprio J, Breen G, Gelernter J, Edenberg HJ, Bulik CM, Agrawal A (2021) Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology, 26(1), e12880. PMID: 32064741; PMCID: PMC7429266; DOI: 10.1111/adb.12880.

  14. Rao X, Thapa KS, Chen AB, Lin H, Gao H, Reiter JL, Hargreaves KA, Ipe J, Lai D, Xuei X, Wang Y, Gu H, Kapoor M, Farris SP, Tischfield J, Foroud T, Goate AM, Skaar TC, Mayfield RD, Edenberg HJ, Liu Y (2021) Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders. Molecular Psychiatry, 26(4), 1142-1151. PMID: 31477794; PMCID: PMC7050407; DOI: 10.1038/s41380-019-0508-z.

  15. Smit DJA, Andreassen OA, Boomsma DI, Burwell SJ, Chorlian DB, de Geus EJC, Elvsashagen T, Gordon RL, Harper J, Hegerl U, Hensch T, Iacono WG, Jawinski P, Jonsson EG, Luykx JJ, Magne CL, Malone SM, Medland SE, Meyers JL, Moberget T, Porjesz B, Sander C, Sisodiya SM, Thompson PM, van Beijsterveldt CEM, van Dellen E, Via M, Wright MJ (2021) Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity. Brain and Behavior, 11(8), e02188. PMID: 34291596; PMCID: PMC8413828; DOI: 10.1002/brb3.2188.

  16. Su J, Kuo SI, Aliev F, Chan G, Edenberg HJ, Kamarajan C, McCutcheon VV, Meyers JL, Schuckit M, Tischfield J, Dick DM (2021) The associations between polygenic risk, sensation seeking, social support, and alcohol use in adulthood. Journal of Abnormal Psychology, 130(5), 525-536. PMID: 34472888; DOI: 10.1037/abn0000568.

  17. Tong TT, Vaidya JG, Kramer JR, Kuperman S, Langbehn DR, O’Leary DS (2021) Impact of binge drinking during college on resting state functional connectivity. Drug and Alcohol Dependence, 227, 108935. PMID: 34388578; PMCID: PMC8464531; DOI: 10.1016/j.drugalcdep.2021.108935.

  18. Xu KY, Presnall N, Mintz CM, Borodovsky JT, Bhat NR, Bierut LJ, Grucza RA (2021) Association of Opioid Use Disorder Treatment With Alcohol-Related Acute Events. JAMA Network Open, 4(2), e210061. PMID: 33625511; PMCID: PMC7905500; DOI: 10.1001/jamanetworkopen.2021.0061.


2020 [18 Articles]

  1. Barr PB, Ksinan A, Su J, Johnson EC, Meyers JL, Wetherill L, Latvala A, Aliev F, Chan G, Kuperman S, Nurnberger J, Kamarajan C, Anokhin A, Agrawal A, Rose RJ, Edenberg HJ, Schuckit M, Kaprio J, Dick DM (2020) Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples. Translational Psychiatry, 10(1), 196. PMID: 32555147; PMCID: PMC7303212; DOI: 10.1038/s41398-020-00865-8.

  2. Barr PB, Salvatore JE, Wetherill L, Anokhin A, Chan G, Edenberg HJ, Kuperman S, Meyers J, Nurnberger J, Porjesz B, Schuckit M, Dick DM (2020) A Family-Based Genome Wide Association Study of Externalizing Behaviors. Behavior Genetics, 50(3), 175-183. PMID: 32239439; PMCID: PMC7243710; DOI: 10.1007/s10519-020-09999-3.

  3. Bourdon JL, Tillman R, Francis MW, Dick DM, Stephenson M, Kamarajan C, Edenberg HJ, Kramer J, Kuperman S, Bucholz KK, McCutcheon VV (2020) Characterization of Service Use for Alcohol Problems Across Generations and Sex in Adults With Alcohol Use Disorder. Alcoholism: Clinical and Experimental Research, 44(3), 746-757. PMID: 31984526; PMCID: PMC7069784; DOI: 10.1111/acer.14290.

  4. Chester DS, Bucholz KK, Chan G, Kamarajan C, Pandey AK, Wetherill L, Kramer JR, Nurnberger JI, Jr., Salvatore JE, Dick DM (2020) Alcohol-Related, Drug-Related, and Non-Substance-Related Aggression: 3 Facets of a Single Construct or 3 Distinct Constructs? Alcoholism: Clinical and Experimental Research, 44(9), 1852-1861. PMID: 32761940; PMCID: PMC7722121; DOI: 10.1111/acer.14412.

  5. Cho SB, Smith RL, Bucholz K, Chan G, Edenberg HJ, Hesselbrock V, Kramer J, McCutcheon VV, Nurnberger J, Schuckit M, Zang Y, Dick DM, Salvatore JE (2020) Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk. Development and Psychopathology, 1-10. PMID: 32611468; DOI: 10.1017/S0954579420000371.

  6. Halikere A, Popova D, Scarnati MS, Hamod A, Swerdel MR, Moore JC, Tischfield JA, Hart RP, Pang ZP (2020) Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons. Molecular Psychiatry, 25(7), 1406-1419. PMID: 31481756; PMCID: PMC7051890; DOI: 10.1038/s41380-019-0507-0.

  7. Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PAF, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S, Psychiatric Genomics Consortium Substance Use Disorders W, Davis LK, Bogdan R, Gelernter J, Edenberg HJ, Stefansson K, Borglum AD, Agrawal A (2020) A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry, 7(12), 1032-1045. PMID: 33096046; PMCID: PMC7674631; DOI: 10.1016/S2215-0366(20)30339-4.

  8. Kramer J, Dick DM, King A, Ray LA, Sher KJ, Vena A, Vendruscolo LF, Acion L (2020) Mechanisms of Alcohol Addiction: Bridging Human and Animal Studies. Alcohol and Alcoholism, 55(6), 603-607. PMID: 32781467; PMCID: PMC7576503; DOI: 10.1093/alcalc/agaa068.

  9. Lai D, Wetherill L, Kapoor M, Johnson EC, Schwandt M, Ramchandani VA, Goldman D, Joslyn G, Rao X, Liu Y, Farris S, Mayfield RD, Dick D, Hesselbrock V, Kramer J, McCutcheon VV, Nurnberger J, Tischfield J, Goate A, Edenberg HJ, Porjesz B, Agrawal A, Foroud T, Schuckit M (2020) Genome-wide association studies of the self-rating of effects of ethanol (SRE). Addiction Biology, 25(2), e12800. PMID: 31270906; PMCID: PMC6940552; DOI: 10.1111/adb.12800.

  10. McClintick JN, Thapa K, Liu Y, Xuei X, Edenberg HJ (2020) Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. Alcohol, 85, 119-126. PMID: 31923563; PMCID: PMC7237278; DOI: 10.1016/j.alcohol.2019.12.004.

  11. Pandey G, Seay MJ, Meyers JL, Chorlian DB, Pandey AK, Kamarajan C, Ehrenberg M, Pitti D, Kinreich S, Subbie-Saenz de Viteri S, Acion L, Anokhin A, Bauer L, Chan G, Edenberg H, Hesselbrock V, Kuperman S, McCutcheon VV, Bucholz KK, Schuckit M, Porjesz B (2020) Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity. Alcoholism: Clinical and Experimental Research, 44(3), 697-710. PMID: 31957047; PMCID: PMC8357185; DOI: 10.1111/acer.14280.

  12. Polimanti R, Walters RK, Johnson EC, McClintick JN, Adkins AE, Adkins DE, Bacanu SA, Bierut LJ, Bigdeli TB, Brown S, Bucholz KK, Copeland WE, Costello EJ, Degenhardt L, Farrer LA, Foroud TM, Fox L, Goate AM, Grucza R, Hack LM, Hancock DB, Hartz SM, Heath AC, Hewitt JK, Hopfer CJ, Johnson EO, Kendler KS, Kranzler HR, Krauter K, Lai D, Madden PAF, Martin NG, Maes HH, Nelson EC, Peterson RE, Porjesz B, Riley BP, Saccone N, Stallings M, Wall TL, Webb BT, Wetherill L, Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Edenberg HJ, Agrawal A, Gelernter J (2020) Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. Molecular Psychiatry, 25(8), 1673-1687. PMID: 32099098; PMCID: PMC7392789; DOI: 10.1038/s41380-020-0677-9.

  13. Salvatore JE, Barr PB, Stephenson M, Aliev F, Kuo SI, Su J, Agrawal A, Almasy L, Bierut L, Bucholz K, Chan G, Edenberg HJ, Johnson EC, McCutcheon VV, Meyers JL, Schuckit M, Tischfield J, Wetherill L, Dick DM (2020) Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis. Addiction, 115(2), 337-346. PMID: 31659820; PMCID: PMC7034661; DOI: 10.1111/add.14815.

  14. Scarnati MS, Boreland AJ, Joel M, Hart RP, Pang ZP (2020) Differential sensitivity of human neurons carrying mu opioid receptor (MOR) N40D variants in response to ethanol. Alcohol, 87, 97-109. PMID: 32561311; PMCID: PMC7958146; DOI: 10.1016/j.alcohol.2020.05.004.

  15. Schuckit MA, Clarke DF, Smith TL, Mendoza LA (2020) Characteristics associated with denial of problem drinking among two generations of individuals with alcohol use disorders. Drug and Alcohol Dependence, 217, 108274. PMID: 32956977; PMCID: PMC7736262; DOI: 10.1016/j.drugalcdep.2020.108274.

  16. Subbie-Saenz de Viteri S, Pandey A, Pandey G, Kamarajan C, Smith R, Anokhin A, Bauer L, Bender A, Chan G, Dick D, Edenberg H, Kinreich S, Kramer J, Schuckit M, Zang Y, McCutcheon V, Bucholz K, Porjesz B, Meyers JL (2020) Pathways to post-traumatic stress disorder and alcohol dependence: Trauma, executive functioning, and family history of alcoholism in adolescents and young adults. Brain and Behavior, 10(11), e01789. PMID: 32990406; PMCID: PMC7667345; DOI: 10.1002/brb3.1789.

  17. Thapa KS, Chen AB, Lai D, Xuei X, Wetherill L, Tischfield JA, Liu Y, Edenberg HJ (2020) Identification of Functional Genetic Variants Associated With Alcohol Dependence and Related Phenotypes Using a High-Throughput Assay. Alcoholism: Clinical and Experimental Research, 44(12), 2494-2518. PMID: 33119910; PMCID: PMC7725989; DOI: 10.1111/acer.14492.

  18. Zhou H, Sealock JM, Sanchez-Roige S, Clarke TK, Levey DF, Cheng Z, Li B, Polimanti R, Kember RL, Smith RV, Thygesen JH, Morgan MY, Atkinson SR, Thursz MR, Nyegaard M, Mattheisen M, Borglum AD, Johnson EC, Justice AC, Palmer AA, McQuillin A, Davis LK, Edenberg HJ, Agrawal A, Kranzler HR, Gelernter J (2020) Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Nature Neuroscience, 23(7), 809-818. PMID: 32451486; PMCID: PMC7485556; DOI: 10.1038/s41593-020-0643-5.


2019 [25 Articles]

  1. Acion L, Kramer J, Liu X, Chan G, Langbehn D, Bucholz K, McCutcheon V, Hesselbrock V, Schuckit M, Dick D, Hesselbrock M, Kuperman S (2019) Reliability and validity of an internalizing symptom scale based on the adolescent and adult Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). American Journal of Drug and Alcohol Abuse, 45(2), 151-160. PMID: 29870277; PMCID: PMC6481182; DOI: 10.1080/00952990.2018.1476520.

  2. Chan G, Kramer JR, Schuckit MA, Hesselbrock V, Bucholz KK, Edenberg HJ, Acion L, Langbehn D, McCutcheon V, Nurnberger JI, Jr., Hesselbrock M, Porjesz B, Bierut L, Marenna BC, Cookman A, Kuperman S (2019) A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults. Alcoholism: Clinical and Experimental Research, 43(8), 1759-1768. PMID: 31141183; PMCID: PMC6685546; DOI: 10.1111/acer.14116.

  3. Cheng Z, Phokaew C, Chou YL, Lai D, Meyers JL, Agrawal A, Farrer LA, Kranzler HR, Gelernter J (2019) A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans. Translational Psychiatry, 9(1), 309. PMID: 31740666; PMCID: PMC6861240; DOI: 10.1038/s41398-019-0639-7.

  4. Cho SB, Su J, Kuo SI, Bucholz KK, Chan G, Edenberg HJ, McCutcheon VV, Schuckit MA, Kramer JR, Dick DM (2019) Positive and negative reinforcement are differentially associated with alcohol consumption as a function of alcohol dependence. Psychology of Addictive Behaviors, 33(1), 58-68. PMID: 30667237; PMCID: PMC6459181; DOI: 10.1037/adb0000436.

  5. Johnson EC, St Pierre CL, Meyers JL, Aliev F, McCutcheon VV, Lai D, Dick DM, Goate AM, Kramer J, Kuperman S, Nurnberger JI, Jr., Schuckit MA, Porjesz B, Edenberg HJ, Bucholz KK, Agrawal A (2019) The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample. Alcoholism: Clinical and Experimental Research, 43(6), 1113-1125. PMID: 30994927; PMCID: PMC6560626; DOI: 10.1111/acer.14064.

  6. Johnson EC, Tillman R, Aliev F, Meyers JL, Salvatore JE, Anokhin AP, Dick DM, Edenberg HJ, Kramer JR, Kuperman S, McCutcheon VV, Nurnberger JI, Jr., Porjesz B, Schuckit MA, Tischfield J, Bucholz KK, Agrawal A (2019) Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement. Addiction, 114(4), 687-697. PMID: 30474892; PMCID: PMC6411425; DOI: 10.1111/add.14512

  7. Kapoor M, Wang JC, Farris SP, Liu Y, McClintick J, Gupta I, Meyers JL, Bertelsen S, Chao M, Nurnberger J, Tischfield J, Harari O, Zeran L, Hesselbrock V, Bauer L, Raj T, Porjesz B, Agrawal A, Foroud T, Edenberg HJ, Mayfield RD, Goate A (2019) Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism. Translational Psychiatry, 9(1), 89. PMID: 30765688; PMCID: PMC6376002; DOI: 10.1038/s41398-019-0384-y.

  8. ***Kranzler HR, Zhou H, Kember RL, Vickers Smith R, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J (2019) Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. Nature Communications, 10(1), 1499. PMID: 30940813; PMCID: PMC6445072; DOI: 10.1038/s41467-019-09480-8.

  9. Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Jr., Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hariri AR, Edenberg HJ, Agrawal A, Bogdan R, Porjesz B, Goate AM, Foroud T (2019) Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. Genes, Brain and Behavior, 18(6), e12579. PMID: 31090166; PMCID: PMC6612573; DOI: 10.1111/gbb.12579.

  10. McClintick JN, Tischfield JA, Deng L, Kapoor M, Xuei X, Edenberg HJ (2019) Ethanol activates immune response in lymphoblastoid cells. Alcohol, 79, 81-91. PMID: 30639126; PMCID: PMC6616005; DOI: 10.1016/j.alcohol.2019.01.001.

  11. ***Meda SA, Narayanan B, Chorlian D, Meyers JL, Gelernter J, Hesselbrock V, Bauer L, Calhoun VD, Porjesz B, Pearlson GD (2019) Multivariate Analyses Reveal Biological Components Related to Neuronal Signaling and Immunity Mediating Electroencephalograms Abnormalities in Alcohol-Dependent Individuals from the Collaborative Study on the Genetics of Alcoholism Cohort. Alcoholism: Clinical and Experimental Research, 43(7), 1462-1477. PMID: 31009096; DOI: 10.1111/acer.14063.

  12. Meyers J, McCutcheon VV, Pandey AK, Kamarajan C, Subbie S, Chorlian D, Salvatore J, Pandey G, Almasy L, Anokhin A, Bauer L, Bender A, Dick DM, Edenberg HJ, Hesselbrock V, Kramer J, Kuperman S, Agrawal A, Bucholz K, Porjesz B (2019) Early Sexual Trauma Exposure and Neural Response Inhibition in Adolescence and Young Adults: Trajectories of Frontal Theta Oscillations During a Go/No-Go Task. Journal of the American Academy of Child and Adolescent Psychiatry, 58(2), 242-255 e242. PMID: 30738551; PMCID: PMC6537865; DOI: 10.1016/j.jaac.2018.07.905.

  13. Meyers JL, Chorlian DB, Johnson EC, Pandey AK, Kamarajan C, Salvatore JE, Aliev F, Subbie-Saenz de Viteri S, Zhang J, Chao M, Kapoor M, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Tischfield J, Goate A, Foroud T, Dick DM, Edenberg HJ, Agrawal A, Porjesz B (2019) Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood. Brain Sciences, 9(10), 280. PMID: 31627376; PMCID: PMC6826735; DOI: 10.3390/brainsci9100280.

  14. Meyers JL, Salvatore JE, Aliev F, Johnson EC, McCutcheon VV, Su J, Kuo SI, Lai D, Wetherill L, Wang JC, Chan G, Hesselbrock V, Foroud T, Bucholz KK, Edenberg HJ, Dick DM, Porjesz B, Agrawal A (2019) Psychosocial moderation of polygenic risk for cannabis involvement: the role of trauma exposure and frequency of religious service attendance. Translational Psychiatry, 9(1), 269. PMID: 31636251; PMCID: PMC6803671; DOI: 10.1038/s41398-019-0598-z.

  15. ***Mintz CM, Hartz SM, Borodovsky JT, Bierut LJ, Grucza RA (2019) Changes in associations of prescription opioid use disorder and illegal behaviors among adults in the United States from 2002 to 20. Addiction, 114(12), 2150-2159. PMID: 31033084; PMCID: PMC6819203; DOI: 10.1111/add.14638.

  16. Nurnberger JI, Jr., Yang Z, Zang Y, Acion L, Bierut L, Bucholz K, Chan G, Dick DM, Edenberg HJ, Kramer J, Kuperman S, Rice JP, Schuckit M (2019) Development of Alcohol Use Disorder as a Function of Age, Severity, and Comorbidity with Externalizing and Internalizing Disorders in a Young Adult Cohort. Journal of Psychiatry and Brain Science, 4, e190016. PMID: 31853508; PMCID: PMC6919651; DOI: 10.20900/jpbs.20190016.

  17. Palmer RHC, Brick LA, Chou YL, Agrawal A, McGeary JE, Heath AC, Bierut L, Keller MC, Johnson E, Hartz SM, Schuckit MA, Knopik VS (2019) The etiology of DSM-5 alcohol use disorder: Evidence of shared and non-shared additive genetic effects. Drug and Alcohol Dependence, 201, 147-154. PMID: 31229702; PMCID: PMC6929687; DOI: 10.1016/j.drugalcdep.2018.12.034.

  18. Polimanti R, Peterson RE, Ong JS, MacGregor S, Edwards AC, Clarke TK, Frank J, Gerring Z, Gillespie NA, Lind PA, Maes HH, Martin NG, Mbarek H, Medland SE, Streit F, Major Depressive Disorder Working Group of the Psychiatric Genomics C, Agrawal A, Edenberg HJ, Kendler KS, Lewis CM, Sullivan PF, Wray NR, Gelernter J, Derks EM (2019) Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. Psychological Medicine, 49(7), 1218-1226. PMID: 30929657; PMCID: PMC6565601; DOI: 10.1017/S0033291719000667.

  19. Rao X, Thapa KS, Chen AB, Lin H, Gao H, Reiter JL, Hargreaves KA, Ipe J, Lai D, Xuei X, Gu H, Kapoor M, Farris SP, Tischfield J, Foroud T, Goate AM, Skaar TC, Mayfield RD, Edenberg HJ, Liu Y (2019) Allele-Specific Expression and High-Throughput Reporter Assay Reveal Functional Variants in Human Brains with Alcohol Use Disorders. bioRxiv, 514992. DOI: 10.1101/514992.

  20. Scarnati MS, Halikere A, Pang ZP (2019) Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook. Alcohol, 74, 83-93. PMID: 30087005; PMCID: PMC6167197; DOI: 10.1016/j.alcohol.2018.03.008.

  21. Vaidya JG, Elmore AL, Wallace AL, Langbehn DR, Kramer JR, Kuperman S, O’Leary DS (2019) Association Between Age and Familial Risk for Alcoholism on Functional Connectivity in Adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 58(7), 692-701. PMID: 30768382; PMCID: PMC7428193; DOI: 10.1016/j.jaac.2018.12.008.

  22. Wang K, Chen X, Ward SC, Liu Y, Ouedraogo Y, Xu C, Cederbaum AI, Lu Y (2019) CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model. International Journal of Obesity (2005), 43(3), 475-486. PMID: 29568101; PMCID: PMC6102101; DOI: 10.1038/s41366-018-0037-x.

  23. Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI, Jr., Schuckit M, Scott DM, Taylor RE, Tischfield J, Porjesz B, Goate AM, Edenberg HJ, Foroud T, Bogdan R, Agrawal A (2019) ERRATUM: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. Genes, Brain and Behavior, 18(8), e12608. PMID: 31667958; DOI: 10.1111/gbb.12608.

  24. Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI, Jr., Schuckit M, Scott DM, Taylor RE, Tischfield J, Porjesz B, Goate AM, Edenberg HJ, Foroud T, Bogdan R, Agrawal A (2019) Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. Genes, Brain and Behavior, 18(6), e12580. PMID: 31099175; PMCID: PMC6726116; DOI: 10.1111/gbb.12580.

  25. ***Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, Schlogelhofer M, Sandor P, Barr CL, Grados M, Singer HS, Nothen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Luethvigsson P, Saemundsen E, Thorarensen O, Atzmon G, Barzilai N, Wagner M, Moessner R, Ophoff R, Pato CN, Pato MT, Knowles JA, Roffman JL, Smoller JW, Buckner RL, Willsey AJ, Tischfield JA, Heiman GA, Stefansson H, Stefansson K, Posthuma D, Cox NJ, Pauls DL, Freimer NB, Neale BM, Davis LK, Paschou P, Coppola G, Mathews CA, Scharf JM, Tourette Association of America International Consortium for Genetics tGdlTGRItTICGS, the Psychiatric Genomics Consortium Tourette Syndrome Working Group (2019) Interrogating the Genetic Determinants of Tourette’s Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. American Journal of Psychiatry, 176(3), 217-227. PMID: 30818990; PMCID: PMC6677250; DOI: 10.1176/appi.ajp.2018.18070857.


2018 [29 Articles]

  1. Agrawal A, Chou YL, Carey CE, Baranger DAA, Zhang B, Sherva R, Wetherill L, Kapoor M, Wang JC, Bertelsen S, Anokhin AP, Hesselbrock V, Kramer J, Lynskey MT, Meyers JL, Nurnberger JI, Rice JP, Tischfield J, Bierut LJ, Degenhardt L, Farrer LA, Gelernter J, Hariri AR, Heath AC, Kranzler HR, Madden PAF, Martin NG, Montgomery GW, Porjesz B, Wang T, Whitfield JB, Edenberg HJ, Foroud T, Goate AM, Bogdan R, Nelson EC (2018) Genome-wide association study identifies a novel locus for cannabis dependence. Molecular Psychiatry, 23(5), 1293-1302. PMID: 29112194; PMCID: PMC5938138; DOI: 10.1038/mp.2017.200.

  2. Aliev F, Salvatore JE, Agrawal A, Almasy L, Chan G, Edenberg HJ, Hesselbrock V, Kuperman S, Meyers J, Dick DM (2018) A Brief Critique of the TATES Procedure. Behavior Genetics, 48(2), 155-167. PMID: 29468442; PMCID: PMC6028780; DOI: 10.1007/s10519-018-9890-6.

  3. Chen LS, Hartz SM, Baker TB, Ma Y, N LS, Bierut LJ (2018) Use of polygenic risk scores of nicotine metabolism in predicting smoking behaviors. Pharmacogenomics, 19(18), 1383-1394. PMID: 30442082; PMCID: PMC6562697; DOI: 10.2217/pgs-2018-0081.

  4. Culverhouse RC, Saccone NL, Horton AC, Ma Y, Anstey KJ, Banaschewski T, Burmeister M, Cohen-Woods S, Etain B, Fisher HL, Goldman N, Guillaume S, Horwood J, Juhasz G, Lester KJ, Mandelli L, Middeldorp CM, Olie E, Villafuerte S, Air TM, Araya R, Bowes L, Burns R, Byrne EM, Coffey C, Coventry WL, Gawronski KAB, Glei D, Hatzimanolis A, Hottenga JJ, Jaussent I, Jawahar C, Jennen-Steinmetz C, Kramer JR, Lajnef M, Little K, Zu Schwabedissen HM, Nauck M, Nederhof E, Petschner P, Peyrot WJ, Schwahn C, Sinnamon G, Stacey D, Tian Y, Toben C, Van der Auwera S, Wainwright N, Wang JC, Willemsen G, Anderson IM, Arolt V, Aslund C, Bagdy G, Baune BT, Bellivier F, Boomsma DI, Courtet P, Dannlowski U, de Geus EJC, Deakin JFW, Easteal S, Eley T, Fergusson DM, Goate AM, Gonda X, Grabe HJ, Holzman C, Johnson EO, Kennedy M, Laucht M, Martin NG, Munafo MR, Nilsson KW, Oldehinkel AJ, Olsson CA, Ormel J, Otte C, Patton GC, Penninx B, Ritchie K, Sarchiapone M, Scheid JM, Serretti A, Smit JH, Stefanis NC, Surtees PG, Volzke H, Weinstein M, Whooley M, Nurnberger JI, Jr., Breslau N, Bierut LJ (2018) Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Molecular Psychiatry, 23(1), 133-142. PMID: 28373689; PMCID: PMC5628077; DOI: 10.1038/mp.2017.44.

  5. Dick DM (2018) Commentary for Special Issue of Prevention Science “Using Genetics in Prevention: Science Fiction or Science Fact?”. Prevention Science, 19(1), 101-108. PMID: 28735446; PMCID: PMC5754264; DOI: 10.1007/s11121-017-0828-7.

  6. Dick DM (2018) Mapping Risk from Genes to Behavior: The Enduring and Evolving Influence of Irving Gottesman’s Endophenotype Concept. Twin Research and Human Genetics, 21(4), 306-309. PMID: 30027865; DOI: 10.1017/thg.2018.35.

  7. Dick DM, Barr PB, Cho SB, Cooke ME, Kuo SI, Lewis TJ, Neale Z, Salvatore JE, Savage J, Su J (2018) Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the “Other” Next Steps. Genes, Brain and Behavior, 17(3), e12447. PMID: 29227573; PMCID: PMC5876087; DOI: 10.1111/gbb.12447.

  8. Edenberg HJ, McClintick JN (2018) Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review. Alcoholism: Clinical and Experimental Research, 42(12), 2281-2297. PMID: 30320893; PMCID: PMC6286250; DOI: 10.1111/acer.13904.

  9. Edwards AC, Deak JD, Gizer IR, Lai D, Chatzinakos C, Wilhelmsen KP, Lindsay J, Heron J, Hickman M, Webb BT, Bacanu SA, Foroud TM, Kendler KS, Dick DM, Schuckit MA (2018) Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity. Alcoholism: Clinical and Experimental Research, 42(12), 2349-2359. PMID: 30276832; PMCID: PMC6286211; DOI: 10.1111/acer.13896.

  10. Glasheen C, Johnson EO, Saccone NL, Lutz SM, Baker TB, McNeil DW, Marazita ML, Hokanson JE, Bierut LJ, Hancock DB (2018) Is the Fagerstrom test for nicotine dependence invariant across secular trends in smoking? A question for cross-birth cohort analysis of nicotine dependence. Drug and Alcohol Dependence, 185, 127-132. PMID: 29438887; PMCID: PMC5889733; DOI: 10.1016/j.drugalcdep.2017.12.013.

  11. Grucza RA, Sher KJ, Kerr WC, Krauss MJ, Lui CK, McDowell YE, Hartz S, Virdi G, Bierut LJ (2018) Trends in Adult Alcohol Use and Binge Drinking in the Early 21st-Century United States: A Meta-Analysis of 6 National Survey Series. Alcoholism: Clinical and Experimental Research, 42(10), 1939-1950. PMID: 30080258; PMCID: PMC6364977; DOI: 10.1111/acer.13859.

  12. Halikere A, Popova D, Hamod A, Swerdel MR, Moore JC, Tischfield JA, Hart RP, Pang ZP (2018) Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons. bioRxiv, 328898. DOI: 10.1101/328898.

  13. Hartz SM, Oehlert M, Horton AC, Grucza RA, Fisher SL, Culverhouse RC, Nelson KG, Sumerall SW, Neal PC, Regnier P, Chen G, Williams A, Bhattarai J, Evanoff B, Bierut LJ (2018) Daily Drinking Is Associated with Increased Mortality. Alcoholism: Clinical and Experimental Research, 42(11), 2246-2255. PMID: 30281161; PMCID: PMC6214719; DOI: 10.1111/acer.13886.

  14. Korhonen T, Sihvola E, Latvala A, Dick DM, Pulkkinen L, Nurnberger J, Rose RJ, Kaprio J (2018) Early-onset tobacco use and suicide-related behavior – A prospective study from adolescence to young adulthood. Addictive Behaviors, 79, 32-38. PMID: 29245024; PMCID: PMC5905715; DOI: 10.1016/j.addbeh.2017.12.008.

  15. Liu D, Zhang H (2018) Residuals and Diagnostics for Ordinal Regression Models: A Surrogate Approach. Journal of the American Statistical Association, 113(522), 845-854. PMID: 30220754; PMCID: PMC6133273; DOI: 10.1080/01621459.2017.1292915.

  16. McCutcheon VV, Agrawal A, Kuo SI, Su J, Dick DM, Meyers JL, Edenberg HJ, Nurnberger JI, Kramer JR, Kuperman S, Schuckit MA, Hesselbrock VM, Brooks A, Porjesz B, Bucholz KK (2018) Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families. Addiction, 113(2), 336-345. PMID: 28804966; PMCID: PMC5760304; DOI: 10.1111/add.14003.

  17. ***Miller ML, Ren Y, Szutorisz H, Warren NA, Tessereau C, Egervari G, Mlodnicka A, Kapoor M, Chaarani B, Morris CV, Schumann G, Garavan H, Goate AM, Bannon MJ, IMAGEN Consortium, Halperin JM, Hurd YL (2018) Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. Molecular Psychiatry, 23(5), 1328-1335. PMID: 28439100; PMCID: PMC5656565; DOI: 10.1038/mp.2017.80.

  18. Olfson E, Bloom J, Bertelsen S, Budde JP, Breslau N, Brooks A, Culverhouse R, Chan G, Chen LS, Chorlian D, Dick DM, Edenberg HJ, Hartz S, Hatsukami D, Hesselbrock VM, Johnson EO, Kramer JR, Kuperman S, Meyers JL, Nurnberger J, Porjesz B, Saccone NL, Schuckit MA, Stitzel J, Tischfield JA, Rice JP, Goate A, Bierut LJ (2018) CYP2A6 metabolism in the development of smoking behaviors in young adults. Addiction Biology, 23(1), 437-447. PMID: 28032407; PMCID: PMC5491369; DOI: 10.1111/adb.12477.

  19. Prytkova I, Goate A, Hart RP, Slesinger PA (2018) Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells? Alcoholism: Clinical and Experimental Research, 42(9), 1572-1590. PMID: 29897633; PMCID: PMC6120805; DOI: 10.1111/acer.13811.

  20. Salvatore JE, Dick DM (2018) Genetic influences on conduct disorder. Neurosci Biobehav Rev, 91, 91-101. PMID: 27350097; PMCID: PMC5183514; DOI: 10.1016/j.neubiorev.2016.06.034.

  21. Savage JE, Salvatore JE, Aliev F, Edwards AC, Hickman M, Kendler KS, Macleod J, Latvala A, Loukola A, Kaprio J, Rose RJ, Chan G, Hesselbrock V, Webb BT, Adkins A, Bigdeli TB, Riley BP, Dick DM (2018) Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples. Alcoholism: Clinical and Experimental Research, 42(3), 520-530. PMID: 29405378; PMCID: PMC5832589; DOI: 10.1111/acer.13589.

  22. Schuckit MA (2018) A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity. Alcoholism: Clinical and Experimental Research, 42(5), 822-835. PMID: 29623680; PMCID: PMC5916326; DOI: 10.1111/acer.13628.

  23. Schuckit MA, Smith TL, Danko G, Kramer J, Bucholz KK, McCutcheon V, Chan G, Kuperman S, Hesselbrock V, Dick DM, Hesselbrock M, Porjesz B, Edenberg HJ, Nureberger JI, Jr., Gregg M, Schoen L, Kawamura M, Mendoza LA (2018) A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism. Alcoholism: Clinical and Experimental Research, 42(9), 1704-1714. PMID: 29975427; PMCID: PMC6120781; DOI: 10.1111/acer.13810.

  24. Smit DJA, Wright MJ, Meyers JL, Martin NG, Ho YYW, Malone SM, Zhang J, Burwell SJ, Chorlian DB, de Geus EJC, Denys D, Hansell NK, Hottenga JJ, McGue M, van Beijsterveldt CEM, Jahanshad N, Thompson PM, Whelan CD, Medland SE, Porjesz B, Lacono WG, Boomsma DI (2018) Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity. Human Brain Mapping, 39(11), 4183-4195. PMID: 29947131; PMCID: PMC6179948; DOI: 10.1002/hbm.24238.

  25. Su J, Kuo SI, Aliev F, Guy MC, Derlan CL, Edenberg HJ, Nurnberger JI, Jr., Kramer JR, Bucholz KK, Salvatore JE, Dick DM (2018) Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective. Alcoholism: Clinical and Experimental Research, 42(9), 1783-1794. PMID: 29969154; PMCID: PMC6120770; DOI: 10.1111/acer.13827.

  26. Su J, Kuo SI, Bucholz KK, Edenberg HJ, Kramer JR, Schuckit M, Dick DM (2018) Understanding Mechanisms of Genetic Risk for Adolescent Internalizing and Externalizing Problems: The Mediating Role of Parenting and Personality. Twin Research and Human Genetics, 21(4), 310-321. PMID: 30027866; DOI: 10.1017/thg.2018.36.

  27. van der Vaart A, Meng X, Bowers MS, Batman AM, Aliev F, Farris SP, Hill JS, Green TA, Dick D, COGA Consortium, Wolstenholme JT, Miles MF (2018) Glycogen synthase kinase 3 beta regulates ethanol consumption and is a risk factor for alcohol dependence. Neuropsychopharmacology, 43(13), 2521-2531. PMID: 30188517; PMCID: PMC6224501; DOI: 10.1038/s41386-018-0202-x.

  28. Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, andMe Research T, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gabel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Mannisto S, Muller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Raikkonen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nothen MM, Palmer AA, Pedersen NL, Penninx B, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A (2018) Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience, 21(12), 1656-1669. PMID: 30482948; PMCID: PMC6430207; DOI: 10.1038/s41593-018-0275-1.

  29. Wetherill L, Foroud T, Goodlett C (2018) Meta-Analyses of Externalizing Disorders: Genetics or Prenatal Alcohol Exposure? Alcoholism: Clinical and Experimental Research, 42(1), 162-172. PMID: 29063614; PMCID: PMC5750073; DOI: 10.1111/acer.13535.


2017 [25 Articles]

  1. ***Adkins AE, Hack LM, Bigdeli TB, Williamson VS, McMichael GO, Mamdani M, Edwards AC, Aliev F, Chan RF, Bhandari P, Raabe RC, Alaimo JT, Blackwell GG, Moscati A, Poland RS, Rood B, Patterson DG, Walsh D, Collaborative Study of the Genetics of Alcoholism Consortium, Whitfield JB, Zhu G, Montgomery GW, Henders AK, Martin NG, Heath AC, Madden PAF, Frank J, Ridinger M, Wodarz N, Soyka M, Zill P, Ising M, Nothen MM, Kiefer F, Rietschel M, German Study of the Genetics of Addiction C, Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer LA, Maher BS, Prescott CA, Dick DM, Bacanu SA, Mathies LD, Davies AG, Vladimirov VI, Grotewiel M, Bowers MS, Bettinger JC, Webb BT, Miles MF, Kendler KS, Riley BP (2017) Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms. Alcoholism: Clinical and Experimental Research, 41(5), 911-928. PMID: 28226201; PMCID: PMC5404949; DOI: 10.1111/acer.13362.

  2. Agrawal A, Tillman R, Grucza RA, Nelson EC, McCutcheon VV, Few L, Conner KR, Lynskey MT, Dick DM, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI, Jr., Schuckit MA, Porjesz B, Bucholz KK (2017) Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism. Journal of Affective Disorders, 213, 96-104. PMID: 28213124; PMCID: PMC5434702; DOI: 10.1016/j.jad.2016.12.060.

  3. Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI, Jr., Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, Porjesz B, Dick DM, Hesselbrock V, Boerwinkle E, Southwick SM, Krystal JH, Weissman MM, Levinson DF, Potash JB, Gelernter J, Han S (2017) Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence. JAMA Psychiatry, 74(11), 1153-1160. PMID: 28813562; PMCID: PMC5710224; DOI: 10.1001/jamapsychiatry.2017.2269.

  4. Bucholz KK, McCutcheon VV, Agrawal A, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI, Jr., Salvatore JE, Schuckit MA, Bierut LJ, Foroud TM, Chan G, Hesselbrock M, Meyers JL, Edenberg HJ, Porjesz B (2017) Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study. Alcoholism: Clinical and Experimental Research, 41(2), 359-368. PMID: 28073157; PMCID: PMC5272776; DOI: 10.1111/acer.13293.

  5. Chartier KG, Hesselbrock MN, Hesselbrock VM (2017) Conclusion: Special issue on genetic and alcohol use disorder research with diverse racial/ethnic groups: Key findings and potential next steps. American Journal on Addictions, 26(5), 532-537. PMID: 28745446; PMCID: PMC5615400; DOI: 10.1111/ajad.12585.

  6. Chartier KG, Hesselbrock MN, Hesselbrock VM (2017) Introduction: Special issue on genetic research of alcohol use disorder in diverse racial/ethnic populations. American Journal on Addictions, 26(5), 422-423. PMID: 28672076; PMCID: PMC5600188; DOI: 10.1111/ajad.12576.

  7. Cho SB, Aliev F, Clark SL, Adkins AE, Edenberg HJ, Bucholz KK, Porjesz B, Dick DM (2017) Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders. Behavior Genetics, 47(4), 405-415. PMID: 28343281; PMCID: PMC5996973; DOI: 10.1007/s10519-017-9844-4.

  8. Chorlian DB, Rangaswamy M, Manz N, Meyers JL, Kang SJ, Kamarajan C, Pandey AK, Wang JC, Wetherill L, Edenberg H, Porjesz B (2017) Genetic correlates of the development of theta event related oscillations in adolescents and young adults. International Journal of Psychophysiology, 115, 24-39. PMID: 27847216; PMCID: PMC5456461; DOI: 10.1016/j.ijpsycho.2016.11.007.

  9. Dick DM (2017) Rethinking the Way We Do Research: The Benefits of Community-Engaged, Citizen Science Approaches and Nontraditional Collaborators. Alcoholism: Clinical and Experimental Research, 41(11), 1849-1856. PMID: 29028120; PMCID: PMC5679720; DOI: 10.1111/acer.13492.

  10. Dick DM, Barr P, Guy M, Nasim A, Scott D (2017) Review: Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications. American Journal on Addictions, 26(5), 486-493. PMID: 28240821; PMCID: PMC5884102; DOI: 10.1111/ajad.12495.

  11. Grant JD, Agrawal A, Werner KB, McCutcheon VV, Nelson EC, Madden PAF, Bucholz KK, Heath AC, Sartor CE (2017) Phenotypic and familial associations between childhood maltreatment and cannabis initiation and problems in young adult European-American and African-American women. Drug and Alcohol Dependence, 179, 146-152. PMID: 28779616; PMCID: PMC5599374; DOI: 10.1016/j.drugalcdep.2017.06.038.

  12. Hartz SM, Horton AC, Oehlert M, Carey CE, Agrawal A, Bogdan R, Chen LS, Hancock DB, Johnson EO, Pato CN, Pato MT, Rice JP, Bierut LJ (2017) Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia. Biological Psychiatry, 82(10), 709-715. PMID: 28739213; PMCID: PMC5643224; DOI: 10.1016/j.biopsych.2017.04.020.

  13. Jensen KP, Smith AH, Herman AI, Farrer LA, Kranzler HR, Sofuoglu M, Gelernter J (2017) A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. Molecular Psychiatry, 22(2), 242-249. PMID: 27067016; PMCID: PMC5390815; DOI: 10.1038/mp.2016.43.

  14. Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Edenberg HJ, Wetherill L, Schuckit M, Wang JC, Kuperman S, Kramer J, Tischfield JA, Porjesz B (2017) A KCNJ6 gene polymorphism modulates theta oscillations during reward processing. International Journal of Psychophysiology, 115, 13-23. PMID: 27993610; PMCID: PMC5392377; DOI: 10.1016/j.ijpsycho.2016.12.007.

  15. Kuperman S, Chan G, Kramer J, Wetherill L, Acion L, Edenberg HJ, Foroud TM, Nurnberger J, Jr., Agrawal A, Anokhin A, Brooks A, Hesselbrock V, Hesselbrock M, Schuckit M, Tischfield J, Liu X (2017) A GABRA2 polymorphism improves a model for prediction of drinking initiation. Alcohol, 63, 1-8. PMID: 28847377; PMCID: PMC5657392; DOI: 10.1016/j.alcohol.2017.03.003.

  16. Li JJ, Cho SB, Salvatore JE, Edenberg HJ, Agrawal A, Chorlian DB, Porjesz B, Hesselbrock V, Investigators C, Dick DM (2017) The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood. Alcoholism: Clinical and Experimental Research, 41(1), 65-75. PMID: 27991676; PMCID: PMC5205549; DOI: 10.1111/acer.13282.

  17. Mathies LD, Aliev F, Davies AG, Dick DM, Bettinger JC (2017) Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations. Alcoholism: Clinical and Experimental Research, 41(12), 2033-2040. PMID: 28981154; PMCID: PMC5711565; DOI: 10.1111/acer.13514.

  18. McCutcheon VV, Schuckit MA, Kramer JR, Chan G, Edenberg HJ, Smith TL, Bender AK, Hesselbrock V, Hesselbrock M, Bucholz KK (2017) Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands. Addiction, 112(11), 1909-1917. PMID: 28556494; PMCID: PMC5633502; DOI: 10.1111/add.13890.

  19. Meyers JL, Zhang J, Manz N, Rangaswamy M, Kamarajan C, Wetherill L, Chorlian DB, Kang SJ, Bauer L, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Jr., Tischfield J, Wang JC, Edenberg HJ, Goate A, Foroud T, Porjesz B (2017) A genome wide association study of fast beta EEG in families of European ancestry. International Journal of Psychophysiology, 115, 74-85. PMID: 28040410; PMCID: PMC5426060; DOI: 10.1016/j.ijpsycho.2016.12.008.

  20. Meyers JL, Zhang J, Wang JC, Su J, Kuo SI, Kapoor M, Wetherill L, Bertelsen S, Lai D, Salvatore JE, Kamarajan C, Chorlian D, Agrawal A, Almasy L, Bauer L, Bucholz KK, Chan G, Hesselbrock V, Koganti L, Kramer J, Kuperman S, Manz N, Pandey A, Seay M, Scott D, Taylor RE, Dick DM, Edenberg HJ, Goate A, Foroud T, Porjesz B (2017) An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. Molecular Psychiatry, 22(12), 1767-1775. PMID: 28070124; PMCID: PMC5503794; DOI: 10.1038/mp.2016.239.

  21. Nurnberger JI, Jr. (2017) A Genetic Locus Associated With Depression: The Iceberg Begins to Melt. Biological Psychiatry, 82(5), 304-305. PMID: 28781002; DOI: 10.1016/j.biopsych.2017.06.023.

  22. Owusu D, Pan Y, Xie C, Harirforoosh S, Wang KS (2017) Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension. Journal of Psychiatric Research, 84, 27-34. PMID: 27693979; DOI: 10.1016/j.jpsychires.2016.09.015.

  23. Schuckit MA, Smith TL, Danko G, Anthenelli R, Schoen L, Kawamura M, Kramer J, Dick DM, Neale Z, Kuperman S, McCutcheon V, Anokhin AP, Hesselbrock V, Hesselbrock M, Bucholz K (2017) A Prospective Comparison of How the Level of Response to Alcohol and Impulsivity Relate to Future DSM-IV Alcohol Problems in the COGA Youth Panel. Alcoholism: Clinical and Experimental Research, 41(7), 1329-1339. PMID: 28440866; PMCID: PMC5512427; DOI: 10.1111/acer.13407.

  24. Schuckit MA, Smith TL, Shafir A, Clausen P, Danko G, Goncalves PD, Anthenelli RM, Chan G, Kuperman S, Hesselbrock M, Hesselbrock V, Kramer J, Bucholz KK (2017) Predictors of Patterns of Alcohol-Related Blackouts Over Time in Youth From the Collaborative Study of the Genetics of Alcoholism: The Roles of Genetics and Cannabis. Journal of Studies on Alcohol and Drugs, 78(1), 39-48. PMID: 27936363; PMCID: PMC5148748; DOI: 10.15288/jsad.2017.78.39.

  25. Wang M, Huang J, Liu Y, Ma L, Potash JB, Han S (2017) COMBAT: A Combined Association Test for Genes Using Summary Statistics. Genetics, 207(3), 883-891. PMID: 28878002; PMCID: PMC5676236; DOI: 10.1534/genetics.117.300257.


2016 [13 Articles]

  1. Agrawal A, Edenberg HJ, Gelernter J (2016) Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics. Journal of Studies on Alcohol and Drugs, 77(5), 676-680. PMID: 27588522; PMCID: PMC5015465; DOI: 10.15288/jsad.2016.77.676.

  2. Carey CE, Agrawal A, Bucholz KK, Hartz SM, Lynskey MT, Nelson EC, Bierut LJ, Bogdan R (2016) Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement. Front Genet, 7, 149. PMID: 27574527; PMCID: PMC4983546; DOI: 10.3389/fgene.2016.00149.

  3. Chartier KG, Dick DM, Almasy L, Chan G, Aliev F, Schuckit MA, Scott DM, Kramer J, Bucholz KK, Bierut LJ, Nurnberger J, Jr., Porjesz B, Hesselbrock VM (2016) Interactions Between Alcohol Metabolism Genes and Religious Involvement in Association With Maximum Drinks and Alcohol Dependence Symptoms. Journal of Studies on Alcohol and Drugs, 77(3), 393-404. PMID: 27172571; PMCID: PMC4869897; DOI: 10.15288/jsad.2016.77.393.

  4. Clarke TK, Smith AH, Gelernter J, Kranzler HR, Farrer LA, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, Thomson PA, Porteous DJ, Deary IJ, McIntosh AM (2016) Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort. Addiction Biology, 21(2), 469-480. PMID: 25865819; PMCID: PMC4600406; DOI: 10.1111/adb.12245.

  5. Hao Y, Zhang P, Xuei X, Nakshatri H, Edenberg HJ, Li L, Liu Y (2016) Statistical modeling for sensitive detection of low-frequency single nucleotide variants. BMC Genomics, 17 Suppl 7, 514. PMID: 27556804; PMCID: PMC5001245; DOI: 10.1186/s12864-016-2905-x.

  6. Johnson EO, Hancock DB, Levy JL, Gaddis NC, Page GP, Glasheen C, Saccone NL, Bierut LJ, Kral AH (2016) KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. Addiction Biology, 21(6), 1217-1232. PMID: 26202629; PMCID: PMC4724343; DOI: 10.1111/adb.12286.

  7. Kapoor M, Chou YL, Edenberg HJ, Foroud T, Martin NG, Madden PA, Wang JC, Bertelsen S, Wetherill L, Brooks A, Chan G, Hesselbrock V, Kuperman S, Medland SE, Montgomery G, Tischfield J, Whitfield JB, Bierut LJ, Heath AC, Bucholz KK, Goate AM, Agrawal A (2016) Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures. Translational Psychiatry, 6(3), e761. PMID: 27003187; PMCID: PMC4872451; DOI: 10.1038/tp.2016.27.

  8. Nelson EC, Agrawal A, Heath AC, Bogdan R, Sherva R, Zhang B, Al-Hasani R, Bruchas MR, Chou YL, Demers CH, Carey CE, Conley ED, Fakira AK, Farrer LA, Goate A, Gordon S, Henders AK, Hesselbrock V, Kapoor M, Lynskey MT, Madden PA, Moron JA, Rice JP, Saccone NL, Schwab SG, Shand FL, Todorov AA, Wallace L, Wang T, Wray NR, Zhou X, Degenhardt L, Martin NG, Hariri AR, Kranzler HR, Gelernter J, Bierut LJ, Clark DJ, Montgomery GW (2016) Evidence of CNIH3 involvement in opioid dependence. Molecular Psychiatry, 21(5), 608-614. PMID: 26239289; PMCID: PMC4740268; DOI: 10.1038/mp.2015.102.

  9. Olfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ (2016) Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. Molecular Psychiatry, 21(5), 601-607. PMID: 26239294; PMCID: PMC4740321; DOI: 10.1038/mp.2015.105.

  10. Oni EN, Hart RP (2016) Bioinformatic Analysis of DNA Methylation in Neural Progenitor Cell Models of Alcohol Abuse. Current Pharmacology Reports, 2(5), 203-210. PMID: 27774408; PMCID: PMC5070667; DOI: 10.1007/s40495-016-0065-y.

  11. Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, Nelson EC, Reid MW, Robinson JD, Shen PH, Yang BZ, Andrews JA, Aveyard P, Beltcheva O, Brown SA, Cannon DS, Cichon S, Corley RP, Dahmen N, Degenhardt L, Foroud T, Gaebel W, Giegling I, Glatt SJ, Grucza RA, Hardin J, Hartmann AM, Heath AC, Herms S, Hodgkinson CA, Hoffmann P, Hops H, Huizinga D, Ising M, Johnson EO, Johnstone E, Kaneva RP, Kendler KS, Kiefer F, Kranzler HR, Krauter KS, Levran O, Lucae S, Lynskey MT, Maier W, Mann K, Martin NG, Mattheisen M, Montgomery GW, Muller-Myhsok B, Murphy MF, Neale MC, Nikolov MA, Nishita D, Nothen MM, Nurnberger J, Partonen T, Pergadia ML, Reynolds M, Ridinger M, Rose RJ, Rouvinen-Lagerstrom N, Scherbaum N, Schmal C, Soyka M, Stallings MC, Steffens M, Treutlein J, Tsuang M, Wall TL, Wodarz N, Yuferov V, Zill P, Bergen AW, Chen J, Cinciripini PM, Edenberg HJ, Ehringer MA, Ferrell RE, Gelernter J, Goldman D, Hewitt JK, Hopfer CJ, Iacono WG, Kaprio J, Kreek MJ, Kremensky IM, Madden PA, McGue M, Munafo MR, Philibert RA, Rietschel M, Roy A, Rujescu D, Saarikoski ST, Swan GE, Todorov AA, Vanyukov MM, Weiss RB, Bierut LJ, Saccone NL (2016) Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behavior Genetics, 46(2), 151-169. PMID: 26392368; PMCID: PMC4752855; DOI: 10.1007/s10519-015-9737-3.

  12. ***Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J (2016) Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry, 73(5), 472-480. PMID: 27028160; PMCID: PMC4974817; DOI: 10.1001/jamapsychiatry.2016.0036.

  13. ***van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppala I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Smith GD, Davies G, de Wit H, Ding J, Engelhardt BE, Eriksson JG, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Lehtimaki T, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Mbarek H, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Nivard MG, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Pulkki-Raback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Generation S, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Raikkonen K, Wilson JF, Keltikangas-Jarvinen L, Bierut LJ, Hettema JM, Grabe HJ, Penninx BW, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, Terracciano A, McGue M, Martin NG, Boomsma DI (2016) Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behavior Genetics, 46(2), 170-182. PMID: 26362575; PMCID: PMC4751159; DOI: 10.1007/s10519-015-9735-5.


2015 [30 Articles]

  1. Agrawal A, Lynskey MT, Kapoor M, Bucholz KK, Edenberg HJ, Schuckit M, Brooks A, Hesselbrock V, Kramer J, Saccone N, Tischfield J, Bierut LJ (2015) Are genetic variants for tobacco smoking associated with cannabis involvement? Drug and Alcohol Dependence, 150, 183-187. 16/j.d25770649; PMCID: PMC4443812; DOI: 10.1016/j.drugalcdep.2015.02.029.

  2. Aliev F, Wetherill L, Bierut L, Bucholz KK, Edenberg H, Foroud T, COGA Investigators, Dick DM (2015) Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample. Journal of Studies on Alcohol and Drugs, 76(1), 38-46. PMID: 25486392; PMCID: PMC4263779; DOI: 10.15288/jsad.2015.76.38.

  3. Blednov YA, Benavidez JM, Black M, Ferguson LB, Schoenhard GL, Goate AM, Edenberg HJ, Wetherill L, Hesselbrock V, Foroud T, Harris RA (2015) Peroxisome proliferator-activated receptors alpha and gamma are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcoholism: Clinical and Experimental Research, 39(1), 136-145. PMID: 25516156; PMCID: PMC4308472; DOI: 10.1111/acer.12610.

  4. Blustein EC, Munn-Chernoff MA, Grant JD, Sartor CE, Waldron M, Bucholz KK, Madden PA, Heath AC (2015) The Association of Low Parental Monitoring With Early Substance Use in European American and African American Adolescent Girls. Journal of Studies on Alcohol and Drugs, 76(6), 852-861. PMID: 26562593; PMCID: PMC4712655; DOI: 10.15288/jsad.2015.76.852.

  5. Carey CE, Agrawal A, Zhang B, Conley ED, Degenhardt L, Heath AC, Li D, Lynskey MT, Martin NG, Montgomery GW, Wang T, Bierut LJ, Hariri AR, Nelson EC, Bogdan R (2015) Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. Journal of Abnormal Psychology, 124(4), 860-877. PMID: 26595473; PMCID: PMC4700831; DOI: 10.1037/abn0000079.

  6. Chen LS, Baker TB, Jorenby D, Piper M, Saccone N, Johnson E, Breslau N, Hatsukami D, Carney RM, Bierut LJ (2015) Genetic variation (CHRNA5), medication (combination nicotine replacement therapy vs. varenicline), and smoking cessation. Drug and Alcohol Dependence, 154, 278-282. PMID: 26142345; PMCID: PMC4537319; DOI: 10.1016/j.drugalcdep.2015.06.022.

  7. Chorlian DB, Rangaswamy M, Manz N, Kamarajan C, Pandey AK, Edenberg H, Kuperman S, Porjesz B (2015) Gender modulates the development of theta event related oscillations in adolescents and young adults. Behavioural Brain Research, 292(1), 342-352. PMID: 26102560; PMCID: PMC4705839; DOI: 10.1016/j.bbr.2015.06.020.

  8. Dick DM, Agrawal A, Keller MC, Adkins A, Aliev F, Monroe S, Hewitt JK, Kendler KS, Sher KJ (2015) Candidate gene-environment interaction research: reflections and recommendations. Perspectives on Psychological Science, 10(1), 37-59. PMID: 25620996; PMCID: PMC4302784; DOI: 10.1177/1745691614556682.

  9. ***Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA (2015) Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biological Psychiatry, 77(5), 493-503. PMID: 25555482; PMCID: PMC4386684; DOI: 10.1016/j.biopsych.2014.08.025.

  10. Grucza RA, Hur M, Agrawal A, Krauss MJ, Plunk AD, Cavazos-Rehg PA, Chaloupka FJ, Bierut LJ (2015) A reexamination of medical marijuana policies in relation to suicide risk. Drug and Alcohol Dependence, 152, 68-72. PMID: 25979644; PMCID: PMC4459507; DOI: 10.1016/j.drugalcdep.2015.04.014.

  11. Hancock DB, Levy JL, Gaddis NC, Glasheen C, Saccone NL, Page GP, Bierut LJ, Kral AH, Johnson EO (2015) Replication of ZNF804A gene variant associations with risk of heroin addiction. Genes, Brain and Behavior,� PMID: 26382569; DOI: 10.1111/gbb.12254.

  12. Hancock DB, Levy JL, Gaddis NC, Glasheen C, Saccone NL, Page GP, Hulse GK, Wildenauer D, Kelty EA, Schwab SG, Degenhardt L, Martin NG, Montgomery GW, Attia J, Holliday EG, McEvoy M, Scott RJ, Bierut LJ, Nelson EC, Kral AH, Johnson EO (2015) Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1. Biological Psychiatry, 78(7), 474-484. PMID: 25744370; PMCID: PMC4519434; DOI: 10.1016/j.biopsych.2015.01.003.

  13. Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, Qaiser B, Sherva R, Steinberg S, Zink F, Stacey SN, Glasheen C, Chen J, Gu F, Frederiksen BN, Loukola A, Gudbjartsson DF, Bruske I, Landi MT, Bickeboller H, Madden P, Farrer L, Kaprio J, Kranzler HR, Gelernter J, Baker TB, Kraft P, Amos CI, Caporaso NE, Hokanson JE, Bierut LJ, Thorgeirsson TE, Johnson EO, Stefansson K (2015) Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence. Translational Psychiatry, 5, e651. PMID: 26440539; DOI: 10.1038/tp.2015.149.

  14. Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Anokhin AP, Bauer LO, Kuperman S, Kramer J, Bucholz KK, Schuckit MA, Hesselbrock VM, Porjesz B (2015) Deficient Event-Related Theta Oscillations in Individuals at Risk for Alcoholism: A Study of Reward Processing and Impulsivity Features. PLOS ONE, 10(11), e0142659. PMID: 26580209; PMCID: PMC4651365; DOI: 10.1371/journal.pone.0142659.

  15. Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Bauer LO, Hesselbrock VM, Schuckit MA, Kuperman S, Kramer J, Porjesz B (2015) Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. International Journal of Psychophysiology, 98(2 Pt 1), 182-200. PMID: 26388585; PMCID: PMC4898464; DOI: 10.1016/j.ijpsycho.2015.09.005.

  16. Kamarajan C, Porjesz B (2015) Advances in Electrophysiological Research. Alcohol Research: Current Reviews, 37(1), 53-87. PMID: 26259089; PMCID: PMC4476604; LINK.

  17. Kapoor M, Agrawal A (2015) Commentary: sex differences in the pathways to symptoms of alcohol use disorder: a study of opposite-sex twin pairs. Alcoholism: Clinical and Experimental Research, 39(6), 950-952. PMID: 25912665; DOI: 10.1111/acer.12736.

  18. Long EC, Aliev F, Wang JC, Edenberg HJ, Nurnberger J, Jr., Hesselbrock V, Porjesz B, Dick DM (2015) Further Analyses of Genetic Association Between GRM8 and Alcohol Dependence Symptoms Among Young Adults. Journal of Studies on Alcohol and Drugs, 76(3), 414-418. PMID: 25978827; PMCID: PMC4440299; DOI: 10.15288/jsad.2015.76.414.

  19. ***Machiela MJ, Zhou W, Sampson JN, Dean MC, Jacobs KB, Black A, Brinton LA, Chang IS, Chen C, Chen C, Chen K, Cook LS, Crous Bou M, De Vivo I, Doherty J, Friedenreich CM, Gaudet MM, Haiman CA, Hankinson SE, Hartge P, Henderson BE, Hong YC, Hosgood HD, 3rd, Hsiung CA, Hu W, Hunter DJ, Jessop L, Kim HN, Kim YH, Kim YT, Klein R, Kraft P, Lan Q, Lin D, Liu J, Le Marchand L, Liang X, Lissowska J, Lu L, Magliocco AM, Matsuo K, Olson SH, Orlow I, Park JY, Pooler L, Prescott J, Rastogi R, Risch HA, Schumacher F, Seow A, Setiawan VW, Shen H, Sheng X, Shin MH, Shu XO, VanDen Berg D, Wang JC, Wentzensen N, Wong MP, Wu C, Wu T, Wu YL, Xia L, Yang HP, Yang PC, Zheng W, Zhou B, Abnet CC, Albanes D, Aldrich MC, Amos C, Amundadottir LT, Berndt SI, Blot WJ, Bock CH, Bracci PM, Burdett L, Buring JE, Butler MA, Carreon T, Chatterjee N, Chung CC, Cook MB, Cullen M, Davis FG, Ding T, Duell EJ, Epstein CG, Fan JH, Figueroa JD, Fraumeni JF, Jr., Freedman ND, Fuchs CS, Gao YT, Gapstur SM, Patino-Garcia A, Garcia-Closas M, Gaziano JM, Giles GG, Gillanders EM, Giovannucci EL, Goldin L, Goldstein AM, Greene MH, Hallmans G, Harris CC, Henriksson R, Holly EA, Hoover RN, Hu N, Hutchinson A, Jenab M, Johansen C, Khaw KT, Koh WP, Kolonel LN, Kooperberg C, Krogh V, Kurtz RC, LaCroix A, Landgren A, Landi MT, Li D, Liao LM, Malats N, McGlynn KA, McNeill LH, McWilliams RR, Melin BS, Mirabello L, Peplonska B, Peters U, Petersen GM, Prokunina-Olsson L, Purdue M, Qiao YL, Rabe KG, Rajaraman P, Real FX, Riboli E, Rodriguez-Santiago B, Rothman N, Ruder AM, Savage SA, Schwartz AG, Schwartz KL, Sesso HD, Severi G, Silverman DT, Spitz MR, Stevens VL, Stolzenberg-Solomon R, Stram D, Tang ZZ, Taylor PR, Teras LR, Tobias GS, Viswanathan K, Wacholder S, Wang Z, Weinstein SJ, Wheeler W, White E, Wiencke JK, Wolpin BM, Wu X, Wunder JS, Yu K, Zanetti KA, Zeleniuch-Jacquotte A, Ziegler RG, de Andrade M, Barnes KC, Beaty TH, Bierut LJ, Desch KC, Doheny KF, Feenstra B, Ginsburg D, Heit JA, Kang JH, Laurie CA, Li JZ, Lowe WL, Marazita ML, Melbye M, Mirel DB, Murray JC, Nelson SC, Pasquale LR, Rice K, Wiggs JL, Wise A, Tucker M, Perez-Jurado LA, Laurie CC, Caporaso NE, Yeager M, Chanock SJ (2015) Characterization of large structural genetic mosaicism in human autosomes. American Journal of Human Genetics, 96(3), 487-497. PMID: 25748358; PMCID: PMC4375431; DOI: 10.1016/j.ajhg.2015.01.011.

  20. Mamdani M, Williamson V, McMichael GO, Blevins T, Aliev F, Adkins A, Hack L, Bigdeli T, A DvdV, Web BT, Bacanu SA, Kalsi G, COGA Consortium, Kendler KS, Miles MF, Dick D, Riley BP, Dumur C, Vladimirov VI (2015) Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence. PLOS ONE, 10(9), e0137671. PMID: 26381263; PMCID: PMC4575063; DOI: 10.1371/journal.pone.0137671.

  21. Ohannessian CM, Finan LJ, Schulz J, Hesselbrock V (2015) A Long-Term Longitudinal Examination of the Effect of Early Onset of Alcohol and Drug Use on Later Alcohol Abuse. Substance Abuse, 0. PMID: 25671782; PMCID: PMC4532648; DOI: 10.1080/08897077.2014.989353.

  22. Sadler B, Haller G, Edenberg H, Tischfield J, Brooks A, Kramer J, Schuckit M, Nurnberger J, Goate A (2015) Positive Selection on Loci Associated with Drug and Alcohol Dependence. PLOS ONE, 10(8), e0134393. PMID: 26270548; PMCID: PMC4536217; DOI: 10.1371/journal.pone.0134393.

  23. Salvatore JE, Aliev F, Bucholz K, Agrawal A, Hesselbrock V, Hesselbrock M, Bauer L, Kuperman S, Schuckit MA, Kramer J, Edenberg HJ, Foroud TM, Dick DM (2015) Polygenic risk for externalizing disorders: Gene-by-development and gene-by-environment effects in adolescents and young adults. Clin Psychol Sci, 3(2), 189-201. PMID: 25821660; PMCID: PMC4371857; DOI: 10.1177/2167702614534211.

  24. Salvatore JE, Dick DM (2015) Gene-Environment Interplay: Where We Are, Where We Are Going. Journal of Marriage and Family, 77(2), 344-350. PMID: 25838604; PMCID: PMC4378262; DOI: 10.1111/jomf.12164.

  25. Salvatore JE, Edwards AC, McClintick JN, Bigdeli TB, Adkins A, Aliev F, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Tischfield JA, Xuei X, Dick DM (2015) Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior. Translational Psychiatry, 5(4), e558. PMID: 25918995; PMCID: PMC4462601; DOI: 10.1038/tp.2015.36.

  26. Salvatore JE, Gottesman, II, Dick DM (2015) Endophenotypes for Alcohol Use Disorder: An Update on the Field. Curr Addict Rep, 2(1), 76-90. PMID: 26236574; PMCID: PMC4520241; DOI: 10.1007/s40429-015-0046-y.

  27. Salvatore JE, Meyers JL, Yan J, Aliev F, Lansford JE, Pettit GS, Bates JE, Dodge KA, Rose RJ, Pulkkinen L, Kaprio J, Dick DM (2015) Intergenerational continuity in parents’ and adolescents’ externalizing problems: The role of life events and their interaction with GABRA2. Journal of Abnormal Psychology, 124(3), 709-728. PMID: 26075969; PMCID: PMC4573794; DOI: 10.1037/abn0000066.

  28. Wetherill L, Agrawal A, Kapoor M, Bertelsen S, Bierut LJ, Brooks A, Dick D, Hesselbrock M, Hesselbrock V, Koller DL, Le N, Nurnberger JI, Jr., Salvatore JE, Schuckit M, Tischfield JA, Wang JC, Xuei X, Edenberg HJ, Porjesz B, Bucholz K, Goate AM, Foroud T (2015) Association of substance dependence phenotypes in the COGA sample. Addiction Biology, 20(3), 617-627. PMID: 24832863; PMCID: PMC4233207; DOI: 10.1111/adb.12153.

  29. ***Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J (2015) Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcoholism: Clinical and Experimental Research, 39(7), 1137-1147. PMID: 26036284; DOI: 10.1111/acer.12751.

  30. ***Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert DL, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grunblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosario MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ, Pauls DL (2015) Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette’s syndrome and OCD. American Journal of Psychiatry, 172(1), 82-93. PMID: 25158072; PMCID: PMC4282594; DOI: 10.1176/appi.ajp.2014.13101306.


2014 [28 Articles]

  1. Agrawal A, Lynskey MT, Bucholz KK, Kapoor M, Almasy L, Dick DM, Edenberg HJ, Foroud T, Goate A, Hancock DB, Hartz S, Johnson EO, Hesselbrock V, Kramer JR, Kuperman S, Nurnberger JI, Jr., Schuckit M, Bierut LJ (2014) DSM-5 cannabis use disorder: A phenotypic and genomic perspective. Drug and Alcohol Dependence, 134, 362-369. PMID: 24315570; DOI: 10.1016/j.drugalcdep.2013.11.008.

  2. Conner KR, Bossarte RM, Lu N, Kaukeinen K, Chan G, Wyman P, Tu XM, Goldston DB, Houston RJ, Bucholz KK, Hesselbrock VM (2014) Parent and child psychopathology and suicide attempts among children of parents with alcohol use disorder. Archives of Suicide Research, 18(2), 117-130. PMID: 24716789; PMCID: PMC4059391; DOI: 10.1080/13811118.2013.826154.

  3. Conner KR, Wyman P, Goldston DB, Bossarte RM, Lu N, Kaukeinen K, Tu XM, Houston RJ, Lamis DA, Chan G, Bucholz KK, Hesselbrock VM (2014) Two Studies of Connectedness to Parents and Suicidal Thoughts and Behavior in Children and Adolescents. Journal of Clinical Child and Adolescent Psychology, 1-12. PMID: 25310350; DOI: 10.1080/15374416.2014.952009.

  4. Culverhouse RC, Johnson EO, Breslau N, Hatsukami DK, Sadler B, Brooks AI, Hesselbrock VM, Schuckit MA, Tischfield JA, Goate AM, Saccone NL, Bierut LJ (2014) Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans. Addiction, 109(5), 814-822. PMID: 24401102; PMCID: PMC3984604; DOI: 10.1111/add.12478.

  5. Dick DM, Cho SB, Latendresse SJ, Aliev F, Nurnberger JI, Jr., Edenberg HJ, Schuckit M, Hesselbrock VM, Porjesz B, Bucholz K, Wang JC, Goate A, Kramer JR, Kuperman S (2014) Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. Addiction Biology, 19(6), 1055-1064. PMID: 23692184; PMCID: PMC3783626; DOI: 10.1111/adb.12066.

  6. Edenberg HJ, Foroud T (2014) Genetics of alcoholism. Handbook of Clinical Neurology, 125, 561-571. PMID: 25307596; DOI: 10.1016/B978-0-444-62619-6.00032-X.

  7. ***Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA (2014) Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Molecular Psychiatry, 19(1), 41-49. PMID: 24166409; PMCID: PMC4165335; DOI: 10.1038/mp.2013.145.

  8. ***Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA (2014) Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biological Psychiatry, 76(1), 66-74. PMID: 24143882; PMCID: PMC3992201; DOI: 10.1016/j.biopsych.2013.08.034.

  9. ***Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer L (2014) Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. Molecular Psychiatry, 19(6), 717-723. PMID: 23958962; PMCID: PMC3865158; DOI: 10.1038/mp.2013.99.

  10. Glass JE, Williams EC, Bucholz KK (2014) Psychiatric comorbidity and perceived alcohol stigma in a nationally representative sample of individuals with DSM-5 alcohol use disorder. Alcoholism: Clinical and Experimental Research, 38(6), 1697-1705. PMID: 24848495; PMCID: PMC4059348; DOI: 10.1111/acer.12422.

  11. Haller G, Kapoor M, Budde J, Xuei X, Edenberg H, Nurnberger J, Kramer J, Brooks A, Tischfield J, Almasy L, Agrawal A, Bucholz K, Rice J, Saccone N, Bierut L, Goate A (2014) Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence. Human Molecular Genetics, 23(3), 810-819. PMID: 24057674; PMCID: PMC3888263; DOI: 10.1093/hmg/ddt463.

  12. Hartz SM, Bierut LJ, Pato MT (2014) In reply. JAMA Psychiatry, 71(8), 969. PMID: 25102905; DOI: 10.1001/jamapsychiatry.2014.707.

  13. Hartz SM, Pato CN, Medeiros H, Cavazos-Rehg P, Sobell JL, Knowles JA, Bierut LJ, Pato MT (2014) Comorbidity of severe psychotic disorders with measures of substance use. JAMA Psychiatry, 71(3), 248-254. PMID: 24382686; PMCID: PMC4060740; DOI: 10.1001/jamapsychiatry.2013.3726.

  14. Iyer-Eimerbrink PA, Nurnberger JI, Jr. (2014) Genetics of alcoholism. Current Psychiatry Reports, 16(12), 518. PMID: 25399692; DOI: 10.1007/s11920-014-0518-0.

  15. Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Almasy L, Bucholz K, Dick DM, Harari O, Xiaoling X, Hesselbrock V, Kramer J, Nurnberger JI, Jr., Rice J, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A (2014) Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. Drug and Alcohol Dependence, 142, 56-62. PMID: 24962325; PMCID: PMC4127128; DOI: 10.1016/j.drugalcdep.2014.05.023.

  16. McClintick JN, Brooks AI, Deng L, Liang L, Wang JC, Kapoor M, Xuei X, Foroud T, Tischfield JA, Edenberg HJ (2014) Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression. Alcohol, 48(6), 603-610. PMID: 25129674; PMCID: PMC4730944; DOI: 10.1016/j.alcohol.2014.07.004.

  17. McCutcheon VV, Kramer JR, Edenberg HJ, Nurnberger JI, Kuperman S, Schuckit MA, Heath AC, Bucholz KK (2014) Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample. Alcoholism: Clinical and Experimental Research, 38(7), 2015-2023. PMID: 24942361; PMCID: PMC4107016; DOI: 10.1111/acer.12434.

  18. ***McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O’Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM (2014) Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry, 53(8), 910-919. PMID: 25062598; PMCID: PMC4218748; DOI: 10.1016/j.jaac.2014.04.022.

  19. Olfson E, Edenberg HJ, Nurnberger J, Jr., Agrawal A, Bucholz KK, Almasy LA, Chorlian D, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, Schuckit MA, Tischfield JA, Wang JC, Wetherill L, Foroud TM, Rice J, Goate A, Bierut LJ (2014) An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction. Alcoholism: Clinical and Experimental Research, 38(10), 2541-2549. PMID: 25257461; PMCID: PMC4256939; DOI: 10.1111/acer.12524.

  20. ***Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tsernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Zhao JH, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Collee JM, Couch FJ, Couper D, Coveillo AD, Cox A, Czene K, D’Adamo A P, Smith GD, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, Garcia-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Guenel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, Magi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylkas K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, Stockl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, Volzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, Australian Ovarian Cancer S, Network G, kConFab, LifeLines Cohort S, InterAct C, Early Growth Genetics C, Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, Jarvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, Sorensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK (2014) Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature, 514(7520), 92-97. PMID: 25231870; PMCID: PMC4185210; DOI: 10.1038/nature13545.

  21. Peterson RE, Maes HH, Lin P, Kramer JR, Hesselbrock VM, Bauer LO, Nurnberger JI, Jr., Edenberg HJ, Dick DM, Webb BT (2014) On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis. BMC Genomics, 15(1), 368. PMID: 24884913; PMCID: PMC4035084; DOI: 10.1186/1471-2164-15-368.

  22. Rangaswamy M, Porjesz B (2014) Understanding alcohol use disorders with neuroelectrophysiology. Handbook of Clinical Neurology, 125, 383-414. PMID: 25307587; PMCID: PMC4331067; DOI: 10.1016/B978-0-444-62619-6.00023-9.

  23. Sadler B, Haller G, Agrawal A, Culverhouse R, Bucholz K, Brooks A, Tischfield J, Johnson EO, Edenberg H, Schuckit M, Saccone N, Bierut L, Goate A (2014) Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy. Scientific Reports, 4, 4497. PMID: 24675634; PMCID: PMC4894386; DOI: 10.1038/srep04497.

  24. Schuckit MA, Smith TL, Danko GP, Bucholz KK, Agrawal A, Dick DM, Nurnberger JI, Kramer J, Hesselbrock M, Saunders G, Hesselbrock V (2014) Predictors of subgroups based on maximum drinks per occasion over six years for 833 adolescents and young adults in COGA. Journal of Studies on Alcohol and Drugs, 75(1), 24-34. PMID: 24411794; PMCID: PMC3893632; DOI: 10.15288/jsad.2014.75.24.

  25. ***van den Berg SM, de Moor MH, McGue M, Pettersson E, Terracciano A, Verweij KJ, Amin N, Derringer J, Esko T, van Grootheest G, Hansell NK, Huffman J, Konte B, Lahti J, Luciano M, Matteson LK, Viktorin A, Wouda J, Agrawal A, Allik J, Bierut L, Broms U, Campbell H, Smith GD, Eriksson JG, Ferrucci L, Franke B, Fox JP, de Geus EJ, Giegling I, Gow AJ, Grucza R, Hartmann AM, Heath AC, Heikkila K, Iacono WG, Janzing J, Jokela M, Kiemeney L, Lehtimaki T, Madden PA, Magnusson PK, Northstone K, Nutile T, Ouwens KG, Palotie A, Pattie A, Pesonen AK, Polasek O, Pulkkinen L, Pulkki-Raback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Seppala I, Slutske WS, Smyth DC, Sorice R, Starr JM, Sutin AR, Tanaka T, Verhagen J, Vermeulen S, Vuoksimaa E, Widen E, Willemsen G, Wright MJ, Zgaga L, Rujescu D, Metspalu A, Wilson JF, Ciullo M, Hayward C, Rudan I, Deary IJ, Raikkonen K, Arias Vasquez A, Costa PT, Keltikangas-Jarvinen L, van Duijn CM, Penninx BW, Krueger RF, Evans DM, Kaprio J, Pedersen NL, Martin NG, Boomsma DI (2014) Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. Behavior Genetics, 44(4), 295-313. PMID: 24828478; PMCID: PMC4057636; DOI: 10.1007/s10519-014-9654-x.

  26. Wang JC, Kapoor M, Goate AM (2014) Association of genes involved in calcium and potassium pathways with opioid dependence. Biological Psychiatry, 76(1), 6-7. PMID: 24925890; DOI: 10.1016/j.biopsych.2014.04.012.

  27. Wetherill L, Kapoor M, Agrawal A, Bucholz K, Koller D, Bertelsen SE, Le N, Wang JC, Almasy L, Hesselbrock V, Kramer J, Nurnberger JI, Jr., Schuckit M, Tischfield JA, Xuei X, Porjesz B, Edenberg HJ, Goate AM, Foroud T (2014) Family-based association analysis of alcohol dependence criteria and severity. Alcoholism: Clinical and Experimental Research, 38(2), 354-366. PMID: 24015780; PMCID: PMC3946798; DOI: 10.1111/acer.12251.

  28. Yan J, Aliev F, Webb BT, Kendler KS, Williamson VS, Edenberg HJ, Agrawal A, Kos MZ, Almasy L, Nurnberger JI, Jr., Schuckit MA, Kramer JR, Rice JP, Kuperman S, Goate AM, Tischfield JA, Porjesz B, Dick DM (2014) Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. Addiction Biology, 19(4), 708-721. PMID: 23362995; PMCID: PMC3664249; DOI: 10.1111/adb.12035.


2013 [20 Articles]

  1. Agrawal A, Wetherill L, Bucholz KK, Kramer J, Kuperman S, Lynskey MT, Nurnberger JI, Jr., Schuckit M, Tischfield JA, Edenberg HJ, Foroud T, Bierut LJ (2013) Genetic influences on craving for alcohol. Addictive Behaviors, 38(2), 1501-1508. PMID: 22481050; PMCID: PMC3394913; DOI: 10.1016/j.addbeh.2012.03.021.

  2. Chorlian DB, Rangaswamy M, Manz N, Wang JC, Dick D, Almasy L, Bauer L, Bucholz K, Foroud T, Hesselbrock V, Kang SJ, Kramer J, Kuperman S, Nurnberger J, Jr., Rice J, Schuckit M, Tischfield J, Edenberg HJ, Goate A, Bierut L, Porjesz B (2013) Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. Behavior Genetics, 43(5), 386-401. PMID: 23963516; PMCID: PMC4110722; DOI: 10.1007/s10519-013-9604-z.

  3. Culverhouse RC, Bowes L, Breslau N, Nurnberger JI, Jr., Burmeister M, Fergusson DM, Munafo M, Saccone NL, Bierut LJ, 5-HTTLPR Stress and Depression Consortium (2013) Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC Psychiatry, 13, 304. PMID: 24219410; PMCID: PMC3840571; DOI: 10.1186/1471-244X-13-304.

  4. ***Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Mesa Restrepo SC, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosario MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Valencia Duarte AV, Vallada H, Van Nieuwerburgh F, Veenstra-Vanderweele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ, Scharf JM (2013) Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genetics, 9(10), e1003864. PMID: 24204291; PMCID: PMC3812053; DOI: 10.1371/journal.pgen.1003864.

  5. Derringer J, Krueger RF, Dick DM, Agrawal A, Bucholz KK, Foroud T, Grucza RA, Hesselbrock MN, Hesselbrock V, Kramer J, Nurnberger JI, Jr., Schuckit M, Bierut LJ, Iacono WG, McGue M (2013) Measurement invariance of DSM-IV alcohol, marijuana and cocaine dependence between community-sampled and clinically overselected studies. Addiction, 108(10), 1767-1776. PMID: 23651171; PMCID: PMC3742679; DOI: 10.1111/add.12187.

  6. Dick DM, Aliev F, Latendresse S, Porjesz B, Schuckit M, Rangaswamy M, Hesselbrock V, Edenberg H, Nurnberger J, Agrawal A, Bierut L, Wang J, Bucholz K, Kuperman S, Kramer J (2013) How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity. Twin Research and Human Genetics, 16(3), 661-669. PMID: 23561058; PMCID: PMC3663593; DOI: 10.1017/thg.2013.20.

  7. Edenberg HJ, Foroud T (2013) Genetics and alcoholism. Nature Reviews: Gastroenterology & Hepatology, 10(8), 487-494. PMID: 23712313; PMCID: PMC4056340; DOI: 10.1038/nrgastro.2013.86.

  8. Fernandez-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, McArdle PF, Yerges-Armstrong LM, Elks CE, Strachan DP, Kutalik Z, Vollenweider P, Feenstra B, Boyd HA, Metspalu A, Mihailov E, Broer L, Zillikens MC, Oostra B, van Duijn CM, Lunetta KL, Perry JR, Murray A, Koller DL, Lai D, Corre T, Toniolo D, Albrecht E, Stockl D, Grallert H, Gieger C, Hayward C, Polasek O, Rudan I, Wilson JF, He C, Kraft P, Hu FB, Hunter DJ, Hottenga JJ, Willemsen G, Boomsma DI, Byrne EM, Martin NG, Montgomery GW, Warrington NM, Pennell CE, Stolk L, Visser JA, Hofman A, Uitterlinden AG, Rivadeneira F, Lin P, Fisher SL, Bierut LJ, Crisponi L, Porcu E, Mangino M, Zhai G, Spector TD, Buring JE, Rose LM, Ridker PM, Poole C, Hirschhorn JN, Murabito JM, Chasman DI, Widen E, North KE, Ong KK, Franceschini N (2013) Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. American Journal of Epidemiology, 178(3), 451-460. PMID: 23558354; PMCID: PMC3816344; DOI: 10.1093/aje/kws473.

  9. Hashimoto E, Riederer PF, Hesselbrock VM, Hesselbrock MN, Mann K, Ukai W, Sohma H, Thibaut F, Schuckit MA, Saito T (2013) Consensus paper of the WFSBP task force on biological markers: biological markers for alcoholism. World Journal of Biological Psychiatry, 14(8), 549-564. PMID: 24236956; DOI: 10.3109/15622975.2013.838302.

  10. Hesselbrock MN, Hesselbrock VM, Chartier KG (2013) Genetics of alcohol dependence and social work research: do they mix? Soc Work Public Health, 28(3-4), 178-193. PMID: 23731413; DOI: 10.1080/19371918.2013.758999.

  11. Johnson EO, Hancock DB, Levy JL, Gaddis NC, Saccone NL, Bierut LJ, Page GP (2013) Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy. Human Genetics, 132(5), 509-522. PMID: 23334152; PMCID: PMC3628082; DOI: 10.1007/s00439-013-1266-7.

  12. Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Bucholz K, Dick D, Harari O, Hesselbrock V, Kramer J, Nurnberger JI, Jr., Rice J, Saccone N, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A (2013) A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. Human Genetics, 132(10), 1141-1151. PMID: 23743675; PMCID: PMC3776011; DOI: 10.1007/s00439-013-1318-z.

  13. Kos MZ, Yan J, Dick DM, Agrawal A, Bucholz KK, Rice JP, Johnson EO, Schuckit M, Kuperman S, Kramer J, Goate AM, Tischfield JA, Foroud T, Nurnberger J, Jr., Hesselbrock V, Porjesz B, Bierut LJ, Edenberg HJ, Almasy L (2013) Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. Genes, Brain and Behavior, 12(5), 532-542. PMID: 23607416; PMCID: PMC3709451; DOI: 10.1111/gbb.12043.

  14. Kuperman S, Chan G, Kramer JR, Wetherill L, Bucholz KK, Dick D, Hesselbrock V, Porjesz B, Rangaswamy M, Schuckit M (2013) A model to determine the likely age of an adolescent’s first drink of alcohol. Pediatrics, 131(2), 242-248. PMID: 23296431; PMCID: PMC3557403; DOI: 10.1542/peds.2012-0880.

  15. McClintick JN, Xuei X, Tischfield JA, Goate A, Foroud T, Wetherill L, Ehringer MA, Edenberg HJ (2013) Stress-response pathways are altered in the hippocampus of chronic alcoholics. Alcohol, 47(7), 505-515. PMID: 23981442; PMCID: PMC3836826; DOI: 10.1016/j.alcohol.2013.07.002.

  16. Perry BL, Pescosolido BA, Bucholz K, Edenberg H, Kramer J, Kuperman S, Schuckit MA, Nurnberger JI, Jr. (2013) Gender-specific gene-environment interaction in alcohol dependence: the impact of daily life events and GABRA2. Behavior Genetics, 43(5), 402-414. PMID: 23974430; PMCID: PMC4441044; DOI: 10.1007/s10519-013-9607-9.

  17. ***Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrio GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A, North American Brain Expression C, Hardy J, Database UKHBE, Strengman E, Ophoff RA, Wagner M, Moessner R, Mirel DB, Posthuma D, Sabatti C, Eskin E, Conti DV, Knowles JA, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon WM, Freimer NB, Cox NJ, Pauls DL (2013) Genome-wide association study of Tourette’s syndrome. Molecular Psychiatry, 18(6), 721-728. PMID: 22889924; PMCID: PMC3605224; DOI: 10.1038/mp.2012.69.

  18. Wang JC, Foroud T, Hinrichs AL, Le NX, Bertelsen S, Budde JP, Harari O, Koller DL, Wetherill L, Agrawal A, Almasy L, Brooks AI, Bucholz K, Dick D, Hesselbrock V, Johnson EO, Kang S, Kapoor M, Kramer J, Kuperman S, Madden PA, Manz N, Martin NG, McClintick JN, Montgomery GW, Nurnberger JI, Jr., Rangaswamy M, Rice J, Schuckit M, Tischfield JA, Whitfield JB, Xuei X, Porjesz B, Heath AC, Edenberg HJ, Bierut LJ, Goate AM (2013) A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. Molecular Psychiatry, 18(11), 1218-1224. PMID: 23089632; PMCID: PMC3752321; DOI: 10.1038/mp.2012.143.

  19. Wang JC, Spiegel N, Bertelsen S, Le N, McKenna N, Budde JP, Harari O, Kapoor M, Brooks A, Hancock D, Tischfield J, Foroud T, Bierut LJ, Steinbach JH, Edenberg HJ, Traynor BJ, Goate AM (2013) Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry. PLOS ONE, 8(11), e80204. PMID: 24303001; PMCID: PMC3841173; DOI: 10.1371/journal.pone.0080204.

  20. Zhang Z, Wang JC, Howells W, Lin P, Agrawal A, Edenberg HJ, Tischfield JA, Schuckit MA, Bierut LJ, Goate A, Rice JP (2013) Dosage transmission disequilibrium test (dTDT) for linkage and association detection. PLOS ONE, 8(5), e63526. PMID: 23691058; PMCID: PMC3653954; DOI: 10.1371/journal.pone.0063526.


2012 [26 Articles]

  1. Agrawal A, Bierut LJ (2012) Identifying genetic variation for alcohol dependence. Alcohol Research: Current Reviews, 34(3), 274-281. PMID: 23134043; PMCID: PMC3662475; LINK.

  2. Agrawal A, Freedman ND, Cheng YC, Lin P, Shaffer JR, Sun Q, Taylor K, Yaspan B, Cole JW, Cornelis MC, DeSensi RS, Fitzpatrick A, Heiss G, Kang JH, O’Connell J, Bennett S, Bookman E, Bucholz KK, Caporaso N, Crout R, Dick DM, Edenberg HJ, Goate A, Hesselbrock V, Kittner S, Kramer J, Nurnberger JI, Jr., Qi L, Rice JP, Schuckit M, van Dam RM, Boerwinkle E, Hu F, Levy S, Marazita M, Mitchell BD, Pasquale LR, Bierut LJ, Geneva Consortium (2012) Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. American Journal of Clinical Nutrition, 95(3), 539-547. PMID: 22301922; PMCID: PMC3278237; DOI: 10.3945/ajcn.111.015545.

  3. Bierut LJ, Goate AM, Breslau N, Johnson EO, Bertelsen S, Fox L, Agrawal A, Bucholz KK, Grucza R, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Porjesz B, Saccone NL, Schuckit M, Tischfield J, Wang JC, Foroud T, Rice JP, Edenberg HJ (2012) ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. Molecular Psychiatry, 17(4), 445-450. PMID: 21968928; PMCID: PMC3252425; DOI: 10.1038/mp.2011.124.

  4. Chen LS, Baker TB, Piper ME, Breslau N, Cannon DS, Doheny KF, Gogarten SM, Johnson EO, Saccone NL, Wang JC, Weiss RB, Goate AM, Bierut LJ (2012) Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success. American Journal of Psychiatry, 169(7), 735-742. PMID: 22648373; PMCID: PMC3433845; DOI: 10.1176/appi.ajp.2012.11101545.

  5. Chen LS, Saccone NL, Culverhouse RC, Bracci PM, Chen CH, Dueker N, Han Y, Huang H, Jin G, Kohno T, Ma JZ, Przybeck TR, Sanders AR, Smith JA, Sung YJ, Wenzlaff AS, Wu C, Yoon D, Chen YT, Cheng YC, Cho YS, David SP, Duan J, Eaton CB, Furberg H, Goate AM, Gu D, Hansen HM, Hartz S, Hu Z, Kim YJ, Kittner SJ, Levinson DF, Mosley TH, Payne TJ, Rao DC, Rice JP, Rice TK, Schwantes-An TH, Shete SS, Shi J, Spitz MR, Sun YV, Tsai FJ, Wang JC, Wrensch MR, Xian H, Gejman PV, He J, Hunt SC, Kardia SL, Li MD, Lin D, Mitchell BD, Park T, Schwartz AG, Shen H, Wiencke JK, Wu JY, Yokota J, Amos CI, Bierut LJ (2012) Smoking and genetic risk variation across populations of European, Asian, and African American ancestry–a meta-analysis of chromosome 15q25. Genetic Epidemiology, 36(4), 340-351. PMID: 22539395; PMCID: PMC3387741; DOI: 10.1002/gepi.21627.

  6. de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Sullivan P, Realo A, Allik J, Heath AC, Pergadia ML, Agrawal A, Lin P, Grucza R, Nutile T, Ciullo M, Rujescu D, Giegling I, Konte B, Widen E, Cousminer DL, Eriksson JG, Palotie A, Peltonen L, Luciano M, Tenesa A, Davies G, Lopez LM, Hansell NK, Medland SE, Ferrucci L, Schlessinger D, Montgomery GW, Wright MJ, Aulchenko YS, Janssens AC, Oostra BA, Metspalu A, Abecasis GR, Deary IJ, Raikkonen K, Bierut LJ, Martin NG, van Duijn CM, Boomsma DI (2012) Meta-analysis of genome-wide association studies for personality. Molecular Psychiatry, 17(3), 337-349. PMID: 21173776; PMCID: PMC3785122; DOI: 10.1038/mp.2010.128.

  7. Derringer J, Krueger RF, Dick DM, Aliev F, Grucza RA, Saccone S, Agrawal A, Edenberg HJ, Goate AM, Hesselbrock VM, Kramer JR, Lin P, Neuman RJ, Nurnberger JI, Jr., Rice JP, Tischfield JA, Bierut LJ (2012) The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach. Behavior Genetics, 42(4), 626-635. PMID: 22358648; PMCID: PMC3416038; DOI: 10.1007/s10519-012-9531-4.

  8. Edenberg HJ (2012) Genes contributing to the development of alcoholism: an overview. Alcohol Research: Current Reviews, 34(3), 336-338. PMID: 23134049; PMCID: PMC3711246; LINK.

  9. Edwards AC, Aliev F, Bierut LJ, Bucholz KK, Edenberg H, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Jr., Schuckit MA, Porjesz B, Dick DM (2012) Genome-wide association study of comorbid depressive syndrome and alcohol dependence. Psychiatric Genetics, 22(1), 31-41. PMID: 22064162; PMCID: PMC3241912; DOI: 10.1097/YPG.0b013e32834acd07.

  10. Harari O, Wang JC, Bucholz K, Edenberg HJ, Heath A, Martin NG, Pergadia ML, Montgomery G, Schrage A, Bierut LJ, Madden PF, Goate AM (2012) Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways. PLOS ONE, 7(12), e50913. PMID: 23227220; PMCID: PMC3515482; DOI: 10.1371/journal.pone.0050913.

  11. Hartz SM, Short SE, Saccone NL, Culverhouse R, Chen L, Schwantes-An TH, Coon H, Han Y, Stephens SH, Sun J, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Geller F, Gubjartsson D, Hansel NN, Jiang C, Keskitalo-Vuokko K, Liu Z, Lyytikainen LP, Michel M, Rawal R, Rosenberger A, Scheet P, Shaffer JR, Teumer A, Thompson JR, Vink JM, Vogelzangs N, Wenzlaff AS, Wheeler W, Xiao X, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty T, Bennett S, Bergen AW, Boyd HA, Broms U, Campbell H, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick DM, Foroud T, Furberg H, Giegling I, Gu F, Hall AS, Hallfors J, Han S, Hartmann AM, Hayward C, Heikkila K, Hewitt JK, Hottenga JJ, Jensen MK, Jousilahti P, Kaakinen M, Kittner SJ, Konte B, Korhonen T, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Muley T, Murray T, Nauck M, North K, Pergadia M, Polasek O, Ramos EM, Ripatti S, Risch A, Ruczinski I, Rudan I, Salomaa V, Schlessinger D, Styrkarsdottir U, Terracciano A, Uda M, Willemsen G, Wu X, Abecasis G, Barnes K, Bickeboller H, Boerwinkle E, Boomsma DI, Caporaso N, Duan J, Edenberg HJ, Francks C, Gejman PV, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Viikari J, Kahonen M, Kendler KS, Lehtimaki T, Levinson DF, Marazita ML, Marchini J, Melbye M, Mitchell BD, Murray JC, Nothen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Sanders AR, Schwartz AG, Shete S, Shi J, Spitz M, Stefansson K, Swan GE, Thorgeirsson T, Volzke H, Wei Q, Wichmann HE, Amos CI, Breslau N, Cannon DS, Ehringer M, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Stitzel JA, Weiss RB, Kraft P, Bierut LJ (2012) Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Archives of General Psychiatry, 69(8), 854-860. PMID: 22868939; PMCID: PMC3482121; DOI: 10.1001/archgenpsychiatry.2012.124.

  12. Hurley TD, Edenberg HJ (2012) Genes encoding enzymes involved in ethanol metabolism. Alcohol Research: Current Reviews, 34(3), 339-344. PMID: 23134050; PMCID: PMC3756590; LINK.

  13. Kamarajan C, Rangaswamy M, Manz N, Chorlian DB, Pandey AK, Roopesh BN, Porjesz B (2012) Topography, power, and current source density of theta oscillations during reward processing as markers for alcohol dependence. Human Brain Mapping, 33(5), 1019-1039. PMID: 21520344; PMCID: PMC3763910; DOI: 10.1002/hbm.21267.

  14. Kang SJ, Rangaswamy M, Manz N, Wang JC, Wetherill L, Hinrichs T, Almasy L, Brooks A, Chorlian DB, Dick D, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Jr., Rice J, Schuckit M, Tischfield J, Bierut LJ, Edenberg HJ, Goate A, Foroud T, Porjesz B (2012) Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6. Genes, Brain and Behavior, 11(6), 712-719. PMID: 22554406; PMCID: PMC3666338; DOI: 10.1111/j.1601-183X.2012.00803.x.

  15. Kapoor M, Wang JC, Bertelsen S, Bucholz K, Budde JP, Hinrichs A, Agrawal A, Brooks A, Chorlian D, Dick D, Hesselbrock V, Foroud T, Kramer J, Kuperman S, Manz N, Nurnberger J, Jr., Porjesz B, Rice J, Tischfield J, Xuei X, Schuckit M, Edenberg HJ, Bierut LJ, Goate AM (2012) Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking. PLOS ONE, 7(3), e33513. PMID: 22438940; PMCID: PMC3306405; DOI: 10.1371/journal.pone.0033513.

  16. Laurie CC, Laurie CA, Rice K, Doheny KF, Zelnick LR, McHugh CP, Ling H, Hetrick KN, Pugh EW, Amos C, Wei Q, Wang LE, Lee JE, Barnes KC, Hansel NN, Mathias R, Daley D, Beaty TH, Scott AF, Ruczinski I, Scharpf RB, Bierut LJ, Hartz SM, Landi MT, Freedman ND, Goldin LR, Ginsburg D, Li J, Desch KC, Strom SS, Blot WJ, Signorello LB, Ingles SA, Chanock SJ, Berndt SI, Le Marchand L, Henderson BE, Monroe KR, Heit JA, de Andrade M, Armasu SM, Regnier C, Lowe WL, Hayes MG, Marazita ML, Feingold E, Murray JC, Melbye M, Feenstra B, Kang JH, Wiggs JL, Jarvik GP, McDavid AN, Seshan VE, Mirel DB, Crenshaw A, Sharopova N, Wise A, Shen J, Crosslin DR, Levine DM, Zheng X, Udren JI, Bennett S, Nelson SC, Gogarten SM, Conomos MP, Heagerty P, Manolio T, Pasquale LR, Haiman CA, Caporaso N, Weir BS (2012) Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nature Genetics, 44(6), 642-650. PMID: 22561516; PMCID: PMC3366033; DOI: 10.1038/ng.2271.

  17. Lin P, Hartz SM, Wang JC, Agrawal A, Zhang TX, McKenna N, Bucholz K, Brooks AI, Tischfield JA, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Schuckit MA, Goate AM, Bierut LJ, Rice JP, COGA Collaborators, COGEND Collaborators, GENEVA (2012) Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. Alcoholism: Clinical and Experimental Research, 36(9), 1512-1518. PMID: 22702843; PMCID: PMC3436997; DOI: 10.1111/j.1530-0277.2012.01758.x.

  18. Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, Sanna S, Terracciano A, Madden PA, Penninx B, Spinhoven P, Hartman CA, Oostra BA, Janssens AC, Eriksson JG, Starr JM, Cannas A, Ferrucci L, Metspalu A, Wright MJ, Heath AC, van Duijn CM, Bierut LJ, Raikkonen K, Martin NG, Ciullo M, Rujescu D, Boomsma DI, Deary IJ (2012) Longevity candidate genes and their association with personality traits in the elderly. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 159b(2), 192-200. PMID: 22213687; PMCID: PMC3583011; DOI: 10.1002/ajmg.b.32013.

  19. Olfson E, Bierut LJ (2012) Convergence of genome-wide association and candidate gene studies for alcoholism. Alcoholism: Clinical and Experimental Research, 36(12), 2086-2094. PMID: 22978509; PMCID: PMC3521088; DOI: 10.1111/j.1530-0277.2012.01843.x.

  20. Pandey AK, Kamarajan C, Rangaswamy M, Porjesz B (2012) Event-Related Oscillations in Alcoholism Research: A Review. Journal of Addiction Research & Therapy, Suppl 7(1), 1-13. PMID: 24273686; PMCID: PMC3835599; DOI: 10.4172/2155-6105.S7-001.

  21. Pandey AK, Kamarajan C, Tang Y, Chorlian DB, Roopesh BN, Manz N, Stimus A, Rangaswamy M, Porjesz B (2012) Neurocognitive deficits in male alcoholics: an ERP/sLORETA analysis of the N2 component in an equal probability Go/NoGo task. Biological Psychology, 89(1), 170-182. PMID: 22024409; PMCID: PMC3245806; DOI: 10.1016/j.biopsycho.2011.10.009.

  22. Rice JP, Hartz SM, Agrawal A, Almasy L, Bennett S, Breslau N, Bucholz KK, Doheny KF, Edenberg HJ, Goate AM, Hesselbrock V, Howells WB, Johnson EO, Kramer J, Krueger RF, Kuperman S, Laurie C, Manolio TA, Neuman RJ, Nurnberger JI, Porjesz B, Pugh E, Ramos EM, Saccone N, Saccone S, Schuckit M, Bierut LJ, Consortium G (2012) CHRNB3 is more strongly associated with Fagerstrom test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. Addiction, 107(11), 2019-2028. PMID: 22524403; PMCID: PMC3427406; DOI: 10.1111/j.1360-0443.2012.03922.x.

  23. Schuckit MA, Smith TL, Trim RS, Kuperman S, Kramer J, Hesselbrock V, Bucholz KK, Nurnberger JI, Jr., Hesselbrock M, Saunders G (2012) Sex differences in how a low sensitivity to alcohol relates to later heavy drinking. Drug and Alcohol Review, 31(7), 871-880. PMID: 22708705; PMCID: PMC3459074; DOI: 10.1111/j.1465-3362.2012.00469.x.

  24. Spitz MR, Amos CI, Bierut LJ, Caporaso NE (2012) Cotinine conundrum–a step forward but questions remain. Journal of the National Cancer Institute, 104(10), 720-722. PMID: 22534783; PMCID: PMC3352835; DOI: 10.1093/jnci/djs211.

  25. Wang JC, Kapoor M, Goate AM (2012) The genetics of substance dependence. Annu Rev Genomics Hum Genet, 13, 241-261. PMID: 22703173; PMCID: PMC3474605; DOI: 10.1146/annurev-genom-090711-163844.

  26. Zhao Z, Guo AY, van den Oord EJ, Aliev F, Jia P, Edenberg HJ, Riley BP, Dick DM, Bettinger JC, Davies AG, Grotewiel MS, Schuckit MA, Agrawal A, Kramer J, Nurnberger JI, Jr., Kendler KS, Webb BT, Miles MF (2012) Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study. BMC Genomics, 13 Suppl 8(Suppl 8), S16. PMID: 23282140; PMCID: PMC3535715; DOI: 10.1186/1471-2164-13-s8-s16.


2011 [20 Articles]

  1. Agrawal A, Freedman ND, Bierut LJ (2011) Genome-wide association studies of alcohol intake–a promising cocktail? American Journal of Clinical Nutrition, 93(4), 681-683. PMID: 21367945; PMCID: PMC3057543; DOI: 10.3945/ajcn.111.012641.

  2. Agrawal A, Lynskey MT, Hinrichs A, Grucza R, Saccone SF, Krueger R, Neuman R, Howells W, Fisher S, Fox L, Cloninger R, Dick DM, Doheny KF, Edenberg HJ, Goate AM, Hesselbrock V, Johnson E, Kramer J, Kuperman S, Nurnberger JI, Jr., Pugh E, Schuckit M, Tischfield J, GENEVA Consortium, Rice JP, Bucholz KK, Bierut LJ (2011) A genome-wide association study of DSM-IV cannabis dependence. Addiction Biology, 16(3), 514-518. PMID: 21668797; PMCID: PMC3117436; DOI: 10.1111/j.1369-1600.2010.00255.x.

  3. Bennett SN, Caporaso N, Fitzpatrick AL, Agrawal A, Barnes K, Boyd HA, Cornelis MC, Hansel NN, Heiss G, Heit JA, Kang JH, Kittner SJ, Kraft P, Lowe W, Marazita ML, Monroe KR, Pasquale LR, Ramos EM, van Dam RM, Udren J, Williams K, GENEVA Consortium (2011) Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. Genetic Epidemiology, 35(3), 159-173. PMID: 21284036; PMCID: PMC3055921; DOI: 10.1002/gepi.20564.

  4. Bierut LJ (2011) Genetic vulnerability and susceptibility to substance dependence. Neuron, 69(4), 618-627. PMID: 21338875; PMCID: PMC3095110; DOI: 10.1016/j.neuron.2011.02.015.

  5. Derringer J, Krueger RF, Manz N, Porjesz B, Almasy L, Bookman E, Edenberg HJ, Kramer JR, Tischfield JA, Bierut LJ (2011) Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power. Psychiatric Genetics,� PMID: 21317682; DOI: 10.1097/YPG.0b013e32834371fd.

  6. Dick DM (2011) Gene-environment interaction in psychological traits and disorders. Annual Review of Clinical Psychology, 7, 383-409. PMID: 21219196; PMCID: PMC3647367; DOI: 10.1146/annurev-clinpsy-032210-104518.

  7. Dick DM, Aliev F, Krueger RF, Edwards A, Agrawal A, Lynskey M, Lin P, Schuckit M, Hesselbrock V, Nurnberger J, Jr., Almasy L, Porjesz B, Edenberg HJ, Bucholz K, Kramer J, Kuperman S, Bierut L (2011) Genome-wide association study of conduct disorder symptomatology. Molecular Psychiatry, 16(8), 800-808. PMID: 20585324; PMCID: PMC3580835; DOI: 10.1038/mp.2010.73.

  8. Dick DM, Meyers JL, Latendresse SJ, Creemers HE, Lansford JE, Pettit GS, Bates JE, Dodge KA, Budde J, Goate A, Buitelaar JK, Ormel J, Verhulst FC, Huizink AC (2011) CHRM2, parental monitoring, and adolescent externalizing behavior: evidence for gene-environment interaction. Psychological Science, 22(4), 481-489. PMID: 21441226; PMCID: PMC3391964; DOI: 10.1177/0956797611403318.

  9. Edenberg HJ (2011) Common and rare variants in alcohol dependence. Biological Psychiatry, 70(6), 498-499. PMID: 21864733; DOI: 10.1016/j.biopsych.2011.07.007.

  10. Hartz SM, Johnson EO, Saccone NL, Hatsukami D, Breslau N, Bierut LJ (2011) Inclusion of African Americans in genetic studies: what is the barrier? American Journal of Epidemiology, 174(3), 336-344. PMID: 21633120; PMCID: PMC3202157; DOI: 10.1093/aje/kwr084.

  11. Hinrichs AL, Culverhouse RC, Suarez BK (2011) Linkage analysis merging replicate phenotypes: an application to three quantitative phenotypes in two African samples. BMC Proceedings, 5 Suppl 9(Suppl 9), S81. PMID: 22373343; PMCID: PMC3287922; DOI: 10.1186/1753-6561-5-s9-s81.

  12. Johnson C, Drgon T, Walther D, Uhl GR (2011) Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence. PLOS ONE, 6(7), e19210. PMID: 21818250; PMCID: PMC3144872; DOI: 10.1371/journal.pone.0019210.

  13. Latendresse SJ, Bates JE, Goodnight JA, Lansford JE, Budde JP, Goate A, Dodge KA, Pettit GS, Dick DM (2011) Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. Child Development, 82(6), 1797-1814. PMID: 21883161; PMCID: PMC3218245; DOI: 10.1111/j.1467-8624.2011.01640.x.

  14. Lin P, Hartz SM, Wang JC, Krueger RF, Foroud TM, Edenberg HJ, Nurnberger JI, Jr., Brooks AI, Tischfield JA, Almasy L, Webb BT, Hesselbrock VM, Porjesz B, Goate AM, Bierut LJ, Rice JP (2011) Copy number variation accuracy in genome-wide association studies. Human Heredity, 71(3), 141-147. PMID: 21778733; PMCID: PMC3153341; DOI: 10.1159/000324683.

  15. Maher BS, Vladimirov VI, Latendresse SJ, Thiselton DL, McNamee R, Kang M, Bigdeli TB, Chen X, Riley BP, Hettema JM, Chilcoat H, Heidbreder C, Muglia P, Murrelle EL, Dick DM, Aliev F, Agrawal A, Edenberg HJ, Kramer J, Nurnberger J, Tischfield JA, Devlin B, Ferrell RE, Kirillova GP, Tarter RE, Kendler KS, Vanyukov MM (2011) The AVPR1A gene and substance use disorders: association, replication, and functional evidence. Biological Psychiatry, 70(6), 519-527. PMID: 21514569; PMCID: PMC4083653; DOI: 10.1016/j.biopsych.2011.02.023.

  16. McCutcheon VV, Agrawal A, Heath AC, Edenberg HJ, Hesselbrock VM, Schuckit MA, Kramer JR, Bucholz KK (2011) Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol. Alcoholism: Clinical and Experimental Research, 35(11), 1985-1993. PMID: 21631541; PMCID: PMC3166544; DOI: 10.1111/j.1530-0277.2011.01550.x.

  17. Middeldorp CM, de Moor MH, McGrath LM, Gordon SD, Blackwood DH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Nyholt DR, Tanaka T, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Ripke S, Sullivan PF, Realo A, Allik J, Heath AC, Pergadia ML, Agrawal A, Lin P, Grucza RA, Widen E, Cousminer DL, Eriksson JG, Palotie A, Barnett JH, Lee PH, Luciano M, Tenesa A, Davies G, Lopez LM, Hansell NK, Medland SE, Ferrucci L, Schlessinger D, Montgomery GW, Wright MJ, Aulchenko YS, Janssens AC, Oostra BA, Metspalu A, Abecasis GR, Deary IJ, Raikkonen K, Bierut LJ, Martin NG, Wray NR, van Duijn CM, Smoller JW, Penninx BW, Boomsma DI (2011) The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data. Translational Psychiatry, 1(10), e50. PMID: 22833196; PMCID: PMC3309491; DOI: 10.1038/tp.2011.45.

  18. Schuckit MA, Smith TL, Trim RS, Allen RC, Fukukura T, Knight EE, Cesario EM, Kreikebaum SA (2011) A prospective evaluation of how a low level of response to alcohol predicts later heavy drinking and alcohol problems. American Journal of Drug and Alcohol Abuse, 37(6), 479-486. PMID: 21797810; DOI: 10.3109/00952990.2011.598590.

  19. Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivieres S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proenca C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Fernandez-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Nunez A, Nyholt DR, Onland-Moret CN, Oostra BA, O’Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tonjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P (2011) Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America, 108(17), 7119-7124. PMID: 21471458; PMCID: PMC3084048; DOI: 10.1073/pnas.1017288108.

  20. Zlojutro M, Manz N, Rangaswamy M, Xuei X, Flury-Wetherill L, Koller D, Bierut LJ, Goate A, Hesselbrock V, Kuperman S, Nurnberger J, Jr., Rice JP, Schuckit MA, Foroud T, Edenberg HJ, Porjesz B, Almasy L (2011) Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 156B(1), 44-58. PMID: 21184583; PMCID: PMC3139811; DOI: 10.1002/ajmg.b.31136.


2010 [27 Articles]

  1. Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bolte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Carson AR, Casallo G, Casey J, Chu SH, Cochrane L, Corsello C, Crawford EL, Crossett A, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Melhem NM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Piven J, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Wing K, Wittemeyer K, Wood S, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Gallagher L, Geschwind DH, Gill M, Haines JL, Miller J, Monaco AP, Nurnberger JI, Jr., Paterson AD, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Devlin B, Ennis S, Hallmayer J (2010) A genome-wide scan for common alleles affecting risk for autism. Human Molecular Genetics, 19(20), 4072-4082. PMID: 20663923; PMCID: PMC2947401; DOI: 10.1093/hmg/ddq307.

  2. Bauer L, Dick D, Bierut L, Bucholz K, Edenberg H, Kuperman S, Kramer J, Nurnberger J, O’Connor S, Rice J, Rohrbaugh J, Schuckit M, Tischfield J, Porjesz B, Hesselbrock V (2010) Obesity, smoking, and frontal brain dysfunction. American Journal on Addictions, 19(5), 391-400. PMID: 20716301; PMCID: PMC2924769; DOI: 10.1111/j.1521-0391.2010.00069.x.

  3. Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nothen MM, Nurnberger JI, Jr., Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP, Gene EASC (2010) A genome-wide association study of alcohol dependence. Proceedings of the National Academy of Sciences of the United States of America, 107(11), 5082-5087. PMID: 20202923; PMCID: PMC2841942; DOI: 10.1073/pnas.0911109107.

  4. Cavazos-Rehg PA, Spitznagel EL, Bucholz KK, Nurnberger J, Jr., Edenberg HJ, Kramer JR, Kuperman S, Hesselbrock V, Bierut LJ (2010) Predictors of sexual debut at age 16 or younger. Archives of Sexual Behavior, 39(3), 664-673. PMID: 18846417; PMCID: PMC2855761; DOI: 10.1007/s10508-008-9397-y.

  5. Chen AC, Manz N, Tang Y, Rangaswamy M, Almasy L, Kuperman S, Nurnberger J, Jr., O’Connor SJ, Edenberg HJ, Schuckit MA, Tischfield J, Foroud T, Bierut LJ, Rohrbaugh J, Rice JP, Goate A, Hesselbrock V, Porjesz B (2010) Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. Alcoholism: Clinical and Experimental Research, 34(6), 988-996. PMID: 20374216; PMCID: PMC3248053; DOI: 10.1111/j.1530-0277.2010.01173.x.

  6. Cornelis MC, Agrawal A, Cole JW, Hansel NN, Barnes KC, Beaty TH, Bennett SN, Bierut LJ, Boerwinkle E, Doheny KF, Feenstra B, Feingold E, Fornage M, Haiman CA, Harris EL, Hayes MG, Heit JA, Hu FB, Kang JH, Laurie CC, Ling H, Manolio TA, Marazita ML, Mathias RA, Mirel DB, Paschall J, Pasquale LR, Pugh EW, Rice JP, Udren J, van Dam RM, Wang X, Wiggs JL, Williams K, Yu K (2010) The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genetic Epidemiology, 34(4), 364-372. PMID: 20091798; PMCID: PMC2860056; DOI: 10.1002/gepi.20492.

  7. Derringer J, Krueger RF, Dick DM, Saccone S, Grucza RA, Agrawal A, Lin P, Almasy L, Edenberg HJ, Foroud T, Nurnberger JI, Jr., Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, Schuckit MA, Bierut LJ, Gene Environment Association Studies C (2010) Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychological Science, 21(9), 1282-1290. PMID: 20732903; PMCID: PMC3031097; DOI: 10.1177/0956797610380699.

  8. Dick DM, Meyers J, Aliev F, Nurnberger J, Jr., Kramer J, Kuperman S, Porjesz B, Tischfield J, Edenberg HJ, Foroud T, Schuckit M, Goate A, Hesselbrock V, Bierut L (2010) Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 153B(6), 1179-1188. PMID: 20468071; PMCID: PMC3597340; DOI: 10.1002/ajmg.b.31089.

  9. Dick DM, Smith G, Olausson P, Mitchell SH, Leeman RF, O’Malley SS, Sher K (2010) Understanding the construct of impulsivity and its relationship to alcohol use disorders. Addiction Biology, 15(2), 217-226. PMID: 20148781; PMCID: PMC2895996; DOI: 10.1111/j.1369-1600.2009.00190.x.

  10. Edenberg HJ, Koller DL, Xuei X, Wetherill L, McClintick JN, Almasy L, Bierut LJ, Bucholz KK, Goate A, Aliev F, Dick D, Hesselbrock V, Hinrichs A, Kramer J, Kuperman S, Nurnberger JI, Jr., Rice JP, Schuckit MA, Taylor R, Todd Webb B, Tischfield JA, Porjesz B, Foroud T (2010) Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcoholism: Clinical and Experimental Research, 34(5), 840-852. PMID: 20201924; PMCID: PMC2884073; DOI: 10.1111/j.1530-0277.2010.01156.x.

  11. Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington NM, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, Barroso I, Berenson GS, Bergmann S, Blackburn H, Boerwinkle E, Buring JE, Busonero F, Campbell H, Chanock SJ, Chen W, Cornelis MC, Couper D, Coviello AD, d’Adamo P, de Faire U, de Geus EJ, Deloukas P, Doring A, Smith GD, Easton DF, Eiriksdottir G, Emilsson V, Eriksson J, Ferrucci L, Folsom AR, Foroud T, Garcia M, Gasparini P, Geller F, Gieger C, Consortium G, Gudnason V, Hall P, Hankinson SE, Ferreli L, Heath AC, Hernandez DG, Hofman A, Hu FB, Illig T, Jarvelin MR, Johnson AD, Karasik D, Khaw KT, Kiel DP, Kilpelainen TO, Kolcic I, Kraft P, Launer LJ, Laven JS, Li S, Liu J, Levy D, Martin NG, McArdle WL, Melbye M, Mooser V, Murray JC, Murray SS, Nalls MA, Navarro P, Nelis M, Ness AR, Northstone K, Oostra BA, Peacock M, Palmer LJ, Palotie A, Pare G, Parker AN, Pedersen NL, Peltonen L, Pennell CE, Pharoah P, Polasek O, Plump AS, Pouta A, Porcu E, Rafnar T, Rice JP, Ring SM, Rivadeneira F, Rudan I, Sala C, Salomaa V, Sanna S, Schlessinger D, Schork NJ, Scuteri A, Segre AV, Shuldiner AR, Soranzo N, Sovio U, Srinivasan SR, Strachan DP, Tammesoo ML, Tikkanen E, Toniolo D, Tsui K, Tryggvadottir L, Tyrer J, Uda M, van Dam RM, van Meurs JB, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Weedon MN, Wichmann HE, Willemsen G, Wilson JF, Wright AF, Young L, Zhai G, Zhuang WV, Bierut LJ, Boomsma DI, Boyd HA, Crisponi L, Demerath EW, van Duijn CM, Econs MJ, Harris TB, Hunter DJ, Loos RJ, Metspalu A, Montgomery GW, Ridker PM, Spector TD, Streeten EA, Stefansson K, Thorsteinsdottir U, Uitterlinden AG, Widen E, Murabito JM, Ong KK, Murray A (2010) Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics, 42(12), 1077-1085. PMID: 21102462; PMCID: PMC3140055; DOI: 10.1038/ng.714.

  12. Foroud T, Edenberg HJ, Crabbe JC (2010) Genetic research: who is at risk for alcoholism. Alcohol Research and Health, 33(1-2), 64-75. PMID: 23579937; PMCID: PMC3887503; LINK.

  13. Grucza RA, Krueger RF, Racette SB, Norberg KE, Hipp PR, Bierut LJ (2010) The emerging link between alcoholism risk and obesity in the United States. Archives of General Psychiatry, 67(12), 1301-1308. PMID: 21135330; PMCID: PMC3110764; DOI: 10.1001/archgenpsychiatry.2010.155.

  14. Hartz SM, Bierut LJ (2010) Genetics of addictions. Psychiatric Clinics of North America, 33(1), 107-124. PMID: 20159342; PMCID: PMC3047504; DOI: 10.1016/j.psc.2009.10.003.

  15. Jonson-Reid M, Presnall N, Drake B, Fox L, Bierut L, Reich W, Kane P, Todd RD, Constantino JN (2010) Effects of child maltreatment and inherited liability on antisocial development: an official records study. Journal of the American Academy of Child and Adolescent Psychiatry, 49(4), 321-332; quiz 431. PMID: 20410725; PMCID: PMC2878182; DOI: 10.1016/j.jaac.2009.11.015.

  16. Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J, Jr., Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP (2010) A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. Human Molecular Genetics, 19(12), 2497-2506. PMID: 20332099; PMCID: PMC2876884; DOI: 10.1093/hmg/ddq112.

  17. Kamarajan C, Rangaswamy M, Tang Y, Chorlian DB, Pandey AK, Roopesh BN, Manz N, Saunders R, Stimus AT, Porjesz B (2010) Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. Journal of Psychiatric Research, 44(9), 576-590. PMID: 20035952; PMCID: PMC2878886; DOI: 10.1016/j.jpsychires.2009.11.019.

  18. Kramer JR, Chan G, Hesselbrock VM, Kuperman S, Bucholz KK, Edenberg HJ, Schuckit MA, Nurnberger JI, Foroud T, Dick DM, Bierut LJ, Porjesz B (2010) A principal components analysis of the abbreviated Desires for Alcohol Questionnaire (DAQ). Journal of Studies on Alcohol and Drugs, 71(1), 150-155. PMID: 20105425; PMCID: PMC2815057; DOI: 10.15288/jsad.2010.71.150.

  19. Laurie CC, Doheny KF, Mirel DB, Pugh EW, Bierut LJ, Bhangale T, Boehm F, Caporaso NE, Cornelis MC, Edenberg HJ, Gabriel SB, Harris EL, Hu FB, Jacobs KB, Kraft P, Landi MT, Lumley T, Manolio TA, McHugh C, Painter I, Paschall J, Rice JP, Rice KM, Zheng X, Weir BS (2010) Quality control and quality assurance in genotypic data for genome-wide association studies. Genetic Epidemiology, 34(6), 591-602. PMID: 20718045; PMCID: PMC3061487; DOI: 10.1002/gepi.20516.

  20. Lin P, Hartz SM, Zhang Z, Saccone SF, Wang J, Tischfield JA, Edenberg HJ, Kramer JR, A MG, Bierut LJ, Rice JP (2010) A new statistic to evaluate imputation reliability. PLOS ONE, 5(3), e9697. PMID: 20300623; PMCID: PMC2837741; DOI: 10.1371/journal.pone.0009697.

  21. Meyers JL, Dick DM (2010) Genetic and environmental risk factors for adolescent-onset substance use disorders. Child and Adolescent Psychiatric Clinics of North America, 19(3), 465-477. PMID: 20682215; PMCID: PMC3661209; DOI: 10.1016/j.chc.2010.03.013.

  22. Noor A, Whibley A, Marshall CR, Gianakopoulos PJ, Piton A, Carson AR, Orlic-Milacic M, Lionel AC, Sato D, Pinto D, Drmic I, Noakes C, Senman L, Zhang X, Mo R, Gauthier J, Crosbie J, Pagnamenta AT, Munson J, Estes AM, Fiebig A, Franke A, Schreiber S, Stewart AF, Roberts R, McPherson R, Guter SJ, Cook EH, Jr., Dawson G, Schellenberg GD, Battaglia A, Maestrini E, Jeng L, Hutchison T, Rajcan-Separovic E, Chudley AE, Lewis SM, Liu X, Holden JJ, Fernandez B, Zwaigenbaum L, Bryson SE, Roberts W, Szatmari P, Gallagher L, Stratton MR, Gecz J, Brady AF, Schwartz CE, Schachar RJ, Monaco AP, Rouleau GA, Hui CC, Lucy Raymond F, Scherer SW, Vincent JB (2010) Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability. Science Translational Medicine, 2(49), 49ra68. PMID: 20844286; PMCID: PMC2987731; DOI: 10.1126/scitranslmed.3001267.

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  24. Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliovaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nothen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ (2010) Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genetics, 6(8), e1001053. PMID: 20700436; PMCID: PMC2916847; DOI: 10.1371/journal.pgen.1001053.

  25. Saccone SF, Bolze R, Thomas P, Quan J, Mehta G, Deelman E, Tischfield JA, Rice JP (2010) SPOT: a web-based tool for using biological databases to prioritize SNPs after a genome-wide association study. Nucleic Acids Research, 38(Web Server issue), W201-209. PMID: 20529875; PMCID: PMC2896195; DOI: 10.1093/nar/gkq513.

  26. Thornton T, McPeek MS (2010) ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. American Journal of Human Genetics, 86(2), 172-184. PMID: 20137780; PMCID: PMC2820184; DOI: 10.1016/j.ajhg.2010.01.001.

  27. Xuei X, Flury-Wetherill L, Dick D, Goate A, Tischfield J, Nurnberger J, Jr., Schuckit M, Kramer J, Kuperman S, Hesselbrock V, Porjesz B, Foroud T, Edenberg HJ (2010) GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 153B(2), 418-427. PMID: 19536785; PMCID: PMC2829340; DOI: 10.1002/ajmg.b.30995.


2009 [17 Articles]

  1. Agrawal A, Wetherill L, Dick DM, Xuei X, Hinrichs A, Hesselbrock V, Kramer J, Nurnberger JI, Jr., Schuckit M, Bierut LJ, Edenberg HJ, Foroud T (2009) Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 150b(5), 736-740. PMID: 19016476; PMCID: PMC2703788; DOI: 10.1002/ajmg.b.30881.

  2. Cavazos-Rehg PA, Spitznagel EL, Schootman M, Strickland JR, Afful SE, Cottler LB, Bierut LJ (2009) Risky sexual behaviors and sexually transmitted diseases: a comparison study of cocaine-dependent individuals in treatment versus a community-matched sample. AIDS Patient Care STDS, 23(9), 727-734. PMID: 19645618; PMCID: PMC2804246; DOI: 10.1089/apc.2008.0272.

  3. Chen AC, Tang Y, Rangaswamy M, Wang JC, Almasy L, Foroud T, Edenberg HJ, Hesselbrock V, Nurnberger J, Jr., Kuperman S, O’Connor SJ, Schuckit MA, Bauer LO, Tischfield J, Rice JP, Bierut L, Goate A, Porjesz B (2009) Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 150B(3), 359-368. PMID: 18618593; PMCID: PMC2660384; DOI: 10.1002/ajmg.b.30818.

  4. Chorlian DB, Rangaswamy M, Porjesz B (2009) EEG coherence: topography and frequency structure. Experimental Brain Research, 198(1), 59-83. PMID: 19626316; DOI: 10.1007/s00221-009-1936-9.

  5. Grucza RA, Norberg KE, Bierut LJ (2009) Binge drinking among youths and young adults in the United States: 1979-2006. Journal of the American Academy of Child and Adolescent Psychiatry, 48(7), 692-702. PMID: 19465879; PMCID: PMC2862553; DOI: 10.1097/CHI.0b013e3181a2b32f.

  6. Hurley JH, Ballard CJ, Edenberg HJ (2009) Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes. Alcoholism: Clinical and Experimental Research, 33(6), 1089-1096. PMID: 19382902; PMCID: PMC4136686; DOI: 10.1111/j.1530-0277.2009.00930.x.

  7. Kamarajan C, Porjesz B, Rangaswamy M, Tang Y, Chorlian DB, Padmanabhapillai A, Saunders R, Pandey AK, Roopesh BN, Manz N, Stimus AT, Begleiter H (2009) Brain signatures of monetary loss and gain: outcome-related potentials in a single outcome gambling task. Behavioural Brain Research, 197(1), 62-76. PMID: 18775749; PMCID: PMC2645043; DOI: 10.1016/j.bbr.2008.08.011.

  8. Kramer JR, Chan G, Kuperman S, Bucholz KK, Edenberg HJ, Schuckit MA, Polgreen LA, Kapp ES, Hesselbrock VM, Nurnberger JI, Bierut LJ (2009) A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA). Journal of Studies on Alcohol and Drugs, 70(4), 623-627. PMID: 19515304; PMCID: PMC2696302; DOI: 10.15288/jsad.2009.70.623.

  9. Lester HA, Xiao C, Srinivasan R, Son CD, Miwa J, Pantoja R, Banghart MR, Dougherty DA, Goate AM, Wang JC (2009) Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. The AAPS Journal, 11(1), 167-177. PMID: 19280351; PMCID: PMC2664890; DOI: 10.1208/s12248-009-9090-7.

  10. McCutcheon VV, Heath AC, Edenberg HJ, Grucza RA, Hesselbrock VM, Kramer JR, Bierut LJ, Bucholz KK (2009) Alcohol criteria endorsement and psychiatric and drug use disorders among DUI offenders: greater severity among women and multiple offenders. Addictive Behaviors, 34(5), 432-439. PMID: 19167170; PMCID: PMC2855219; DOI: 10.1016/j.addbeh.2008.12.003.

  11. Norberg KE, Bierut LJ, Grucza RA (2009) Long-term effects of minimum drinking age laws on past-year alcohol and drug use disorders. Alcoholism: Clinical and Experimental Research, 33(12), 2180-2190. PMID: 19775322; PMCID: PMC3018854; DOI: 10.1111/j.1530-0277.2009.01056.x.

  12. Roopesh BN, Rangaswamy M, Kamarajan C, Chorlian DB, Stimus A, Bauer LO, Rohrbaugh J, O’Connor SJ, Kuperman S, Schuckit M, Porjesz B (2009) Priming deficiency in male subjects at risk for alcoholism: the N4 during a lexical decision task. Alcoholism: Clinical and Experimental Research, 33(12), 2027-2036. PMID: 19764939; PMCID: PMC3601897; DOI: 10.1111/j.1530-0277.2009.01042.x.

  13. Schuckit MA (2009) Alcohol-use disorders. Lancet, 373(9662), 492-501. PMID: 19168210; DOI: 10.1016/s0140-6736(09)60009-x.

  14. Schuckit MA, Smith TL, Danko GP, Trim R, Bucholz KK, Edenberg HJ, Hesselbrock V, Kramer JJ, Dick DM (2009) An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring. Journal of Studies on Alcohol and Drugs, 70(3), 436-445. PMID: 19371495; PMCID: PMC2670749; DOI: 10.15288/jsad.2009.70.436.

  15. Schuckit MA, Smith TL, Trim R, Fukukura T, Allen R (2009) The overlap in predicting alcohol outcome for two measures of the level of response to alcohol. Alcoholism: Clinical and Experimental Research, 33(3), 563-569. PMID: 19120060; PMCID: PMC2651993; DOI: 10.1111/j.1530-0277.2008.00870.x.

  16. Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM (2009) Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Human Molecular Genetics, 18(16), 3125-3135. PMID: 19443489; PMCID: PMC2714722; DOI: 10.1093/hmg/ddp231.

  17. Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP, Fox L, Goldstein E, Reyes O, Saccone N, Saccone S, Xuei X, Bucholz K, Kuperman S, Nurnberger J, Jr., Rice JP, Schuckit M, Tischfield J, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate AM (2009) Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Molecular Psychiatry, 14(5), 501-510. PMID: 18414406; PMCID: PMC4381434; DOI: 10.1038/mp.2008.42.


2008 [23 Articles]

  1. Agrawal A, Hinrichs AL, Dunn G, Bertelsen S, Dick DM, Saccone SF, Saccone NL, Grucza RA, Wang JC, Cloninger CR, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Bucholz KK, Kuperman S, Nurnberger JI, Jr., Porjesz B, Schuckit MA, Goate AM, Bierut LJ (2008) Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Drug and Alcohol Dependence, 93(1-2), 12-20. PMID: 17942244; PMCID: PMC2266629; DOI: 10.1016/j.drugalcdep.2007.08.015.

  2. Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X, Saccone NL, Saccone SF, Bertelsen S, Fox L, Horton WJ, Breslau N, Budde J, Cloninger CR, Dick DM, Foroud T, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Kuperman S, Madden PA, Mayo K, Nurnberger J, Jr., Pomerleau O, Porjesz B, Reyes O, Schuckit M, Swan G, Tischfield JA, Edenberg HJ, Rice JP, Goate AM (2008) Variants in nicotinic receptors and risk for nicotine dependence. American Journal of Psychiatry, 165(9), 1163-1171. PMID: 18519524; PMCID: PMC2574742; DOI: 10.1176/appi.ajp.2008.07111711.

  3. Bierut LJ, Strickland JR, Thompson JR, Afful SE, Cottler LB (2008) Drug use and dependence in cocaine dependent subjects, community-based individuals, and their siblings. Drug and Alcohol Dependence, 95(1-2), 14-22. PMID: 18243582; PMCID: PMC2384165; DOI: 10.1016/j.drugalcdep.2007.11.023.

  4. Dick DM, Agrawal A (2008) The genetics of alcohol and other drug dependence. Alcohol Research and Health, 31(2), 111-118. PMID: 23584813; PMCID: PMC3860452; LINK.

  5. Dick DM, Aliev F, Wang JC, Grucza RA, Schuckit M, Kuperman S, Kramer J, Hinrichs A, Bertelsen S, Budde JP, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate A (2008) Using dimensional models of externalizing psychopathology to aid in gene identification. Archives of General Psychiatry, 65(3), 310-318. PMID: 18316677; DOI: 10.1001/archpsyc.65.3.310.

  6. Dick DM, Aliev F, Wang JC, Saccone S, Hinrichs A, Bertelsen S, Budde J, Saccone N, Foroud T, Nurnberger J, Jr., Xuei X, Conneally PM, Schuckit M, Almasy L, Crowe R, Kuperman S, Kramer J, Tischfield JA, Hesselbrock V, Edenberg HJ, Porjesz B, Rice JP, Bierut L, Goate A (2008) A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9. Biological Psychiatry, 63(11), 1047-1053. PMID: 18163977; PMCID: PMC3823371; DOI: 10.1016/j.biopsych.2007.11.005.

  7. Edenberg HJ, Wang J, Tian H, Pochareddy S, Xuei X, Wetherill L, Goate A, Hinrichs T, Kuperman S, Nurnberger JI, Jr., Schuckit M, Tischfield JA, Foroud T (2008) A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence. Human Molecular Genetics, 17(12), 1783-1789. PMID: 18319328; PMCID: PMC2405904; DOI: 10.1093/hmg/ddn068.

  8. Edenberg HJ, Xuei X, Wetherill LF, Bierut L, Bucholz K, Dick DM, Hesselbrock V, Kuperman S, Porjesz B, Schuckit MA, Tischfield JA, Almasy LA, Nurnberger JI, Jr., Foroud T (2008) Association of NFKB1, which encodes a subunit of the transcription factor NF-kappaB, with alcohol dependence. Human Molecular Genetics, 17(7), 963-970. PMID: 18079108; DOI: 10.1093/hmg/ddm368.

  9. Foroud T, Wetherill LF, Kramer J, Tischfield JA, Nurnberger JI, Jr., Schuckit MA, Xuei X, Edenberg HJ (2008) The tachykinin receptor 3 is associated with alcohol and cocaine dependence. Alcoholism: Clinical and Experimental Research, 32(6), 1023-1030. PMID: 18422838; PMCID: PMC2430628; DOI: 10.1111/j.1530-0277.2008.00663.x.

  10. Ghosh S, Bierut LJ, Porjesz B, Edenberg HJ, Dick D, Goate A, Hesselbrock V, Nurnberger J, Jr., Foroud T, Kramer J, Rice J, Begleiter H (2008) A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 147b(7), 1301-1305. PMID: 18454434; PMCID: PMC2879266; DOI: 10.1002/ajmg.b.30735.

  11. Grucza RA, Bucholz KK, Rice JP, Bierut LJ (2008) Secular trends in the lifetime prevalence of alcohol dependence in the United States: a re-evaluation. Alcoholism: Clinical and Experimental Research, 32(5), 763-770. PMID: 18336633; PMCID: PMC2443101; DOI: 10.1111/j.1530-0277.2008.00635.x.

  12. Grucza RA, Norberg K, Bucholz KK, Bierut LJ (2008) Correspondence between secular changes in alcohol dependence and age of drinking onset among women in the United States. Alcoholism: Clinical and Experimental Research, 32(8), 1493-1501. PMID: 18564104; PMCID: PMC2661151; DOI: 10.1111/j.1530-0277.2008.00719.x.

  13. Grucza RA, Wang JC, Stitzel JA, Hinrichs AL, Saccone SF, Saccone NL, Bucholz KK, Cloninger CR, Neuman RJ, Budde JP, Fox L, Bertelsen S, Kramer J, Hesselbrock V, Tischfield J, Nurnberger JI, Jr., Almasy L, Porjesz B, Kuperman S, Schuckit MA, Edenberg HJ, Rice JP, Goate AM, Bierut LJ (2008) A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biological Psychiatry, 64(11), 922-929. PMID: 18519132; PMCID: PMC2582594; DOI: 10.1016/j.biopsych.2008.04.018.

  14. Kramer JR, Chan G, Dick DM, Kuperman S, Bucholz KK, Edenberg HJ, Polgreen LA, Hesselbrock VM, Schuckit MA, Nurnberger JI, Kapp ES, Porjesz B, Bierut LJ (2008) Multiple-domain predictors of problematic alcohol use in young adulthood. Journal of Studies on Alcohol and Drugs, 69(5), 649-659. PMID: 18781239; PMCID: PMC2575389; DOI: 10.15288/jsad.2008.69.649.

  15. Mayfield RD, Harris RA, Schuckit MA (2008) Genetic factors influencing alcohol dependence. British Journal of Pharmacology, 154(2), 275-287. PMID: 18362899; PMCID: PMC2442454; DOI: 10.1038/bjp.2008.88.

  16. Pescosolido BA, Perry BL, Long JS, Martin JK, Nurnberger JI, Jr., Hesselbrock V (2008) Under the influence of genetics: how transdisciplinarity leads us to rethink social pathways to illness. AJS: American Journal of Sociology, 114 Suppl(0), S171-201. PMID: 19569404; PMCID: PMC4443492; DOI: 10.1086/592209.

  17. Rangaswamy M, Porjesz B (2008) From event-related potential to oscillations: genetic diathesis in brain (dys)function and alcohol dependence. Alcohol Research and Health, 31(3), 238-242. PMID: 23584866; PMCID: PMC3860487; LINK.

  18. Rangaswamy M, Porjesz B (2008) Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes. Brain Research, 1235, 153-171. PMID: 18634760; PMCID: PMC2814598; DOI: 10.1016/j.brainres.2008.06.053.

  19. Saccone SF, Saccone NL, Swan GE, Madden PA, Goate AM, Rice JP, Bierut LJ (2008) Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence. Bioinformatics, 24(16), 1805-1811. PMID: 18565990; PMCID: PMC2610477; DOI: 10.1093/bioinformatics/btn315.

  20. Schuckit MA, Danko GP, Smith TL, Bierut LJ, Bucholz KK, Edenberg HJ, Hesselbrock V, Kramer J, Nurnberger JI, Jr., Trim R, Allen R, Kreikebaum S, Hinga B (2008) The prognostic implications of DSM-IV abuse criteria in drinking adolescents. Drug and Alcohol Dependence, 97(1-2), 94-104. PMID: 18479842; PMCID: PMC2581466; DOI: 10.1016/j.drugalcdep.2008.03.020.

  21. Schuckit MA, Smith TL, Hesselbrock V, Bucholz KK, Bierut L, Edenberg H, Kramer J, Longacre E, Fukukura T, Kalmijn J, Danko GP, Trim R (2008) Clinical implications of tolerance to alcohol in nondependent young drinkers. American Journal of Drug and Alcohol Abuse, 34(2), 133-149. PMID: 18293230; DOI: 10.1080/00952990701877003.

  22. Wetherill L, Schuckit MA, Hesselbrock V, Xuei X, Liang T, Dick DM, Kramer J, Nurnberger JI, Jr., Tischfield JA, Porjesz B, Edenberg HJ, Foroud T (2008) Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. Alcoholism: Clinical and Experimental Research, 32(12), 2031-2040. PMID: 18828811; PMCID: PMC2650441; DOI: 10.1111/j.1530-0277.2008.00790.x.

  23. Xuei X, Flury-Wetherill L, Almasy L, Bierut L, Tischfield J, Schuckit M, Nurnberger JI, Jr., Foroud T, Edenberg HJ (2008) Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence. Addiction Biology, 13(1), 80-87. PMID: 17910740; DOI: 10.1111/j.1369-1600.2007.00082.x.


2007 [23 Articles]

  1. Cavazos-Rehg PA, Spitznagel EL, Bucholz KK, Norberg K, Reich W, Nurnberger J, Jr., Hesselbrock V, Kramer J, Kuperman S, Bierut LJ (2007) The relationship between alcohol problems and dependence, conduct problems and diagnosis, and number of sex partners in a sample of young adults. Alcoholism: Clinical and Experimental Research, 31(12), 2046-2052. PMID: 18034697; DOI: 10.1111/j.1530-0277.2007.00537.x.

  2. Chen CT, Wang JC, Cohen BA (2007) The strength of selection on ultraconserved elements in the human genome. American Journal of Human Genetics, 80(4), 692-704. PMID: 17357075; PMCID: PMC1852725; DOI: 10.1086/513149.

  3. Chorlian DB, Tang Y, Rangaswamy M, O’Connor S, Rohrbaugh J, Taylor R, Porjesz B (2007) Heritability of EEG coherence in a large sib-pair population. Biological Psychology, 75(3), 260-266. PMID: 17498861; PMCID: PMC2270612; DOI: 10.1016/j.biopsycho.2007.03.006.

  4. Conner KR, Hesselbrock VM, Meldrum SC, Schuckit MA, Bucholz KK, Gamble SA, Wines JD, Jr., Kramer J (2007) Transitions to, and correlates of, suicidal ideation, plans, and unplanned and planned suicide attempts among 3,729 men and women with alcohol dependence. Journal of Studies on Alcohol and Drugs, 68(5), 654-662. PMID: 17690798; DOI: 10.15288/jsad.2007.68.654.

  5. Dick DM (2007) Identification of genes influencing a spectrum of externalizing psychopathology. Current Directions in Psychological Science, 16(6), 331-335. DOI: 10.1111/j.1467-8721.2007.00530.x.

  6. Dick DM, Agrawal A, Wang JC, Hinrichs A, Bertelsen S, Bucholz KK, Schuckit M, Kramer J, Nurnberger J, Jr., Tischfield J, Edenberg HJ, Goate A, Bierut LJ (2007) Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk. Addiction, 102(7), 1131-1139. PMID: 17567401; DOI: 10.1111/j.1360-0443.2007.01871.x.

  7. Dick DM, Aliev F, Kramer J, Wang JC, Hinrichs A, Bertelsen S, Kuperman S, Schuckit M, Nurnberger J, Jr., Edenberg HJ, Porjesz B, Begleiter H, Hesselbrock V, Goate A, Bierut L (2007) Association of CHRM2 with IQ: converging evidence for a gene influencing intelligence. Behavior Genetics, 37(2), 265-272. PMID: 17160701; DOI: 10.1007/s10519-006-9131-2.

  8. Dick DM, Plunkett J, Hamlin D, Nurnberger J, Jr., Kuperman S, Schuckit M, Hesselbrock V, Edenberg H, Bierut L (2007) Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Psychiatric Genetics, 17(1), 35-38. PMID: 17167343; DOI: 10.1097/YPG.0b013e328011188b.

  9. Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J, Jr., Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, Porjesz B, Begleiter H, Bierut LJ, Goate A (2007) Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. Alcoholism: Clinical and Experimental Research, 31(10), 1645-1653. PMID: 17850642; DOI: 10.1111/j.1530-0277.2007.00470.x.

  10. Foroud T, Wetherill LF, Dick DM, Hesselbrock V, Nurnberger JI, Jr., Kramer J, Tischfield J, Schuckit M, Bierut LJ, Xuei X, Edenberg HJ (2007) Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase. Alcoholism: Clinical and Experimental Research, 31(11), 1773-1779. PMID: 17850222; DOI: 10.1111/j.1530-0277.2007.00505.x.

  11. Foroud T, Wetherill LF, Liang T, Dick DM, Hesselbrock V, Kramer J, Nurnberger J, Schuckit M, Carr L, Porjesz B, Xuei X, Edenberg HJ (2007) Association of alcohol craving with alpha-synuclein (SNCA). Alcoholism: Clinical and Experimental Research, 31(4), 537-545. PMID: 17374032; DOI: 10.1111/j.1530-0277.2007.00337.x.

  12. Helzer JE, Bucholz KK, Gossop M (2007) A dimensional option for the diagnosis of substance dependence in DSM-V. International Journal of Methods in Psychiatric Research, 16 Suppl 1(Suppl 1), S24-33. PMID: 17623392; PMCID: PMC6879089; DOI: 10.1002/mpr.210.

  13. Hesselbrock VM, Hesselbrock MN (2007) Are there empirically supported and clinically useful subtypes of alcohol dependence? In: Schuckit MA, Sirovatka P, Regier DA (eds.): Diagnostic issues in substance use disorders, American Psychiatric Association, pp. 171-182.

  14. Nurnberger JI, Jr., Bierut LJ (2007) Seeking the connections: alcoholism and our genes. Scientific American, 296(4), 46-53. PMID: 17479630; DOI: 10.1038/scientificamerican0407-46.

  15. Porjesz B, Li TK (2007) Impulsivity and addiction: a tribute to Henri Begleiter. ScientificWorldJournal, 7, 121-123. PMID: 17982584; PMCID: PMC5901192; DOI: 10.1100/tsw.2007.259.

  16. Porjesz B, Rangaswamy M (2007) Neurophysiological endophenotypes, CNS disinhibition, and risk for alcohol dependence and related disorders. ScientificWorldJournal, 7, 131-141. PMID: 17982586; PMCID: PMC5901350; DOI: 10.1100/tsw.2007.203.

  17. Rangaswamy M, Jones KA, Porjesz B, Chorlian DB, Padmanabhapillai A, Kamarajan C, Kuperman S, Rohrbaugh J, O’Connor SJ, Bauer LO, Schuckit MA, Begleiter H (2007) Delta and theta oscillations as risk markers in adolescent offspring of alcoholics. International Journal of Psychophysiology, 63(1), 3-15. PMID: 17129626; PMCID: PMC2020838; DOI: 10.1016/j.ijpsycho.2006.10.003.

  18. Schuckit MA, Smith TL, Danko GP, Pierson J, Hesselbrock V, Bucholz KK, Kramer J, Kuperman S, Dietiker C, Brandon R, Chan G (2007) The ability of the Self-Rating of the Effects of Alcohol (SRE) Scale to predict alcohol-related outcomes five years later. Journal of Studies on Alcohol and Drugs, 68(3), 371-378. PMID: 17446976; DOI: 10.15288/jsad.2007.68.371.

  19. Schuckit MA, Smith TL, Danko GP, Pierson J, Trim R, Nurnberger JI, Kramer J, Kuperman S, Bierut LJ, Hesselbrock V (2007) A comparison of factors associated with substance-induced versus independent depressions. Journal of Studies on Alcohol and Drugs, 68(6), 805-812. PMID: 17960298; DOI: 10.15288/jsad.2007.68.805.

  20. Tang Y, Chorlian DB, Rangaswamy M, O’Connor S, Taylor R, Rohrbaugh J, Porjesz B, Begleiter H (2007) Heritability of bipolar EEG spectra in a large sib-pair population. Behavior Genetics, 37(2), 302-313. PMID: 17180712; DOI: 10.1007/s10519-006-9133-0.

  21. Tang Y, Chorlian DB, Rangaswamy M, Porjesz B, Bauer L, Kuperman S, O’Connor S, Rohrbaugh J, Schuckit M, Stimus A, Begleiter H (2007) Genetic influences on bipolar EEG power spectra. International Journal of Psychophysiology, 65(1), 2-9. PMID: 17383039; DOI: 10.1016/j.ijpsycho.2007.02.004.

  22. Wang JC, Hinrichs AL, Bertelsen S, Stock H, Budde JP, Dick DM, Bucholz KK, Rice J, Saccone N, Edenberg HJ, Hesselbrock V, Kuperman S, Schuckit MA, Bierut LJ, Goate AM (2007) Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. Alcoholism: Clinical and Experimental Research, 31(2), 209-215. PMID: 17250611; DOI: 10.1111/j.1530-0277.2006.00297.x.

  23. Xuei X, Flury-Wetherill L, Bierut L, Dick D, Nurnberger J, Jr., Foroud T, Edenberg HJ (2007) The opioid system in alcohol and drug dependence: family-based association study. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 144B(7), 877-884. PMID: 17503481; DOI: 10.1002/ajmg.b.30531.


2006 [35 Articles]

  1. Agrawal A, Edenberg HJ, Foroud T, Bierut LJ, Dunne G, Hinrichs AL, Nurnberger JI, Crowe R, Kuperman S, Schuckit MA, Begleiter H, Porjesz B, Dick DM (2006) Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behavior Genetics, 36(5), 640-650. PMID: 16622805; DOI: 10.1007/s10519-006-9069-4.

  2. Begleiter H, Porjesz B (2006) Genetics of human brain oscillations. International Journal of Psychophysiology, 60(2), 162-171. PMID: 16540194; DOI: 10.1016/j.ijpsycho.2005.12.013.

  3. Bucholz KK, Nurnberger JI, Jr., Kramer JR, Hesselbrock VM, Schuckit MA, Bierut LJ (2006) Comparison of psychiatric diagnoses from interview reports with those from best-estimate procedures. Journal of Studies on Alcohol, 67(1), 157-168. PMID: 16536140; DOI: 10.15288/jsa.2006.67.157.

  4. Conner KR, Hesselbrock VM, Schuckit MA, Hirsch JK, Knox KL, Meldrum S, Bucholz KK, Kramer J, Kuperman S, Preuss U, Soyka M (2006) Precontemplated and impulsive suicide attempts among individuals with alcohol dependence. Journal of Studies on Alcohol, 67(1), 95-101. PMID: 16536133; DOI: 10.15288/jsa.2006.67.95.

  5. Dick DM, Agrawal A, Schuckit MA, Bierut L, Hinrichs A, Fox L, Mullaney J, Cloninger CR, Hesselbrock V, Nurnberger JI, Jr., Almasy L, Foroud T, Porjesz B, Edenberg H, Begleiter H (2006) Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction. Journal of Studies on Alcohol, 67(2), 185-194. PMID: 16562401; DOI: 10.15288/jsa.2006.67.185.

  6. Dick DM, Aliev F, Bierut L, Goate A, Rice J, Hinrichs A, Bertelsen S, Wang JC, Dunn G, Kuperman S, Schuckit M, Nurnberger J, Jr., Porjesz B, Beglieter H, Kramer J, Hesselbrock V (2006) Linkage analyses of IQ in the collaborative study on the genetics of alcoholism (COGA) sample. Behavior Genetics, 36(1), 77-86. PMID: 16341907; DOI: 10.1007/s10519-005-9009-8.

  7. Dick DM, Bierut L, Hinrichs A, Fox L, Bucholz KK, Kramer J, Kuperman S, Hesselbrock V, Schuckit M, Almasy L, Tischfield J, Porjesz B, Begleiter H, Nurnberger J, Jr., Xuei X, Edenberg HJ, Foroud T (2006) The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behavior Genetics, 36(4), 577-590. PMID: 16557364; DOI: 10.1007/s10519-005-9041-8.

  8. Dick DM, Bierut LJ (2006) The genetics of alcohol dependence. Current Psychiatry Reports, 8(2), 151-157. PMID: 16539893; DOI: 10.1007/s11920-006-0015-1.

  9. Dick DM, Jones K, Saccone N, Hinrichs A, Wang JC, Goate A, Bierut L, Almasy L, Schuckit M, Hesselbrock V, Tischfield J, Foroud T, Edenberg H, Porjesz B, Begleiter H (2006) Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behavior Genetics, 36(1), 112-126. PMID: 16341909; DOI: 10.1007/s10519-005-9001-3.

  10. Dick DM, Plunkett J, Wetherill LF, Xuei X, Goate A, Hesselbrock V, Schuckit M, Crowe R, Edenberg HJ, Foroud T (2006) Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample. Alcoholism: Clinical and Experimental Research, 30(7), 1101-1110. PMID: 16792556; DOI: 10.1111/j.1530-0277.2006.00136.x.

  11. Duncan AE, Neuman RJ, Kramer JR, Kuperman S, Hesselbrock VM, Bucholz KK (2006) Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women. Drug and Alcohol Dependence, 84(1), 122-132. PMID: 16455211; DOI: 10.1016/j.drugalcdep.2006.01.005.

  12. Edenberg HJ, Foroud T (2006) The genetics of alcoholism: identifying specific genes through family studies. Addiction Biology, 11(3-4), 386-396. PMID: 16961766; DOI: 10.1111/j.1369-1600.2006.00035.x.

  13. Edenberg HJ, Xuei X, Chen HJ, Tian H, Wetherill LF, Dick DM, Almasy L, Bierut L, Bucholz KK, Goate A, Hesselbrock V, Kuperman S, Nurnberger J, Porjesz B, Rice J, Schuckit M, Tischfield J, Begleiter H, Foroud T (2006) Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Human Molecular Genetics, 15(9), 1539-1549. PMID: 16571603; DOI: 10.1093/hmg/ddl073.

  14. Fisher SL, Bucholz KK, Reich W, Fox L, Kuperman S, Kramer J, Hesselbrock V, Dick DM, Nurnberger JI, Jr., Edenberg HJ, Bierut LJ (2006) Teenagers are right–parents do not know much: an analysis of adolescent-parent agreement on reports of adolescent substance use, abuse, and dependence. Alcoholism: Clinical and Experimental Research, 30(10), 1699-1710. PMID: 17010137; DOI: 10.1111/j.1530-0277.2006.00205.x.

  15. Gogineni A, King S, Jackson K, Kramer J, Bucholz K, Chan G, Iacono W, Kuperman S, Larkins JM, Longabaugh R, McGue M, Polgreen L, Sher KJ, Stout R, Strong D, Woolard R (2006) Female offspring of alcoholic individuals: recent findings on alcoholism and psychopathology risks: symposium presented at the Research Society on Alcoholism, 2004, Vancouver Aruna Gogineni, Chair. Alcoholism: Clinical and Experimental Research, 30(2), 377-387. PMID: 16441287; DOI: 10.1111/j.1530-0277.2006.00042.x.

  16. Grucza RA, Bierut LJ (2006) Cigarette smoking and the risk for alcohol use disorders among adolescent drinkers. Alcoholism: Clinical and Experimental Research, 30(12), 2046-2054. PMID: 17117970; PMCID: PMC2431150; DOI: 10.1111/j.1530-0277.2006.00255.x.

  17. Grucza RA, Bierut LJ (2006) Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. Alcohol Research and Health, 29(3), 172-178. PMID: 17373405; PMCID: PMC6527048; LINK.

  18. Grucza RA, Robert Cloninger C, Bucholz KK, Constantino JN, Schuckit MI, Dick DM, Bierut LJ (2006) Novelty seeking as a moderator of familial risk for alcohol dependence. Alcoholism: Clinical and Experimental Research, 30(7), 1176-1183. PMID: 16792565; DOI: 10.1111/j.1530-0277.2006.00133.x.

  19. Hayden EP, Wiegand RE, Meyer ET, Bauer LO, O’Connor S J, Nurnberger JI, 2nd, Chorlian DB, Porjesz B, Begleiter H (2006) Patterns of regional brain activity in alcohol-dependent subjects. Alcoholism: Clinical and Experimental Research, 30(12), 1986-1991. PMID: 17117963; DOI: 10.1111/j.1530-0277.2006.00244.x.

  20. Helzer JE, Bucholz KK, Bierut LJ, Regier DA, Schuckit MA, Guth SE (2006) Should DSM-V include dimensional diagnostic criteria for alcohol use disorders? Alcoholism: Clinical and Experimental Research, 30(2), 303-310. PMID: 16441279; DOI: 10.1111/j.1530-0277.2006.00028.x.

  21. Hesselbrock VM, Hesselbrock MN (2006) Are there empirically supported and clinically useful subtypes of alcohol dependence? Addiction, 101 Suppl 1, 97-103. PMID: 16930165; DOI: 10.1111/j.1360-0443.2006.01596.x.

  22. Hesselbrock VM, Hesselbrock MN (2006) Developmental perspectives on the risk for developing substance abuse problems. In: Miller WR, Carroll KM (eds.): Rethinking substance abuse: What the science shows and what we should do about it, Guilford Press, New York, USA, pp. 97-114.

  23. Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM (2006) Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. American Journal of Human Genetics, 78(1), 103-111. PMID: 16385453; PMCID: PMC1380207; DOI: 10.1086/499253.

  24. Johnson C, Drgon T, Liu QR, Walther D, Edenberg H, Rice J, Foroud T, Uhl GR (2006) Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 141B(8), 844-853. PMID: 16894614; PMCID: PMC3922200; DOI: 10.1002/ajmg.b.30346.

  25. Jones A, Christiansen P, Nederkoorn C, Houben K, Field M (2013) Fluctuating disinhibition: implications for the understanding and treatment of alcohol and other substance use disorders. Front Psychiatry, 4(140), 140. PMID: 24155728; PMCID: PMC3804868; DOI: 10.3389/fpsyt.2013.00140.

  26. Jones KA, Porjesz B, Almasy L, Bierut L, Dick D, Goate A, Hinrichs A, Rice JP, Wang JC, Bauer LO, Crowe R, Foroud T, Hesselbrock V, Kuperman S, Nurnberger J, Jr., O’Connor SJ, Rohrbaugh J, Schuckit MA, Tischfield J, Edenberg HJ, Begleiter H (2006) A cholinergic receptor gene (CHRM2) affects event-related oscillations. Behavior Genetics, 36(5), 627-639. PMID: 16823639; DOI: 10.1007/s10519-006-9075-6.

  27. Jones KA, Porjesz B, Chorlian D, Rangaswamy M, Kamarajan C, Padmanabhapillai A, Stimus A, Begleiter H (2006) S-transform time-frequency analysis of P300 reveals deficits in individuals diagnosed with alcoholism. Clinical Neurophysiology, 117(10), 2128-2143. PMID: 16926113; DOI: 10.1016/j.clinph.2006.02.028.

  28. Kamarajan C, Porjesz B, Jones K, Chorlian D, Padmanabhapillai A, Rangaswamy M, Stimus A, Begleiter H (2006) Event-related oscillations in offspring of alcoholics: neurocognitive disinhibition as a risk for alcoholism. Biological Psychiatry, 59(7), 625-634. PMID: 16213472; PMCID: PMC3766847; DOI: 10.1016/j.biopsych.2005.08.017.

  29. Ohannessian CM, Hesselbrock VM, Ruddy K, Kramer J (2006) Parental substance use and adolescent adjustment: A micro-level approach. The Prevention Researcher, 13(4), 7-9. LINK.

  30. Padmanabhapillai A, Porjesz B, Ranganathan M, Jones KA, Chorlian DB, Tang Y, Kamarajan C, Rangaswamy M, Stimus A, Begleiter H (2006) Suppression of early evoked gamma band response in male alcoholics during a visual oddball task. International Journal of Psychophysiology, 60(1), 15-26. PMID: 16019097; DOI: 10.1016/j.ijpsycho.2005.03.026.

  31. Padmanabhapillai A, Tang Y, Ranganathan M, Rangaswamy M, Jones KA, Chorlian DB, Kamarajan C, Stimus A, Kuperman S, Rohrbaugh J, O’Connor SJ, Bauer LO, Schuckit MA, Begleiter H, Porjesz B (2006) Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task. International Journal of Psychophysiology, 62(2), 262-271. PMID: 16887227; DOI: 10.1016/j.ijpsycho.2006.05.012.

  32. Schuckit MA, Windle M, Smith TL, Hesselbrock V, Ohannessian C, Averna S, Bauer L, Kramer J, Bucholz K, Sher KJ (2006) Searching for the full picture: structural equation modeling in alcohol research. Alcoholism: Clinical and Experimental Research, 30(2), 194-202. PMID: 16441268; DOI: 10.1111/j.1530-0277.2006.00031.x.

  33. Volkow ND, Wang GJ, Begleiter H, Porjesz B, Fowler JS, Telang F, Wong C, Ma Y, Logan J, Goldstein R, Alexoff D, Thanos PK (2006) High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors. Archives of General Psychiatry, 63(9), 999-1008. PMID: 16953002; DOI: 10.1001/archpsyc.63.9.999.

  34. Wang K, Porjesz B, Jones K, Begleiter H (2006) Genetic linkage and linkage disequilibrium analysis. In: Chow S-C (ed.): Encyclopedia of Biopharmaceutical Statistics, Taylor and Francis, New York, pp. 1-12.

  35. Xuei X, Dick D, Flury-Wetherill L, Tian HJ, Agrawal A, Bierut L, Goate A, Bucholz K, Schuckit M, Nurnberger J, Jr., Tischfield J, Kuperman S, Porjesz B, Begleiter H, Foroud T, Edenberg HJ (2006) Association of the kappa-opioid system with alcohol dependence. Molecular Psychiatry, 11(11), 1016-1024. PMID: 16924269; DOI: 10.1038/sj.mp.4001882.


2005 [24 Articles]

  1. Bailey-Wilson JE, Almasy L, de Andrade M, Bailey J, Bickeboller H, Cordell HJ, Daw EW, Goldin L, Goode EL, Gray-McGuire C, Hening W, Jarvik G, Maher BS, Mendell N, Paterson AD, Rice J, Satten G, Suarez B, Vieland V, Wilcox M, Zhang H, Ziegler A, MacCluer JW (2005) Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans. BMC Genetics, 6 Suppl 1(Suppl 1), S1. PMID: 16451554; PMCID: PMC1866841; DOI: 10.1186/1471-2156-6-S1-S1.

  2. Ceballos NA, Houston RJ, Smith ND, Bauer LO, Taylor RE (2005) N400 as an index of semantic expectancies: differential effects of alcohol and cocaine dependence. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29(6), 936-943. PMID: 15967560; DOI: 10.1016/j.pnpbp.2005.04.036.

  3. Corbett J, Saccone NL, Foroud T, Goate A, Edenberg H, Nurnberger J, Porjesz B, Begleiter H, Reich T, Rice JP (2005) A sex-adjusted and age-adjusted genome screen for nested alcohol dependence diagnoses. Psychiatric Genetics, 15(1), 25-30. PMID: 15722954; DOI: 10.1097/00041444-200503000-00005.

  4. Culverhouse R, Bucholz KK, Crowe RR, Hesselbrock V, Nurnberger JI, Jr., Porjesz B, Schuckit MA, Reich T, Bierut LJ (2005) Long-term stability of alcohol and other substance dependence diagnoses and habitual smoking: an evaluation after 5 years. Archives of General Psychiatry, 62(7), 753-760. PMID: 15997016; DOI: 10.1001/archpsyc.62.7.753.

  5. Dick DM, Edenberg HJ, Xuei X, Goate A, Hesselbrock V, Schuckit M, Crowe R, Foroud T (2005) No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 132B(1), 24-28. PMID: 15690551; DOI: 10.1002/ajmg.b.30058.

  6. Duncan AE, Neuman RJ, Kramer J, Kuperman S, Hesselbrock V, Reich T, Bucholz KK (2005) Are there subgroups of bulimia nervosa based on comorbid psychiatric disorders? International Journal of Eating Disorders, 37(1), 19-25. PMID: 15690461; DOI: 10.1002/eat.20066.

  7. Dunn G, Hinrichs AL, Bertelsen S, Jin CH, Kauwe JS, Suarez BK, Bierut LJ (2005) Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures. BMC Genetics, 6 Suppl 1(Suppl 1), S122. PMID: 16451580; PMCID: PMC1866815; DOI: 10.1186/1471-2156-6-S1-S122.

  8. Edenberg HJ, Bierut LJ, Boyce P, Cao M, Cawley S, Chiles R, Doheny KF, Hansen M, Hinrichs T, Jones K, Kelleher M, Kennedy GC, Liu G, Marcus G, McBride C, Murray SS, Oliphant A, Pettengill J, Porjesz B, Pugh EW, Rice JP, Rubano T, Shannon S, Steeke R, Tischfield JA, Tsai YY, Zhang C, Begleiter H (2005) Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. BMC Genetics, 6 Suppl 1(Suppl 1), S2. PMID: 16451628; PMCID: PMC1866767; DOI: 10.1186/1471-2156-6-S1-S2.

  9. Eng MY, Schuckit MA, Smith TL (2005) The level of response to alcohol in daughters of alcoholics and controls. Drug and Alcohol Dependence, 79(1), 83-93. PMID: 15943947; DOI: 10.1016/j.drugalcdep.2005.01.002.

  10. Hesselbrock V, Higuchi S, Soyka M (2005) Recent developments in the genetics of alcohol-related phenotypes. Alcoholism: Clinical and Experimental Research, 29(7), 1321-1324. PMID: 16088995; DOI: 10.1097/01.alc.0000171955.52431.e7.

  11. Hinrichs AL, Bertelsen S, Bierut LJ, Dunn G, Jin CH, Kauwe JS, Suarez BK (2005) Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps. BMC Genetics, 6 Suppl 1(Suppl 1), S34. PMID: 16451644; PMCID: PMC1866751; DOI: 10.1186/1471-2156-6-S1-S34.

  12. Hinrichs AL, Suarez BK (2005) Genotyping errors, pedigree errors, and missing data. Genetic Epidemiology, 29 Suppl 1, S120-124. PMID: 16342180; DOI: 10.1002/gepi.20120.

  13. Kamarajan C, Porjesz B, Jones KA, Choi K, Chorlian DB, Padmanabhapillai A, Rangaswamy M, Stimus AT, Begleiter H (2005) Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task. Biological Psychology, 69(3), 353-373. PMID: 15925035; PMCID: PMC3758477; DOI: 10.1016/j.biopsycho.2004.08.004.

  14. Kamarajan C, Porjesz B, Jones KA, Chorlian DB, Padmanabhapillai A, Rangaswamy M, Stimus AT, Begleiter H (2005) Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism. Clinical Neurophysiology, 116(5), 1049-1061. PMID: 15826845; PMCID: PMC3785104; DOI: 10.1016/j.clinph.2004.12.015.

  15. Kauwe JS, Bertelsen S, Bierut LJ, Dunn G, Hinrichs AL, Jin CH, Suarez BK (2005) The efficacy of short tandem repeat polymorphisms versus single-nucleotide polymorphisms for resolving population structure. BMC Genetics, 6 Suppl 1(Suppl 1), S84. PMID: 16451699; PMCID: PMC1866696; DOI: 10.1186/1471-2156-6-S1-S84.

  16. Kuperman S, Chan G, Kramer JR, Bierut L, Bucholz KK, Fox L, Hesselbrock V, Numberger JI, Jr., Reich T, Reich W, Schuckit MA, Collaborative Study on the Genetics of Alcoholism (2005) Relationship of age of first drink to child behavioral problems and family psychopathology. Alcoholism: Clinical and Experimental Research, 29(10), 1869-1876. PMID: 16269917; DOI: 10.1097/01.alc.0000183190.32692.c7.

  17. Ohannessian CM, Hesselbrook VM, Kramer J, Kuperman S, Bucholz KK, Schuckit MA, Nurnberger JI (2005) The relationship between parental psychopathology and adolescent psychopathology: An examination of gender patterns. Journal of Emotional and Behavioral Disorders, 13(2), 67-76. DOI: Doi 10.1177/10634266050130020101.

  18. Porjesz B, Rangaswamy M, Kamarajan C, Jones KA, Padmanabhapillai A, Begleiter H (2005) The utility of neurophysiological markers in the study of alcoholism. Clinical Neurophysiology, 116(5), 993-1018. PMID: 15826840; DOI: 10.1016/j.clinph.2004.12.016.

  19. Rice JP, Saccone SF (2005) Alcoholism and related traits: a summary of Group 13 contributions. Genetic Epidemiology, 29 Suppl 1, S96-S102. PMID: 16342188; DOI: 10.1002/gepi.20116.

  20. Saccone SF, Saccone NL, Neuman RJ, Rice JP (2005) Genetic analysis of the maximum drinks phenotype. BMC Genetics, 6 Suppl 1(Suppl 1), S124. PMID: 16451582; PMCID: PMC1866813; DOI: 10.1186/1471-2156-6-S1-S124.

  21. Schuckit MA, Smith TL, Danko G, Kuperman S, Bierut LJ, Hesselbrock V (2005) Correlations among first-degree relatives for responses on the Self-Rating of the Effects of Alcohol Questionnaire in teenagers. Journal of Studies on Alcohol, 66(1), 62-65. PMID: 15830904; DOI: 10.15288/jsa.2005.66.62.

  22. Schuckit MA, Smith TL, Danko GP, Anderson KG, Brown SA, Kuperman S, Kramer J, Hesselbrock V, Bucholz K (2005) Evaluation of a level of response to alcohol-based structural equation model in adolescents. Journal of Studies on Alcohol, 66(2), 174-184. PMID: 15957668; DOI: 10.15288/jsa.2005.66.174.

  23. Schuckit MA, Smith TL, Danko GP, Kramer J, Godinez J, Bucholz KK, Nurnberger JI, Jr., Hesselbrock V (2005) Prospective evaluation of the four DSM-IV criteria for alcohol abuse in a large population. American Journal of Psychiatry, 162(2), 350-360. PMID: 15677601; DOI: 10.1176/appi.ajp.162.2.350.

  24. Suarez BK, Taylor C, Bertelsen S, Bierut LJ, Dunn G, Jin CH, Kauwe JS, Paterson AD, Hinrichs AL (2005) An analysis of identical single-nucleotide polymorphisms genotyped by two different platforms. BMC Genetics, 6 Suppl 1(Suppl 1), S152. PMID: 16451613; PMCID: PMC1866782; DOI: 10.1186/1471-2156-6-S1-S152.


2004 [16 Articles]

  1. Bierut LJ, Rice JP, Goate A, Hinrichs AL, Saccone NL, Foroud T, Edenberg HJ, Cloninger CR, Begleiter H, Conneally PM, Crowe RR, Hesselbrock V, Li TK, Nurnberger JI, Jr., Porjesz B, Schuckit MA, Reich T (2004) A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. American Journal of Medical Genetics. Part A, 124A(1), 19-27. PMID: 14679582; DOI: 10.1002/ajmg.a.20329.

  2. Dick DM, Edenberg HJ, Xuei X, Goate A, Kuperman S, Schuckit M, Crowe R, Smith TL, Porjesz B, Begleiter H, Foroud T (2004) Association of GABRG3 with alcohol dependence. Alcoholism: Clinical and Experimental Research, 28(1), 4-9. PMID: 14745296; DOI: 10.1097/01.ALC.0000108645.54345.98.

  3. Dick DM, Li TK, Edenberg HJ, Hesselbrock V, Kramer J, Kuperman S, Porjesz B, Bucholz K, Goate A, Nurnberger J, Foroud T (2004) A genome-wide screen for genes influencing conduct disorder. Molecular Psychiatry, 9(1), 81-86. PMID: 14699444; DOI: 10.1038/sj.mp.4001368.

  4. Edenberg HJ, Dick DM, Xuei X, Tian H, Almasy L, Bauer LO, Crowe RR, Goate A, Hesselbrock V, Jones K, Kwon J, Li TK, Nurnberger JI, Jr., O’Connor SJ, Reich T, Rice J, Schuckit MA, Porjesz B, Foroud T, Begleiter H (2004) Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. American Journal of Human Genetics, 74(4), 705-714. PMID: 15024690; PMCID: PMC1181946; DOI: 10.1086/383283.

  5. Hesselbrock V, Dick D, Hesselbrock M, Foroud T, Schuckit M, Edenberg H, Bucholz K, Kramer J, Reich T, Goate A, Bierut L, Rice JP, Nurnberger JI, Jr. (2004) The search for genetic risk factors associated with suicidal behavior. Alcoholism: Clinical and Experimental Research, 28(5 Suppl), 70S-76S. PMID: 15166638; DOI: 10.1097/01.alc.0000127416.92128.b0.

  6. Jones KA, Porjesz B, Almasy L, Bierut L, Goate A, Wang JC, Dick DM, Hinrichs A, Kwon J, Rice JP, Rohrbaugh J, Stock H, Wu W, Bauer LO, Chorlian DB, Crowe RR, Edenberg HJ, Foroud T, Hesselbrock V, Kuperman S, Nurnberger J, Jr., O’Connor SJ, Schuckit MA, Stimus AT, Tischfield JA, Reich T, Begleiter H (2004) Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition. International Journal of Psychophysiology, 53(2), 75-90. PMID: 15210286; DOI: 10.1016/j.ijpsycho.2004.02.004.

  7. Kamarajan C, Porjesz B, Jones KA, Choi K, Chorlian DB, Padmanabhapillai A, Rangaswamy M, Stimus AT, Begleiter H (2004) The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism. International Journal of Psychophysiology, 51(2), 155-180. PMID: 14693365; PMCID: PMC3766846; DOI: 10.1016/j.ijpsycho.2003.09.004.

  8. Nurnberger JI, Jr., Wiegand R, Bucholz K, O’Connor S, Meyer ET, Reich T, Rice J, Schuckit M, King L, Petti T, Bierut L, Hinrichs AL, Kuperman S, Hesselbrock V, Porjesz B (2004) A family study of alcohol dependence: coaggregation of multiple disorders in relatives of alcohol-dependent probands. Archives of General Psychiatry, 61(12), 1246-1256. PMID: 15583116; DOI: 10.1001/archpsyc.61.12.1246.

  9. Ohannessian CM, Hesselbrock VM, Kramer J, Bucholz KK, Schuckit MA, Kuperman S, Nurnberger JI, Jr. (2004) Parental substance use consequences and adolescent psychopathology. Journal of Studies on Alcohol, 65(6), 725-730. PMID: 15700509; DOI: 10.15288/jsa.2004.65.725.

  10. Ohannessian CM, Hesselbrock VM, Kramer J, Kuperman S, Bucholz KK, Schuckit MA, Nurnberger JI, Jr. (2004) The relationship between parental alcoholism and adolescent psychopathology: a systematic examination of parental comorbid psychopathology. Journal of Abnormal Child Psychology, 32(5), 519-533. PMID: 15500031; DOI: 10.1023/b:jacp.0000037781.49155.a6.

  11. Polich J, Ochoa CJ (2004) Alcoholism risk, tobacco smoking, and P300 event-related potential. Clinical Neurophysiology, 115(6), 1374-1383. PMID: 15134705; DOI: 10.1016/j.clinph.2004.01.026.

  12. Porjesz B, Jones K, Begleiter H (2004) The genetics of oscillations in the human brain. In: Hallett M, Phillips Ii LH, Schomer DL, Massey JM (eds.): Advances in Clinical Neurophysiology (Supplements to Clinical Neurophysiology, Volume 57), Elsevier, Amsterdam, pp. 441-449. DOI: 10.1016/s1567-424x(09)70382-4.

  13. Rangaswamy M, Porjesz B, Ardekani BA, Choi SJ, Tanabe JL, Lim KO, Begleiter H (2004) A functional MRI study of visual oddball: evidence for frontoparietal dysfunction in subjects at risk for alcoholism. Neuroimage, 21(1), 329-339. PMID: 14741671; DOI: 10.1016/j.neuroimage.2003.09.018.

  14. Rangaswamy M, Porjesz B, Chorlian DB, Wang K, Jones KA, Kuperman S, Rohrbaugh J, O’Connor SJ, Bauer LO, Reich T, Begleiter H (2004) Resting EEG in offspring of male alcoholics: beta frequencies. International Journal of Psychophysiology, 51(3), 239-251. PMID: 14962576; DOI: 10.1016/j.ijpsycho.2003.09.003.

  15. Stassen H, Begleiter H, Beirut L, Culverhouse R, Hinrichs T, Porjesz B, Rice J, Scharfetter C, Reich T (2004) Oligogenic approaches to the predisposition of alcohol dependence – A genome-wide search on 255 families. Neurology, Psychiatry and Brain Research, 11(1), 13-22. LINK.

  16. Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S, Kwon JM, Wu W, Dick DM, Rice J, Jones K, Nurnberger JI, Jr., Tischfield J, Porjesz B, Edenberg HJ, Hesselbrock V, Crowe R, Schuckit M, Begleiter H, Reich T, Goate AM, Bierut LJ (2004) Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Human Molecular Genetics, 13(17), 1903-1911. PMID: 15229186; DOI: 10.1093/hmg/ddh194.


2003 [15 Articles]

  1. Almasy L (2003) Quantitative risk factors as indices of alcoholism susceptibility. Annals of Medicine, 35(5), 337-343. PMID: 12952020; DOI: 10.1080/07853890310004903.

  2. Chorlian DB, Porjesz B, Begleiter H (2003) Determination of human EEG alpha entrainment ERD/ERS using the continuous complex wavelet transform. Independent Component Analyses, Wavelets, and Neural Networks, 5102, 145-155. DOI: 10.1117/12.485937.

  3. Dick DM, Foroud T (2003) Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcoholism: Clinical and Experimental Research, 27(5), 868-879. PMID: 12766633; DOI: 10.1097/01.ALC.0000065436.24221.63.

  4. Foroud T, Nurnberger JI, Jr., (2003) Genetics of Addictive Disorders. In: Soares J, Gershon S (eds.): Handbook of Medical Psychiatry, CRC Press, pp. 638-655; LINK.

  5. Ghosh S, Begleiter H, Porjesz B, Chorlian DB, Edenberg HJ, Foroud T, Goate A, Reich T (2003) Linkage mapping of beta 2 EEG waves via non-parametric regression. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 118B(1), 66-71. PMID: 12627469; DOI: 10.1002/ajmg.b.10057.

  6. Hesselbrock MN, Hesselbrock VM, Segal B, Schuckit MA, Bucholz K (2003) Ethnicity and psychiatric comorbidity among alcohol-dependent persons who receive inpatient treatment: African Americans, Alaska natives, Caucasians, and Hispanics. Alcoholism: Clinical and Experimental Research, 27(8), 1368-1373. PMID: 12966342; DOI: 10.1097/01.ALC.0000080164.21934.F9.

  7. Hesselbrock VM, Hesselbrock MN, Segal B (2003) Alcohol dependence among Alaskan natives and their health care utilization. Alcoholism: Clinical and Experimental Research, 27(8), 1353-1355. PMID: 12966338; DOI: 10.1097/01.ALC.0000080167.17411.21.

  8. Porjesz B, Begleiter H (2003) Alcoholism and human electrophysiology. Alcohol Research and Health, 27(2), 153-160. PMID: 15303626; PMCID: PMC6668890; LINK.

  9. Preuss UW, Schuckit MA, Smith TL, Danko GP, Bucholz KK, Hesselbrock MN, Hesselbrock V, Kramer JR (2003) Predictors and correlates of suicide attempts over 5 years in 1,237 alcohol-dependent men and women. American Journal of Psychiatry, 160(1), 56-63. PMID: 12505802; DOI: 10.1176/appi.ajp.160.1.56.

  10. Rangaswamy M, Porjesz B, Chorlian DB, Choi K, Jones KA, Wang K, Rohrbaugh J, O’Connor S, Kuperman S, Reich T, Begleiter H (2003) Theta power in the EEG of alcoholics. Alcoholism: Clinical and Experimental Research, 27(4), 607-615. PMID: 12711923; DOI: 10.1097/01.ALC.0000060523.95470.8F.

  11. Rice J, Saccone M, Foroud T, Edenberg H, Nurnberger Jr J, Goate A, Crowe R, Hesselbrock V, Schuckit M, Porjesz B (2003) Alcoholism: the USA Collaborative Study on the Genetics of Alcoholism (COGA). In: Cooper DN (ed.): Encyclopedia of the Human Genome. Macmillan Publishers Ltd, Nature Publishing Group, pp. 1-7.

  12. Rice JP, Neuman RJ, Saccone NL, Corbett J, Rochberg N, Hesselbrock V, Bucholz KK, McGuffin P, Reich T (2003) Age and birth cohort effects on rates of alcohol dependence. Alcoholism: Clinical and Experimental Research, 27(1), 93-99. PMID: 12544012; DOI: 10.1097/01.ALC.0000047303.89421.AA.

  13. Song J, Koller DL, Foroud T, Carr K, Zhao J, Rice J, Nurnberger JI, Jr., Begleiter H, Porjesz B, Smith TL, Schuckit MA, Edenberg HJ (2003) Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 117B(1), 39-45. PMID: 12555233; DOI: 10.1002/ajmg.b.10022.

  14. Suresh S, Porjesz B, Chorlian DB, Choi K, Jones KA, Wang K, Stimus A, Begleiter H (2003) Auditory P3 in female alcoholics. Alcoholism: Clinical and Experimental Research, 27(7), 1064-1074. PMID: 12878912; DOI: 10.1097/01.ALC.0000075549.49800.A0.

  15. Wilhelmsen KC, Schuckit M, Smith TL, Lee JV, Segall SK, Feiler HS, Kalmijn J (2003) The search for genes related to a low-level response to alcohol determined by alcohol challenges. Alcoholism: Clinical and Experimental Research, 27(7), 1041-1047. PMID: 12878909; DOI: 10.1097/01.ALC.0000075551.02714.63.


2002 [19 Articles]

  1. Ardekani BA, Choi SJ, Hossein-Zadeh GA, Porjesz B, Tanabe JL, Lim KO, Bilder R, Helpern JA, Begleiter H (2002) Functional magnetic resonance imaging of brain activity in the visual oddball task. Brain Research: Cognitive Brain Research, 14(3), 347-356. PMID: 12421658; DOI: 10.1016/s0926-6410(02)00137-4.

  2. Bierut LJ, Saccone NL, Rice JP, Goate A, Foroud T, Edenberg H, Almasy L, Conneally PM, Crowe R, Hesselbrock V, Li TK, Nurnberger J, Jr., Porjesz B, Schuckit MA, Tischfield J, Begleiter H, Reich T (2002) Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. Alcohol Research and Health, 26(3), 208-213. PMID: 12875049; PMCID: PMC6683836; LINK.

  3. Cohen HL, Ji J, Chorlian DB, Begleiter H, Porjesz B (2002) Alcohol-related ERP changes recorded from different modalities: a topographic analysis. Alcoholism: Clinical and Experimental Research, 26(3), 303-317. PMID: 11923582; DOI: 10.1111/j.1530-0277.2002.tb02539.x.

  4. Dick DM, Foroud T (2002) Genetic strategies to detect genes involved in alcoholism and alcohol-related traits. Alcohol Research and Health, 26(3), 172-180. PMID: 12875045; PMCID: PMC6683840; LINK.

  5. Dick DM, Nurnberger J, Jr., Edenberg HJ, Goate A, Crowe R, Rice J, Bucholz KK, Kramer J, Schuckit MA, Smith TL, Porjesz B, Begleiter H, Hesselbrock V, Foroud T (2002) Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. Alcoholism: Clinical and Experimental Research, 26(10), 1453-1460. PMID: 12394277; DOI: 10.1097/01.ALC.0000034037.10333.FD.

  6. Edenberg HJ (2002) The collaborative study on the genetics of alcoholism: an update. Alcohol Research and Health, 26(3), 214-218. PMID: 12875050; PMCID: PMC6683843; LINK.

  7. Foroud T, Berrettini WH (2002) Addictive Disorders. In: Rimoin DL, Connor JM, Pyeritz RE, Korf BR (eds.): Principles and Practice of Medical Genetics, Churchill Livingstone, London, pp. 2949-2971.

  8. Hesselbrock V, Mitsuru K (2002) COGA. Bunshi-Seishin Igaku (Journal of Molecular Psychiatry), 2, 1.

  9. Jones K, Begleiter H, Porjesz B, Wang K, Chorlian D (2002) Complexity measures of event related potential surface Laplacian data calculated using the wavelet packet transform. Brain Topography, 14(4), 333-344. PMID: 12137365; DOI: 10.1023/a:1015708928892.

  10. Nurnberger JI, Jr., Foroud T, Flury L, Meyer ET, Wiegand R (2002) Is there a genetic relationship between alcoholism and depression? Alcohol Research and Health, 26(3), 233-240. PMID: 12875052; PMCID: PMC6683839; LINK.

  11. Porjesz B, Almasy L, Edenberg HJ, Wang K, Chorlian DB, Foroud T, Goate A, Rice JP, O’Connor SJ, Rohrbaugh J, Kuperman S, Bauer LO, Crowe RR, Schuckit MA, Hesselbrock V, Conneally PM, Tischfield JA, Li TK, Reich T, Begleiter H (2002) Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proceedings of the National Academy of Sciences of the United States of America, 99(6), 3729-3733. PMID: 11891318; PMCID: PMC122592; DOI: 10.1073/pnas.052716399.

  12. Porjesz B, Begleiter H, Wang K, Almasy L, Chorlian DB, Stimus AT, Kuperman S, O’Connor SJ, Rohrbaugh J, Bauer LO, Edenberg HJ, Goate A, Rice JP, Reich T (2002) Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biological Psychology, 61(1-2), 229-248. PMID: 12385677; DOI: 10.1016/s0301-0511(02)00060-1.

  13. Preuss UW, Schuckit MA, Smith TL, Danko GP, Buckman K, Bierut L, Bucholz KK, Hesselbrock MN, Hesselbrock VM, Reich T (2002) Comparison of 3190 alcohol-dependent individuals with and without suicide attempts. Alcoholism: Clinical and Experimental Research, 26(4), 471-477. PMID: 11981122; DOI: 10.1111/j.1530-0277.2002.tb02563.x.

  14. Preuss UW, Schuckit MA, Smith TL, Danko GR, Dasher AC, Hesselbrock MN, Hesselbrock VM, Nurnberger JI, Jr. (2002) A comparison of alcohol-induced and independent depression in alcoholics with histories of suicide attempts. Journal of Studies on Alcohol, 63(4), 498-502. PMID: 12162295; DOI: 10.15288/jsa.2002.63.498.

  15. Rangaswamy M, Porjesz B, Chorlian DB, Wang K, Jones KA, Bauer LO, Rohrbaugh J, O’Connor SJ, Kuperman S, Reich T, Begleiter H (2002) Beta power in the EEG of alcoholics. Biological Psychiatry, 52(8), 831-842. PMID: 12372655; DOI: 10.1016/s0006-3223(02)01362-8.

  16. Saccone NL, Rice JP, Rochberg N, Williams JT, Goate A, Reich T, Edenberg HJ, Foroud T, Nurnberger JI, Jr., Bierut LJ, Crowe R, Li TK (2002) Linkage for platelet monoamine oxidase (MAO) activity: results from a replication sample. Alcoholism: Clinical and Experimental Research, 26(5), 603-609. PMID: 12045467; DOI: 10.1111/j.1530-0277.2002.tb02581.x.

  17. Schuckit MA, Danko GP, Smith TL, Buckman KR (2002) The five-year predictive validity of each of the seven DSM-IV items for alcohol dependence among alcoholics. Alcoholism: Clinical and Experimental Research, 26(7), 980-987. PMID: 12170107; DOI: 10.1097/01.ALC.0000021333.26894.FD.

  18. Schuckit MA, Smith TL, Danko GP, Reich T, Bucholz KK, Bierut LJ (2002) Similarities in the clinical characteristics related to alcohol dependence in two populations. American Journal on Addictions, 11(1), 1-9. PMID: 11876579; DOI: 10.1080/10550490252801594.

  19. Schuckit MA, Smith TL, Kramer J, Danko G, Volpe FR (2002) The prevalence and clinical course of sedative-hypnotic abuse and dependence in a large cohort. American Journal of Drug and Alcohol Abuse, 28(1), 73-90. PMID: 11853136; DOI: 10.1081/ada-120001282.


2001 [15 Articles]

  1. Almasy L, Porjesz B, Blangero J, Goate A, Edenberg HJ, Chorlian DB, Kuperman S, O’Connor SJ, Rohrbaugh J, Bauer LO, Foroud T, Rice JP, Reich T, Begleiter H (2001) Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. American Journal of Human Genetics, 68(1), 128-135. PMID: 11102287; PMCID: PMC1234905; DOI: 10.1086/316936.

  2. Daw EW, Rice JP, Anthenelli RM, Schuckit MA, Tipp J, Saccone NL, Reich T, Nurnberger JI, Jr., Li TK (2001) A bootstrapped commingling analysis of platelet monoamine oxidase activity levels corrected for cigarette smoking. Psychiatric Genetics, 11(4), 177-185. PMID: 11807407; DOI: 10.1097/00041444-200112000-00001.

  3. Hada M, Porjesz B, Chorlian DB, Begleiter H, Polich J (2001) Auditory P3a deficits in male subjects at high risk for alcoholism. Biological Psychiatry, 49(8), 726-738. PMID: 11313040; DOI: S0006-3223(00)01049-0 [pii].

  4. Hesselbrock V, Begleiter H, Porjesz B, O’Connor S, Bauer L (2001) P300 event-related potential amplitude as an endophenotype of alcoholism–evidence from the collaborative study on the genetics of alcoholism. Journal of Biomedical Science, 8(1), 77-82. PMID: 11173979; DOI: 10.1159/000054016.

  5. Hesselbrock VM, Foroud T, Edenberg H, Nurnberger JI, Reich T, Rice JP (2001) Genetics and alcoholism: the COGA Project. In: Agarwal DP, Seitz HK (eds.): Alcohol in health and disease, Marcel Dekker, New York, pp. 103-124.

  6. Kuperman S, Schlosser SS, Kramer JR, Bucholz K, Hesselbrock V, Reich T, Reich W (2001) Developmental sequence from disruptive behavior diagnosis to adolescent alcohol dependence. American Journal of Psychiatry, 158(12), 2022-2026. PMID: 11729019; DOI: 10.1176/appi.ajp.158.12.2022.

  7. Kuperman S, Schlosser SS, Kramer JR, Bucholz K, Hesselbrock V, Reich T, Reich W (2001) Risk domains associated with an adolescent alcohol dependence diagnosis. Addiction, 96(4), 629-636. PMID: 11300966; DOI: 10.1046/j.1360-0443.2001.96462911.x.

  8. Nurnberger JI, Jr., Foroud T, Flury L, Su J, Meyer ET, Hu K, Crowe R, Edenberg H, Goate A, Bierut L, Reich T, Schuckit M, Reich W (2001) Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder. American Journal of Psychiatry, 158(5), 718-724. PMID: 11329392; DOI: 10.1176/appi.ajp.158.5.718.

  9. Prabhu VR, Porjesz B, Chorlian DB, Wang K, Stimus A, Begleiter H (2001) Visual P3 in female alcoholics. Alcoholism: Clinical and Experimental Research, 25(4), 531-539. PMID: 11329493; DOI: 10.1111/j.1530-0277.2001.tb02247.x.

  10. Schuckit MA, Danko GP, Raimo EB, Smith TL, Eng MY, Carpenter KK, Hesselbrock VM (2001) A preliminary evaluation of the potential usefulness of the diagnoses of polysubstance dependence. Journal of Studies on Alcohol, 62(1), 54-61. PMID: 11271965; DOI: 10.15288/jsa.2001.62.54.

  11. Schuckit MA, Edenberg HJ, Kalmijn J, Flury L, Smith TL, Reich T, Bierut L, Goate A, Foroud T (2001) A genome-wide search for genes that relate to a low level of response to alcohol. Alcoholism: Clinical and Experimental Research, 25(3), 323-329. PMID: 11290841; DOI: 10.1111/j.1530-0277.2001.tb02217.x.

  12. Schuckit MA, Smith TL, Danko GP, Bucholz KK, Reich T, Bierut L (2001) Five-year clinical course associated with DSM-IV alcohol abuse or dependence in a large group of men and women. American Journal of Psychiatry, 158(7), 1084-1090. PMID: 11431230; DOI: 10.1176/appi.ajp.158.7.1084.

  13. Vedeniapin AB, Anokhin AP, Sirevaag E, Rohrbaugh JW, Cloninger CR (2001) Visual P300 and the self-directedness scale of the Temperament and Character Inventory. Psychiatry Research, 101(2), 145-156. PMID: 11286818; DOI: 10.1016/s0165-1781(01)00216-5.

  14. Wang K, Begleiter H, Porjesz B (2001) Warp-averaging event-related potentials. Clinical Neurophysiology, 112(10), 1917-1924. PMID: 11595152; DOI: 10.1016/s1388-2457(01)00640-x.

  15. Zhang XL, Cohen HL, Porjesz B, Begleiter H (2001) Mismatch negativity in subjects at high risk for alcoholism. Alcoholism: Clinical and Experimental Research, 25(3), 330-337. PMID: 11290842; DOI: 10.1097/00000374-200103000-00003.


2000 [13 Articles]

  1. Anokhin AP, Vedeniapin AB, Sirevaag EJ, Bauer LO, O’Connor SJ, Kuperman S, Porjesz B, Reich T, Begleiter H, Polich J, Rohrbaugh JW (2000) The P300 brain potential is reduced in smokers. Psychopharmacology, 149(4), 409-413. PMID: 10867969; DOI: 10.1007/s002130000387.

  2. Bierut LJ, Rice JP, Edenberg HJ, Goate A, Foroud T, Cloninger CR, Begleiter H, Conneally PM, Crowe RR, Hesselbrock V, Li TK, Nurnberger JI, Jr., Porjesz B, Schuckit MA, Reich T (2000) Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking. American Journal of Medical Genetics, 90(4), 299-302. PMID: 10710227; DOI: 10.1002/(sici)1096-8628(20000214)90:4<299::aid-ajmg7>3.0.co;2-y.

  3. Bierut LJ, Schuckit MA, Hesselbrock V, Reich T (2000) Co-occurring risk factors for alcohol dependence and habitual smoking. Alcohol Research and Health, 24(4), 233-241. PMID: 15986718; PMCID: PMC6709743; LINK.

  4. Bucholz KK, Hesselbrock VM, Heath AC, Kramer JR, Schuckit MA (2000) A latent class analysis of antisocial personality disorder symptom data from a multi-centre family study of alcoholism. Addiction, 95(4), 553-567. PMID: 10829331; DOI: 10.1046/j.1360-0443.2000.9545537.x.

  5. Costa L, Bauer L, Kuperman S, Porjesz B, O’Connor S, Hesselbrock V, Rohrbaugh J, Begleiter H (2000) Frontal P300 decrements, alcohol dependence, and antisocial personality disorder. Biological Psychiatry, 47(12), 1064-1071. PMID: 10862806; DOI: 10.1016/s0006-3223(99)00317-0.

  6. Daeppen JB, Smith TL, Danko GP, Gordon L, Landi NA, Nurnberger JI, Jr., Bucholz KK, Raimo E, Schuckit MA (2000) Clinical correlates of cigarette smoking and nicotine dependence in alcohol-dependent men and women. The Collaborative Study Group on the Genetics of Alcoholism. Alcohol and Alcoholism, 35(2), 171-175. PMID: 10787393; DOI: 10.1093/alcalc/35.2.171.

  7. Foroud T, Edenberg HJ, Goate A, Rice J, Flury L, Koller DL, Bierut LJ, Conneally PM, Nurnberger JI, Bucholz KK, Li TK, Hesselbrock V, Crowe R, Schuckit M, Porjesz B, Begleiter H, Reich T (2000) Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. Alcoholism: Clinical and Experimental Research, 24(7), 933-945. PMID: 10923994; DOI: 10.1111/j.1530-0277.2000.tb04634.x.

  8. Hada M, Porjesz B, Begleiter H, Polich J (2000) Auditory P3a assessment of male alcoholics. Biological Psychiatry, 48(4), 276-286. PMID: 10960158; DOI: 10.1016/s0006-3223(00)00236-5.

  9. McClintick J, Edenberg HJ (2000) BlastReport: a perl script to facilitate the use of sequence databases for mapping and clustering. Biotechniques, 29(6), 1272-1276. PMID: 11126131; DOI: 10.2144/00296bc03.

  10. Raimo EB, Smith TL, Danko GP, Bucholz KK, Schuckit MA (2000) Clinical characteristics and family histories of alcoholics with stimulant dependence. Journal of Studies on Alcohol, 61(5), 728-735. PMID: 11022813; DOI: 10.15288/jsa.2000.61.728.

  11. Saccone NL, Kwon JM, Corbett J, Goate A, Rochberg N, Edenberg HJ, Foroud T, Li TK, Begleiter H, Reich T, Rice JP (2000) A genome screen of maximum number of drinks as an alcoholism phenotype. American Journal of Medical Genetics, 96(5), 632-637. PMID: 11054770; DOI: 10.1002/1096-8628(20001009)96:5<632::aid-ajmg8>3.0.co;2-#.

  12. Schuckit MA, Smith TL, Kalmijn J, Tsuang J, Hesselbrock V, Bucholz K (2000) Response to alcohol in daughters of alcoholics: a pilot study and a comparison with sons of alcoholics. Alcohol and Alcoholism, 35(3), 242-248. PMID: 10869242; DOI: 10.1093/alcalc/35.3.242.

  13. Wang K, Begleiter H, Porjesz B (2000) Trilinear modeling of event-related potentials. Brain Topography, 12(4), 263-271. PMID: 10912734; DOI: 10.1023/a:1023455404934.


1999 [18 Articles]

  1. Almasy L, Borecki IB (1999) Exploring genetic analysis of complex traits through the paradigm of alcohol dependence: summary of GAW11 contributions. Genetic Epidemiology, 17 Suppl 1, S1-24. PMID: 10597406; DOI: 10.1002/gepi.1370170704.

  2. Almasy L, Porjesz B, Blangero J, Chorlian DB, O’Connor SJ, Kuperman S, Rohrbaugh J, Bauer LO, Reich T, Polich J, Begleiter H (1999) Heritability of event-related brain potentials in families with a history of alcoholism. American Journal of Medical Genetics, 88(4), 383-390. PMID: 10402506; DOI: 10.1002/(SICI)1096-8628(19990820)88:4<383::AID-AJMG16>3.0.CO;2-J.
  3. Begleiter H, Porjesz B (1999) What is inherited in the predisposition toward alcoholism? A proposed model. Alcoholism: Clinical and Experimental Research, 23(7), 1125-1135. PMID: 10443977; DOI: 10.1111/j.1530-0277.1999.tb04269.x.

  4. Begleiter H, Reich T, Nurnberger J, Jr., Li TK, Conneally PM, Edenberg H, Crowe R, Kuperman S, Schuckit M, Bloom F, Hesselbrock V, Porjesz B, Cloninger CR, Rice J, Goate A (1999) Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genetic Epidemiology, 17 Suppl 1, S25-30. PMID: 10597407; DOI: 10.1002/gepi.1370170705.

  5. Foroud T, Li TK (1999) Genetics of alcoholism: a review of recent studies in human and animal models. American Journal on Addictions, 8(4), 261-278. PMID: 10598210; DOI: 10.1080/105504999305677.

  6. Hesselbrock M, Easton C, Bucholz KK, Schuckit M, Hesselbrock V (1999) A validity study of the SSAGA–a comparison with the SCAN. Addiction, 94(9), 1361-1370. PMID: 10615721; DOI: 10.1046/j.1360-0443.1999.94913618.x.

  7. Kuperman S, Schlosser SS, Lidral J, Reich W (1999) Relationship of child psychopathology to parental alcoholism and antisocial personality disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 38(6), 686-692. PMID: 10361786; DOI: 10.1097/00004583-199906000-00015.

  8. Neuman RJ, Todd RD, Heath AC, Reich W, Hudziak JJ, Bucholz KK, Madden PA, Begleiter H, Porjesz B, Kuperman S, Hesselbrock V, Reich T (1999) Evaluation of ADHD typology in three contrasting samples: a latent class approach. Journal of the American Academy of Child and Adolescent Psychiatry, 38(1), 25-33. PMID: 9893413; DOI: 10.1097/00004583-199901000-00016.

  9. Polich J, Bloom FE (1999) P300, alcoholism heritability, and stimulus modality. Alcohol, 17(2), 149-156. PMID: 10064383; DOI: 10.1016/s0741-8329(98)00047-0.

  10. Raimo EB, Daeppen JB, Smith TL, Danko GP, Schuckit MA (1999) Clinical characteristics of alcoholism in alcohol-dependent subjects with and without a history of alcohol treatment. Alcoholism: Clinical and Experimental Research, 23(10), 1605-1613. PMID: 10549991; DOI: 10.1111/j.1530-0277.1999.tb04050.x.

  11. Reich T, Hinrichs A, Culverhouse R, Bierut L (1999) Genetic studies of alcoholism and substance dependence. American Journal of Human Genetics, 65(3), 599-605. PMID: 10441565; PMCID: PMC1377965; DOI: 10.1086/302561.

  12. Rodriguez Holguin S, Porjesz B, Chorlian DB, Polich J, Begleiter H (1999) Visual P3a in male alcoholics and controls. Alcoholism: Clinical and Experimental Research, 23(4), 582-591. PMID: 10235292; DOI: 10.1111/j.1530-0277.1999.tb04158.x.

  13. Rodriguez Holguin S, Porjesz B, Chorlian DB, Polich J, Begleiter H (1999) Visual P3a in male subjects at high risk for alcoholism. Biological Psychiatry, 46(2), 281-291. PMID: 10418704; DOI: 10.1016/s0006-3223(98)00247-9.

  14. Saccone NL, Rice JP, Rochberg N, Goate A, Reich T, Shears S, Wu W, Nurnberger JI, Jr., Foroud T, Edenberg HJ, Li TK (1999) Genome screen for platelet monoamine oxidase (MAO) activity. American Journal of Medical Genetics, 88(5), 517-521. PMID: 10490709; DOI: 10.1002/(sici)1096-8628(19991015)88:5<517::aid-ajmg15>3.0.co;2-b.

  15. Schuckit MA (1999) New findings in the genetics of alcoholism. JAMA, 281(20), 1875-1876. PMID: 10349877; DOI: 10.1001/jama.281.20.1875.

  16. Schuckit MA, Daeppen JB, Danko GP, Tripp ML, Smith TL, Li TK, Hesselbrock VM, Bucholz KK (1999) Clinical implications for four drugs of the DSM-IV distinction between substance dependence with and without a physiological component. American Journal of Psychiatry, 156(1), 41-49. PMID: 9892296; DOI: 10.1176/ajp.156.1.41.

  17. Stassen HH, Begleiter H, Porjesz B, Rice J, Scharfetter C, Reich T (1999) Structural decomposition of genetic diversity in families with alcoholism. Genetic Epidemiology, 17 Suppl 1, S325-330. PMID: 10597457; DOI: 10.1002/gepi.1370170755.

  18. Williams JT, Begleiter H, Porjesz B, Edenberg HJ, Foroud T, Reich T, Goate A, Van Eerdewegh P, Almasy L, Blangero J (1999) Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. American Journal of Human Genetics, 65(4), 1148-1160. PMID: 10486334; PMCID: PMC1288248; DOI: 10.1086/302571.


1998 [16 Articles]

  1. Anthenelli RM, Tipp J, Li TK, Magnes L, Schuckit MA, Rice J, Daw W, Nurnberger JI, Jr. (1998) Platelet monoamine oxidase activity in subgroups of alcoholics and controls: results from the Collaborative Study on the Genetics of Alcoholism. Alcoholism: Clinical and Experimental Research, 22(3), 598-604. PMID: 9622437; DOI: 10.1111/j.1530-0277.1998.tb04298.x.

  2. Begleiter H, Porjesz B, Reich T, Edenberg HJ, Goate A, Blangero J, Almasy L, Foroud T, Van Eerdewegh P, Polich J, Rohrbaugh J, Kuperman S, Bauer LO, O’Connor SJ, Chorlian DB, Li TK, Conneally PM, Hesselbrock V, Rice JP, Schuckit MA, Cloninger R, Nurnberger J, Jr., Crowe R, Bloom FE (1998) Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalography and Clinical Neurophysiology, 108(3), 244-250. PMID: 9607513; DOI: 10.1016/s0168-5597(98)00002-1.

  3. Bierut LJ, Dinwiddie SH, Begleiter H, Crowe RR, Hesselbrock V, Nurnberger JI, Jr., Porjesz B, Schuckit MA, Reich T (1998) Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. Archives of General Psychiatry, 55(11), 982-988. PMID: 9819066; DOI: 10.1001/archpsyc.55.11.982.

  4. Cloninger CR, Van Eerdewegh P, Goate A, Edenberg HJ, Blangero J, Hesselbrock V, Reich T, Nurnberger J, Jr., Schuckit M, Porjesz B, Crowe R, Rice JP, Foroud T, Przybeck TR, Almasy L, Bucholz K, Wu W, Shears S, Carr K, Crose C, Willig C, Zhao J, Tischfield JA, Li TK, Conneally PM, et al. (1998) Anxiety proneness linked to epistatic loci in genome scan of human personality traits. American Journal of Medical Genetics, 81(4), 313-317. PMID: 9674977; DOI: 10.1002/(sici)1096-8628(19980710)81:4<313::aid-ajmg7>3.0.co;2-u.

  5. Edenberg HJ, Foroud T, Goate A, Rice J, Reich T, Cloninger RC, Nurnberger JI, Li T-K, Conneally PM, Tischfield JA, Crowe R, Hesselbrock V, Schuckit M, Porjesz B, Begleiter H (1998) Genetics of Alcoholism (Letter to the Editor). Science, 282, 1265. DOI: 10.1126/science.282.5392.1265i.

  6. Edenberg HJ, Foroud T, Koller DL, Goate A, Rice J, Van Eerdewegh P, Reich T, Cloninger CR, Nurnberger JI, Jr., Kowalczuk M, Wu B, Li TK, Conneally PM, Tischfield JA, Wu W, Shears S, Crowe R, Hesselbrock V, Schuckit M, Porjesz B, Begleiter H (1998) A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism. Alcoholism: Clinical and Experimental Research, 22(2), 505-512. PMID: 9581660; DOI: 10.15288/jsad.2007.68.362.

  7. Edenberg HJ, Reich T, Foroud T, Goate A, Rice J, Begleiter H (1998) Genes Affecting Alcohol Dependence and Related Phenotypes: A Genomic Survey by the Collaborative Study on the Genetics of Alcoholism (COGA). Miami Nature Biology Short Reports, 9, 71-72.

  8. Edenberg HJ, Reynolds J (1998) Improved method for detecting the long and short promoter alleles of the serotonin transporter gene HTT (SLC6A4). Psychiatric Genetics, 8(3), 193-195. PMID: 9800223; DOI: 10.1097/00041444-199800830-00011.

  9. Edenberg HJ, Reynolds J, Koller DL, Begleiter H, Bucholz KK, Conneally PM, Crowe R, Goate A, Hesselbrock V, Li TK, Nurnberger JI, Jr., Porjesz B, Reich T, Rice JP, Schuckit M, Tischfield JA, Foroud T (1998) A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence. Alcoholism: Clinical and Experimental Research, 22(5), 1080-1085. PMID: 9726278; DOI: 10.1111/j.1530-0277.1998.tb03704.x.

  10. Foroud T, Bucholz KK, Edenberg HJ, Goate A, Neuman RJ, Porjesz B, Koller DL, Rice J, Reich T, Bierut LJ, Cloninger CR, Nurnberger JI, Jr., Li TK, Conneally PM, Tischfield JA, Crowe R, Hesselbrock V, Schuckit M, Begleiter H (1998) Linkage of an alcoholism-related severity phenotype to chromosome 16. Alcoholism: Clinical and Experimental Research, 22(9), 2035-2042. PMID: 9884148; DOI: 10.1111/j.1530-0277.1998.tb05913.x.

  11. Goate AM, Edenberg HJ (1998) The genetics of alcoholism. Curr Opin Genet Dev, 8(3), 282-286. ? ? ? 9691005; DOI: 10.1016/s0959-437x(98)80082-8.

  12. Porjesz B, Begleiter H (1998) Genetic basis of event-related potentials and their relationship to alcoholism and alcohol use. Journal of Clinical Neurophysiology, 15(1), 44-57. PMID: 9502512; DOI: 10.1097/00004691-199801000-00006.

  13. Porjesz B, Begleiter H, Reich T, Van Eerdewegh P, Edenberg HJ, Foroud T, Goate A, Litke A, Chorlian DB, Stimus A, Rice J, Blangero J, Almasy L, Sorbell J, Bauer LO, Kuperman S, O’Connor SJ, Rohrbaugh J (1998) Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism. Alcoholism: Clinical and Experimental Research, 22(6), 1317-1323. PMID: 9756048; DOI: 10.1111/j.1530-0277.1998.tb03914.x.

  14. Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li TK, Conneally PM, Nurnberger JI, Jr., Tischfield JA, Crowe RR, Cloninger CR, Wu W, Shears S, Carr K, Crose C, Willig C, Begleiter H (1998) Genome-wide search for genes affecting the risk for alcohol dependence. American Journal of Medical Genetics, 81(3), 207-215. PMID: 9603606; DOI: 10.1002/(SICI)1096-8628(19980508)81:3<207::AID-AJMG1>3.0.CO;2-T.

  15. Schuckit MA, Daeppen JB, Tipp JE, Hesselbrock M, Bucholz KK (1998) The clinical course of alcohol-related problems in alcohol dependent and nonalcohol dependent drinking women and men. Journal of Studies on Alcohol, 59(5), 581-590. PMID: 9718111; DOI: 10.15288/jsa.1998.59.581.

  16. Schuckit MA, Smith TL, Daeppen JB, Eng M, Li TK, Hesselbrock VM, Nurnberger JI, Jr., Bucholz KK (1998) Clinical relevance of the distinction between alcohol dependence with and without a physiological component. American Journal of Psychiatry, 155(6), 733-740. PMID: 9619144; DOI: 10.1176/ajp.155.6.733.


1997 [14 Articles]

  1. Alexander JE, Polich J (1997) Handedness and P300 from auditory stimuli. Brain and Cognition, 35(2), 259-270. PMID: 9356165; DOI: 10.1006/brcg.1997.0941.

  2. Blangero J, Almasy L (1997) Multipoint oligogenic linkage analysis of quantitative traits. Genetic Epidemiology, 14(6), 959-964. PMID: 9433607; DOI: 10.1002/(SICI)1098-2272(1997)14:6<959::AID-GEPI66>3.0.CO;2-K.

  3. Crowe RR, Kramer JR, Hesselbrock V, Manos G, Bucholz KK (1997) The utility of the Brief MAST’ and the CAGE’ in identifying alcohol problems: results from national high-risk and community samples. Archives of Family Medicine, 6(5), 477-483. PMID: 9305692; DOI: 10.1001/archfami.6.5.477.

  4. Dinwiddie SH (1997) Characteristics of injection drug users derived from a large family study of alcoholism. Comprehensive Psychiatry, 38(4), 218-229. PMID: 9202879; DOI: 10.1016/s0010-440x(97)90030-4.

  5. Easton C, Bauer LO (1997) Neuropsychological differences between alcohol-dependent and cocaine-dependent patients with or without problematic drinking. Psychiatry Research, 71(2), 97-103. PMID: 9255854; DOI: 10.1016/s0165-1781(97)00052-8.

  6. Koziol JA, Alexander JE, Bauer LO, Kuperman S, Morzorati S, OConnor SJ, Rohrbaugh J, Porjesz B, Begleiter H, Polich J (1997) A graphical technique for displaying correlation matrices. American Statistician, 51(4), 301-304. DOI: Doi 10.2307/2685895.

  7. Polich J, Alexander JE, Bauer LO, Kuperman S, Morzorati S, O’Connor SJ, Porjesz B, Rohrbaugh J, Begleiter H (1997) P300 topography of amplitude/latency correlations. Brain Topography, 9(4), 275-282. PMID: 9217986; DOI: 10.1007/BF01464482.

  8. Porjesz B, Begleiter H (1997) Event-related potentials in COA’s. Alcohol Health and Research World, 21(3), 236-240. PMID: 15706775; PMCID: PMC6826815; LINK.

  9. Rohrbaugh JW, Dunham DN, Stewart PA, Bauer LO, Kuperman S, O’Connor SJ, Porjesz B, Begleiter H (1997) Slow brain potentials in a visual-spatial memory task: topographic distribution and inter-laboratory consistency. International Journal of Psychophysiology, 25(2), 111-122. PMID: 9101336; DOI: 10.1016/s0167-8760(96)00714-3.

  10. Schuckit MA, Smith TL, Tipp JE (1997) The Self-Rating of the Effects of alcohol (SRE) form as a retrospective measure of the risk for alcoholism. Addiction, 92(8), 979-988. PMID: 9376780; DOI: 10.1111/j.1360-0443.1997.tb02977.x.

  11. Schuckit MA, Tipp JE, Bergman M, Reich W, Hesselbrock VM, Smith TL (1997) Comparison of induced and independent major depressive disorders in 2,945 alcoholics. American Journal of Psychiatry, 154(7), 948-957. PMID: 9210745; DOI: 10.1176/ajp.154.7.948.

  12. Schuckit MA, Tipp JE, Bucholz KK, Nurnberger JI, Jr., Hesselbrock VM, Crowe RR, Kramer J (1997) The life-time rates of three major mood disorders and four major anxiety disorders in alcoholics and controls. Addiction, 92(10), 1289-1304. PMID: 9489046; DOI: 10.1111/j.1360-0443.1997.tb02848.x.

  13. Schuckit MA, Tipp JE, Smith TL, Bucholz KK (1997) Periods of abstinence following the onset of alcohol dependence in 1,853 men and women. Journal of Studies on Alcohol, 58(6), 581-589. PMID: 9391917; DOI: 10.15288/jsa.1997.58.581.

  14. Schuckit MA, Tipp JE, Smith TL, Wiesbeck GA, Kalmijn J (1997) The relationship between Self-Rating of the Effects of alcohol and alcohol challenge results in ninety-eight young men. Journal of Studies on Alcohol, 58(4), 397-404. PMID: 9203121; DOI: 10.15288/jsa.1997.58.397.


1996 [12 Articles]

  1. Alexander JE, Bauer LO, Kuperman S, Morzorati S, O’Connor SJ, Rohrbaugh J, Porjesz B, Begleiter H, Polich J (1996) Hemispheric differences for P300 amplitude from an auditory oddball task. International Journal of Psychophysiology, 21(2-3), 189-196. PMID: 8792206; DOI: 10.1016/0167-8760(95)00047-x.

  2. Bucholz KK, Heath AC, Reich T, Hesselbrock VM, Kramer JR, Nurnberger JI, Jr., Schuckit MA (1996) Can we subtype alcoholism? A latent class analysis of data from relatives of alcoholics in a multicenter family study of alcoholism. Alcoholism: Clinical and Experimental Research, 20(8), 1462-1471. PMID: 8947326; DOI: 10.1111/j.1530-0277.1996.tb01150.x.

  3. Easton C, Bauer LO (1996) Neuropsychological correlates of urine toxicology results. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 20(6), 969-982. PMID: 8888104; DOI: 10.1016/0278-5846(96)00077-2.

  4. Grau C, Begleiter H (1996) Genetics of alcoholism: an international perspective. Alcoholism: Clinical and Experimental Research, 20(8 Suppl), 78A-81A. PMID: 8947240; DOI: 10.1111/j.1530-0277.1996.tb01751.x.

  5. Hesselbrock V (1996) Female alcoholism: new perspectives-findings from the COGA Study. Collaborative Study on the Genetics of Alcoholism. Alcoholism: Clinical and Experimental Research, 20(8 Suppl), 168A-171A. PMID: 8947258; DOI: 10.1111/j.1530-0277.1996.tb01769.x.

  6. Porjesz B, Begleiter H, Litke A, Bauer LO, Kuperman S, O�Connor SJ, Rohrbaugh J (1996) Visual P3 as a potential phenotypic marker for alcoholism: Evidence from the COGA national project. In: Ogura C, Koga Y, Shimokochi M (eds.): Recent Advances in Event-Related Brain Potential Research, Elsevier Science, Holland, pp. 539-549.

  7. Quaid KA, Dinwiddie H, Conneally PM, Nurnberger JI, Jr. (1996) Issues in genetic testing for susceptibility to alcoholism: lessons from Alzheimer’s disease and Huntington’s disease. Alcoholism: Clinical and Experimental Research, 20(8), 1430-1437. PMID: 8947321; DOI: 10.1111/j.1530-0277.1996.tb01145.x.

  8. Reich T, Begleiter H, Edenberg H, Cloninger R (1996) A genomic survey of alcohol dependence and related phenotypes: results from the Collaborative Study on the Genetics of Alcoholism (COGA). Alcoholism: Clinical and Experimental Research, 20(8 Suppl), 133A-137A. PMID: 8947252; DOI: 10.1111/j.1530-0277.1996.tb01763.x.

  9. Samar VJ, Begleiter H, Chapa JO, Raghuveer M, Orlando M, Chorlian D (1996) Matched Meyer neural wavelets for clinical and experimental analysis of auditory and visual evoked potentials. In: 8th European Signal Processing Conference (EUSIPCO 1996), IEEE, pp. 387-390; LINK.

  10. Schuckit MA, Tipp JE, Anthenelli RM, Bucholz KK, Hesselbrock VM, Nurnberger JI, Jr. (1996) Anorexia nervosa and bulimia nervosa in alcohol-dependent men and women and their relatives. American Journal of Psychiatry, 153(1), 74-82. PMID: 8540597; DOI: 10.1176/ajp.153.1.74.

  11. Schuckit MA, Tsuang JW, Anthenelli RM, Tipp JE, Nurnberger JI, Jr. (1996) Alcohol challenges in young men from alcoholic pedigrees and control families: a report from the COGA project. Journal of Studies on Alcohol, 57(4), 368-377. PMID: 8776678; DOI: 10.15288/jsa.1996.57.368.

  12. Wiesbeck GA, Schuckit MA, Kalmijn JA, Tipp JE, Bucholz KK, Smith TL (1996) An evaluation of the history of a marijuana withdrawal syndrome in a large population. Addiction, 91(10), 1469-1478. PMID: 8917915; DOI: 10.1046/j.1360-0443.1996.911014696.x.


1995 [19 Articles]

  1. Alexander JE, Polich J (1995) P300 differences between sinistrals and dextrals. Brain Research: Cognitive Brain Research, 2(4), 277-282. PMID: 8580741; DOI: 10.1016/0926-6410(95)90019-5.

  2. Alexander JE, Porjesz B, Bauer LO, Kuperman S, Morzorati S, O’Connor SJ, Rohrbaugh J, Begleiter H, Polich J (1995) P300 hemispheric amplitude asymmetries from a visual oddball task. Psychophysiology, 32(5), 467-475. PMID: 7568641; DOI: 10.1111/j.1469-8986.1995.tb02098.x.

  3. Begleiter H (1995) The Collaborative Study on the Genetics of Alcoholism: Overview. Alcohol Health and Research World, 19(2), 228-229. PMID: 31798102; PMCID: PMC6875768; LINK.

  4. Begleiter H, Reich T, Hesselbrock V, Porjesz B, Li T-K, Schuckit MA, Edenberg HJ, Rice JP (1995) The Collaborative Study on the Genetics of Alcoholism. Alcohol Health and Research World, 19(2), 228-236. PMID: 31798102; PMCID: PMC6875768; LINK.

  5. Bucholz KK, Hesselbrock VM, Shayka JJ, Nurnberger JI, Jr., Schuckit MA, Schmidt I, Reich T (1995) Reliability of individual diagnostic criterion items for psychoactive substance dependence and the impact on diagnosis. Journal of Studies on Alcohol, 56(5), 500-505. PMID: 7475029; DOI: 10.15288/jsa.1995.56.500.

  6. Edenberg HJ (1995) The Collaborative Study on the Genetics of Alcoholism: Molecular Genetics. Alcohol Health and Research World, 19(3), 228-236. PMID: 31798102; PMCID: PMC6875768; LINK.

  7. Hesselbrock V (1995) The Collaborative Study on the Genetics of Alcoholism: Clinical Assessment. Alcohol Health and Research World, 19(2), 230-233. PMID: 31798102; PMCID: PMC6875768; LINK.

  8. Kuperman S, Porjesz B, Arndt S, Bauer L, Begleiter H, Cizadlo T, O’Connor S, Rohrbaugh J (1995) Multi-center N400 ERP consistency using a primed and unprimed word paradigm. Electroencephalography and Clinical Neurophysiology, 94(6), 462-470. PMID: 7607100; DOI: 10.1016/0013-4694(94)00312-9.

  9. Li T-K (1995) The Collaborative Study on the Genetics of Alcoholism: Biochemical Markers. Alcohol Health and Research World, 19(2), 234-235. PMID: 31798102; PMCID: PMC6875768; LINK.

  10. Porjesz B, Begleiter H (1995) The Collaborative Study on the Genetics of Alcoholism: Neurophysiological Component. Alcohol Health and Research World, 19(2), 233-234. PMID: 31798102; PMCID: PMC6875768; LINK.

  11. Reich T (1995) The Collaborative Study on the Genetics of Alcoholism: Data Collection. Alcohol Health and Research World, 19(2), 229-230. PMID: 31798102; PMCID: PMC6875768; LINK.

  12. Rice JP (1995) The Collaborative Study on the Genetics of Alcoholism: Data Analysis. Alcohol Health and Research World, 19(2), 236. PMID: 31798102; PMCID: PMC6875768; LINK.

  13. Rice JP, Neuman RJ, Hoshaw SL, Daw EW, Gu C (1995) TDT with covariates and genomic screens with mod scores: their behavior on simulated data. Genetic Epidemiology, 12(6), 659-664. PMID: 8787990; DOI: 10.1002/gepi.1370120623.

  14. Rice JP, Reich T, Bucholz KK, Neuman RJ, Fishman R, Rochberg N, Hesselbrock VM, Nurnberger JI, Jr., Schuckit MA, Begleiter H (1995) Comparison of direct interview and family history diagnoses of alcohol dependence. Alcoholism: Clinical and Experimental Research, 19(4), 1018-1023. PMID: 7485811; DOI: 10.1111/j.1530-0277.1995.tb00983.x.

  15. Schuckit MA (1995) The Collaborative Study on the Genetics of Alcoholism: Alcohol Challenge Component. Alcohol Health and Research World, 19(2), 235. PMID: 31798102; PMCID: PMC6875768; LINK.

  16. Schuckit MA, Anthenelli RM, Bucholz KK, Hesselbrock VM, Tipp J (1995) The time course of development of alcohol-related problems in men and women. Journal of Studies on Alcohol, 56(2), 218-225. PMID: 7760569; DOI: 10.15288/jsa.1995.56.218.

  17. Schuckit MA, Hesselbrock VM, Tipp J, Nurnberger JI, Jr., Anthenelli RM, Crowe RR (1995) The prevalence of major anxiety disorders in relatives of alcohol dependent men and women. Journal of Studies on Alcohol, 56(3), 309-317. PMID: 7623470; DOI: 10.15288/jsa.1995.56.309.

  18. Schuckit MA, Tipp JE, Reich T, Hesselbrock VM, Bucholz KK (1995) The histories of withdrawal convulsions and delirium tremens in 1648 alcohol dependent subjects. Addiction, 90(10), 1335-1347. PMID: 8616462; DOI: 10.1046/j.1360-0443.1995.901013355.x.

  19. Schuckit MA, Tipp JE, Smith TL, Shapiro E, Hesselbrock VM, Bucholz KK, Reich T, Nurnberger JI, Jr. (1995) An evaluation of type A and B alcoholics. Addiction, 90(9), 1189-1203. PMID: 7580817; DOI: 10.1046/j.1360-0443.1995.90911894.x.


1994 [6 Articles]

  1. Alexander JE, Polich J, Bloom FE, Bauer LO, Kuperman S, Rohrbaugh J, Morzorati S, O’Connor SJ, Porjesz B, Begleiter H (1994) P300 from an auditory oddball task: inter-laboratory consistency. International Journal of Psychophysiology, 17(1), 35-46. PMID: 7961052; DOI: 10.1016/0167-8760(94)90053-1.

  2. Bucholz KK, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock VM, Nurnberger JI, Jr., Reich T, Schmidt I, Schuckit MA (1994) A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. Journal of Studies on Alcohol, 55(2), 149-158. PMID: 8189735; DOI: 10.15288/jsa.1994.55.149.

  3. Cohen HL, Wang W, Porjesz B, Bauer L, Kuperman S, O’Connor SJ, Rohrbaugh J, Begleiter H (1994) Visual P300: an interlaboratory consistency study. Alcohol, 11(6), 583-587. PMID: 7865162; DOI: 10.1016/0741-8329(94)90087-6.

  4. Schuckit MA, Hesselbrock V (1994) Alcohol dependence and anxiety disorders: what is the relationship? American Journal of Psychiatry, 151(12), 1723-1734. PMID: 7977877; DOI: 10.1176/ajp.151.12.1723.

  5. Schuckit MA, Hesselbrock V, Tipp J, Anthenelli R, Bucholz K, Radziminski S (1994) A comparison of DSM-III-R, DSM-IV and ICD-10 substance use disorders diagnoses in 1922 men and women subjects in the COGA study. Collaborative Study on the Genetics of Alcoholism. Addiction, 89(12), 1629-1638. PMID: 7866247; DOI: 10.1111/j.1360-0443.1994.tb03764.x.

  6. Schuckit MA, Tipp JE, Kelner E (1994) Are daughters of alcoholics more likely to marry alcoholics? American Journal of Drug and Alcohol Abuse, 20(2), 237-245. PMID: 8042605; DOI: 10.3109/00952999409106784.


1992 [1 Article]

  1. Twitchell GR, Hertzog CA, Klein JL, Schuckit MA (1992) The anatomy of a follow-up. British Journal of Addiction, 87(9), 1327-1333. PMID: 1392554; DOI: 10.1111/j.1360-0443.1992.tb02741.x.


1990 [1 Article]

  1. Rice J (1990) The use of computer simulation in genetic linkage studies. Alcohol Research and Health, 14(3), 253. LINK.